Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT06161285Recruiting
Gut germs and immune response in infant bronchiolitis
This study looks at how the germs in a baby's gut and their immune system respond to bronchiolitis (a common lung infection). If your baby is under 12 months and gets bronchiolitis during the RSV season, their participation could help us understand why some babies get very sick and others don't.
ClamartAges 1 day–1 year - NCT06795971Recruiting
Comparing oxygen methods for hypoxemic respiratory failure
This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.
Nanjing, JiangsuAges 18 years+ - NCT06846762Recruiting
DNA/RNA co-testing for advanced lung cancer that has stopped responding to first treatment
This study is for people with advanced non-small cell lung cancer whose tumors do not have certain genetic changes (called driver mutations) and whose first treatment did not work well or caused bad side effects within 6 months. The researchers want to use a special test (DNA/RNA-NGS) to look for hidden genetic alterations that might explain why the cancer didn't respond.
Shanghai, Shanghai MunicipalityAges Any age - NCT06534385Recruiting
Clean Air Study: HEPA Purifiers for Health
This study tests whether HEPA air purifiers can improve indoor air quality and health in rural Alaska homes that use woodstoves or have a smoker. If you join, you'll receive a purifier and help researchers see if cleaner air makes a difference.
Bethel, AlaskaAges Up to 5 years - NCT06692972Recruiting
How lung cancer tumors change after high-dose radiation
This study looks at how the main lung tumor shrinks or changes after a complete course of high-dose radiation in people with stage II or III lung cancer. It uses scans taken before and after treatment to track the results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07361510RecruitingPhase 3
Pumitamig vs Keytruda for advanced lung cancer with high PD-L1
This trial compares an experimental drug called Pumitamig with the approved immunotherapy drug Pembrolizumab (Keytruda) as the first treatment for advanced lung cancer that has high PD-L1 levels. The goal is to see which drug works better and has fewer side effects.
Daphne, AlabamaAges 18 years+ - NCT07357051RecruitingPhase 3
Flu treatment study for children ages 2 to 12
This trial tests a new oral medicine (JKN2301) for children with the flu. It aims to see if the medicine is safe and works well to treat flu symptoms like fever and cough.
Guangzhou, GuangdongAges 2–11 - NCT07355868RecruitingEarly Phase 1
Cell therapy for COPD
This trial is testing a new type of cell therapy called REGEND007 for people with COPD. It looks at whether the treatment can help improve how far you can walk and your overall breathing.
Yiwu, ZhejiangAges 40–80 - NCT07361497RecruitingPhase 3
New Drug vs Standard Drug After Chemoradiation for Stage 3 Lung Cancer
This study tests a new drug, pumitamig, against an older drug, durvalumab, for people with stage 3 non-small cell lung cancer that cannot be removed by surgery and has not progressed after chemotherapy and radiation. The goal is to see which drug works better to keep the cancer from growing.
Daphne, AlabamaAges 18 years+ - NCT07361562RecruitingPhase 1
Study of CGT4255 for advanced solid tumors with HER2 changes
This trial tests an oral drug called CGT4255 for people with advanced solid tumors that have certain changes in the HER2 gene or related proteins. It aims to see if the drug is safe and effective.
Scottsdale, ArizonaAges 18 years+ - NCT07358806RecruitingPhase 1
Study of OCT-598 for advanced solid tumors
This trial tests a new drug called OCT-598, alone or with chemotherapy, for people with advanced solid tumors that have not responded to other treatments. It aims to see if the combination is safe and effective.
Goyang-siAges 18 years+ - NCT07354711RecruitingPhase 1/Phase 2
Study of 3H-10000 for advanced solid tumors
This trial tests a new drug called 3H-10000 for people with solid tumors that cannot be removed by surgery or have spread. The goal is to see if it is safe and works against cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06848647Recruiting
Treating sleep apnea to improve metabolism
This study tests whether treating sleep apnea with CPAP improves your body's metabolism (how your body uses energy). It's for people who have sleep apnea and are about to start CPAP therapy.
Uppsala, Uppsala CountyAges 18 years+ - NCT06849167RecruitingPhase 2
Immunotherapy with low-dose chemoradiation for advanced lung cancer
This trial tests combining immunotherapy with a shorter course of chemoradiation for locally advanced non-small cell lung cancer that hasn't spread. It aims to see if this approach is more effective and tolerable than standard treatment.
BeijingAges 18–70 - NCT07357558Recruiting
Reproductive health experiences in adults with PCD
This study is a conversation-based research project to understand how reproductive issues affect adults with Primary Ciliary Dyskinesia (PCD), a rare lung condition. By sharing your experiences, you can help doctors and researchers better support patients like you.
SouthamptonAges 18 years+ - NCT07358910Recruiting
Tracking infectious diseases in communities
This study looks at how infections spread in villages in Cambodia. If you live in a participating village, you might help us understand and prevent disease outbreaks.
Phnom Penh, Phnom PenhAges 2–75 - NCT07359040Recruiting
Testing a new drug before surgery for lung cancer
This trial studies whether a new drug called Ivonescimab can improve outcomes when given before surgery for non-small cell lung cancer. It may help shrink tumors and make them easier to remove.
Beijing, Beijing MunicipalityAges Any age - NCT07359482RecruitingPhase 3
Fluvoxamine for fatigue after covid-19
This study tests the antidepressant fluvoxamine to see if it can reduce long-term fatigue in adults who developed severe tiredness after a covid-19 infection. You may join if your fatigue started or got worse after covid and has lasted at least 3 months.
Amsterdam-ZuidoostAges 18–70 - NCT07358676RecruitingPhase 2
Study of bemotuzumab plus chemo and anlotinib for advanced small cell lung cancer
This trial tests a combination of the targeted drug bemotuzumab, chemotherapy, and anlotinib (which blocks blood vessel growth) followed by radiation therapy for people with extensive-stage small cell lung cancer who haven't had treatment yet. The goal is to see if this approach helps control the cancer.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07359261RecruitingPhase 2
Personalized breathing support for obese patients on a ventilator
This study tests a new way to adjust breathing machine settings to match each person's lungs, aiming to improve breathing for patients with obesity. It involves placing a small balloon in the esophagus to measure lung pressure and guide ventilator settings.
Edmonton, AlbertaAges 18 years+ - NCT07359599RecruitingPhase 4
IV iron for exercise and quality of life in pulmonary hypertension
This study tests whether intravenous (IV) iron can help people with pulmonary hypertension feel better, have more energy, and enjoy a better quality of life. You may qualify if you have a type of pulmonary hypertension and low iron levels.
AalstAges 18 years+ - NCT07356310Recruiting
Body scan and breathing test for airway health
This trial uses a special breathing test to measure how your airways react. It helps doctors understand airway tone and reactivity, which may relate to conditions like asthma.
Rochester, New YorkAges 18 years+ - NCT07356076Recruiting
Using electrical impedance tomography to look at lung disease
This study uses a special imaging test called electrical impedance tomography (EIT) to look at how well the lungs work in people with lung diseases like COPD, asthma, pneumonia, or long-term effects from COVID-19. It also includes healthy volunteers to compare results.
OlomoucAges 18 years+ - NCT07359287Recruiting
Study on antibiotic use for respiratory infections
This study tests a program to help doctors prescribe antibiotics more carefully for common respiratory infections like colds, flu, bronchitis, and sinusitis. It may lead to better treatment for you.
CaenAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.