Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT07820254Recruiting
How well people with pulmonary fibrosis can breathe in
This study looks at how well people with pulmonary fibrosis can breathe in and aims to see if their breathing flow rate is linked to their condition. It may help doctors understand more about the disease and plan better care.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06443658RecruitingPhase 3
The ELTGOL breathing technique: Clearing phlegm faster
This study tests whether inhaling a saltwater spray before a special breathing exercise (ELTGOL) helps people with bronchiectasis cough up phlegm more easily. It's for adults who have daily phlegm, recent flare-ups, and have not smoked much.
GironaAges 18 years+ - NCT03621566Recruiting
Sleep apnea registry for adults with non-obstructive events
This study builds a registry to learn more about sleep apnea patterns, especially cases where most breathing events are not caused by blocked airway tissue. You may be able to join if you’re an adult with a specific sleep test result.
AalstAges 18 years+ - NCT06485544RecruitingPhase 2
Immunotherapy before surgery for small cell lung cancer
This trial tests adding a drug called adebrelimab (a type of immunotherapy) before surgery for people with early-stage small cell lung cancer that can be removed. The goal is to see if it helps shrink the tumor and improve outcomes.
Xi'an, ShannxiAges 18–75 - NCT06483347RecruitingPhase 2
Immunotherapy combo for inoperable lung cancer
This trial tests a combination of immunotherapy drugs (checkpoint inhibitors) delivered directly into the liver along with standard treatment, as a first option for people with inoperable lung cancer. It aims to see if this approach can help shrink tumors and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06487052Recruiting
Catheter-based clot-dissolving drug for intermediate-high risk pulmonary embolism
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
Saint PetersburgAges 18 years+ - NCT06306456RecruitingPhase 1/Phase 2
GH21 combined with osimertinib for advanced lung cancer
This trial tests a new drug (GH21) combined with the targeted therapy osimertinib (Tagrisso) for people with advanced non-small cell lung cancer that has an EGFR mutation and has stopped responding to a similar treatment. The goal is to see if the combination can help when the cancer has progressed.
Hefei, AnhuiAges 18 years+ - NCT07813299Recruiting
Antibiotic rinse in the lungs for bronchiectasis flare-ups
This study tests whether placing a common antibiotic (amikacin) directly into the lungs during a bronchoscopy helps people with bronchiectasis recover faster from sudden flare-ups. Participation involves a bronchoscopy and a lung rinse, which may reduce infection and improve breathing.
Ningbo, ZhejiangAges 18–80 - NCT07809256RecruitingPhase 3
Combination treatment for advanced lung cancer with a RET gene change
This trial tests a combination of two medicines (pembrolizumab and lenvatinib) for people with advanced non-small cell lung cancer that has a specific RET gene change. The treatment may help slow down or shrink the cancer, and the study checks how well people tolerate it.
Saint PetersburgAges 18 years+ - NCT07814248RecruitingPhase 1
TS-104 for advanced solid tumors
This trial tests a new drug called TS-104 for people with certain advanced solid tumors that have stopped responding to standard treatments. The drug is given alone (not with other cancer treatments) to see if it can shrink tumors or slow their growth.
Maumee, OhioAges 18 years+ - NCT07816185RecruitingPhase 3
Inhaled study drug for pulmonary hypertension with lung scarring
This study tests an inhaled medication called mosliciguat for people with pulmonary hypertension (high blood pressure in the lungs) caused by certain types of lung scarring. It may help improve your ability to exercise and manage symptoms.
Kissimmee, FloridaAges 18–85 - NCT07810010RecruitingPhase 2
Vaccine for RSV and HMPV in adults 60 and older
This study tests a new vaccine that protects against two common respiratory viruses: RSV and HMPV. It aims to see if the vaccine is safe and works well in older adults, who are at higher risk for serious illness from these viruses.
Bruse, Australian Capital TerritoryAges 60 years+ - NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+ - NCT06491043RecruitingPhase 2
Stem cells for COPD: safety and early effectiveness study
This trial tests whether an infusion of donor stem cells can help people with moderate to severe COPD breathe easier. If you are a current or former smoker aged 40 to 80, your symptoms are stable, and your lung function meets specific targets, you may be able to join.
New Taipei CityAges 40–80 - NCT03562052Recruiting
Lung cancer screening for high-risk workers and smokers
This study offers lung cancer screening (using scans) for people at high risk due to smoking history and workplace exposure to cancer-causing substances. It aims to find lung cancers earlier and understand who benefits most from regular screening.
BordeauxAges 55–74 - NCT06492421RecruitingPhase 2
Immunotherapy before surgery for lung cancer
This trial tests whether giving two immunotherapy drugs directly into the tumor before surgery can shrink non-small cell lung cancer and improve outcomes. It is for people with early-stage (IIIA) lung cancer who are candidates for surgery.
Guanzhou, GuangdongAges 18–75 - NCT06491290Recruiting
Florence ER visits and local air quality study
This study looks at how air quality and weather in Florence affect how many people come to the emergency room. By joining, you help researchers understand if outdoor conditions like pollution or temperature might be linked to health problems.
FlorenceAges 14 years+ - NCT07810283Enrolling by invitation
Using a new imaging belt to guide breathing support
This study tests a new belt that takes pictures of your lungs to help doctors adjust your breathing support. It may help make non-invasive ventilation (a mask that helps you breathe) more comfortable and effective for people with chronic breathing problems.
LondonAges 18 years+ - NCT07814690Recruiting
Choking rescue methods study for adults and children
This study looks at how well different first-aid methods work when someone is choking. If you or your child choked and received help from a bystander or a healthcare provider, this study might help improve future rescue advice.
Calgary, AlbertaAges 3 years+ - NCT07815223RecruitingPhase 2
Immunotherapy and targeted drug after chemoradiation for limited-stage small cell lung cancer
This trial tests whether adding two medications—tislelizumab (an immunotherapy that helps your immune system fight cancer) and anlotinib (a targeted drug that blocks blood supply to tumors)—after standard chemoradiation can help keep limited-stage small cell lung cancer from coming back. It may offer a new option to improve outcomes for patients who have already responded to initial treatment.
Yantai, ShandongAges 18–75 - NCT07816263Recruiting
Guaraná supplement for cancer-related fatigue
This trial tests whether a natural supplement called guaraná can help reduce fatigue in people undergoing cancer treatment. Guaraná contains caffeine and other compounds that may boost energy and improve well-being.
Bogotá, Bogota D.C.Ages 18 years+ - NCT07815366Enrolling by invitation
Eccentric cycling exercise for healthy adults
This study tests a special kind of exercise bike that works your muscles in a different way (called eccentric cycling) to see if it helps healthy people improve their fitness. You would ride this bike for 3 months, and the study team will check your progress.
Zurich, Canton of ZurichAges Any age - NCT07816835RecruitingPhase 4
Comparing nebulizer vs inhaler for COPD treatment
This study compares two ways of taking COPD maintenance medicines: using a nebulizer vs. using a handheld inhaler. The goal is to see which method works better for people with severe COPD, so researchers can help guide treatment choices.
Saint Charles, MissouriAges 60 years+ - NCT07813377Recruiting
Blood clotting test to predict outcomes after brain tumor surgery
This study looks at a special blood test (called thromboelastography) that checks how well your blood clots. The goal is to see if this test can predict how the surgery goes and whether you might get a blood clot after surgery. If you join, the test will be done before and after your brain surgery, and you will be monitored for any blood clot complications.
BarcelonaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.