Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT04525716Recruiting
Study of how COVID-19 affected surgery patients
This study looks at how the COVID-19 pandemic changed outcomes and experiences for people who had surgery in Stockholm during the study period. It may help hospitals prepare better plans for patients during future outbreaks.
StockholmAges Any age - NCT04524585Recruiting
Tested a muscle-relaxing treatment for severe low-oxygen breathing
This study tests whether partially relaxing the breathing-related muscles can help people with severe low oxygen while they are on a breathing machine. It may improve how well the lungs work by changing the way the muscles affect breathing.
Toronto, OntarioAges 18 years+ - NCT04524091Recruiting
Predict breathing effort response to higher ventilator pressure
This trial looks at how much breathing effort changes when the ventilator uses a higher pressure in people who are recovering from ARDS. The goal is to predict who will respond better so care can be adjusted more safely and effectively.
San Martín, Buenos AiresAges 18 years+ - NCT04527419Recruiting
Surgery for early lung adenocarcinoma with specific CT findings
This study looks at whether people with a very early type of lung cancer can safely have curative surgery when their CT scan shows a ground-glass type spot with certain size and shape measurements. It aims to help doctors choose the right surgery approach based on the scan features and final pathology.
ShanghaiAges 18–75 - NCT04527315Recruiting
COVID-19 survivors health registry and follow-up scans
This study enrolls adults who had COVID-19 to track longer-term health effects and match them with people who did not have COVID-19. Depending on eligibility, you may be asked to complete questionnaires and possibly have MRI or X-ray scans.
New York, New YorkAges 18 years+ - NCT04530383RecruitingPhase 2
Metformin add-on for adult cystic-fibrosis related diabetes on CF meds
This trial tests whether adding metformin can improve blood-sugar control and related lung cell function in adults who have cystic-fibrosis–related diabetes (CFRD) and are already taking CFTR modulator therapy. It may help if your diabetes is still not well controlled despite those CF medicines.
Kansas City, KansasAges 18 years+ - NCT04532346RecruitingEarly Phase 1
Hydroxychloroquine for genetic lung disease in children
This early-phase trial studies whether hydroxychloroquine can help children with certain genetic causes of interstitial lung disease (lung scarring/inflammation). It is designed for kids who are currently stable and have not recently taken hydroxychloroquine.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT04538937Recruiting
Study of high eosinophils causing lung/airway damage
This registry study looks at adults with high eosinophils (a type of immune cell) that are believed to be causing damage in the airways or lungs. It aims to better identify these eosinophils and understand what is going on so future treatments can improve.
InnsbruckAges 18 years+ - NCT04539977RecruitingPhase 2
PD-L1 antibody plus chemotherapy for limited-stage small-cell lung cancer
This Phase 2 study tests whether adding a PD-L1 antibody to chemotherapy helps people with newly diagnosed limited-stage small-cell lung cancer live longer and control the cancer better. It may benefit patients who have not had any prior cancer treatment for SCLC and can meet health and lab requirements.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04543461Recruiting
Lung health study for young adults in the U.S.
This study follows young adults to learn about lung health and risk factors. It may help researchers better understand how breathing symptoms and exposures affect future lung outcomes.
Birmingham, AlabamaAges 25–35 - NCT04544774Recruiting
Nasal allergen test to start and track allergy shots
This study uses a nasal allergen “provocation” test to help decide how to start and monitor allergy immunotherapy (allergy shots or drops). It may help doctors better track whether the treatment is working for people with allergic rhinitis.
Leuven, Vlaam BrabantAges 18–60 - NCT04545424RecruitingPhase 2
Testing cooling treatment for severe lung failure in ICU patients
This trial tests whether therapeutic cooling (hypothermia) can improve outcomes in people with ARDS, a serious lung condition causing breathing failure. It may help by reducing harmful inflammation and lung injury, but eligibility is time-sensitive and requires ICU monitoring.
Los Angeles, CaliforniaAges 18–85 - NCT04545242RecruitingPhase 4
Dexamethasone for severe lung failure from infections on ventilators
This trial studies whether dexamethasone (a steroid medicine) improves outcomes in adults who have sudden, severe breathing failure caused by an infection while they are on a breathing machine. It may help reduce inflammation in the lungs during critical illness.
Terrassa, BarcelonaAges 18 years+ - NCT04551378Recruiting
Study of how COVID affected young people with cancer
This study looks at how the COVID-19 pandemic affected the experiences of teenagers and young adults with cancer, including people who finished treatment. It may help improve support for cancer patients and survivors during public health crises.
Houston, TexasAges 18–39 - NCT04550104RecruitingPhase 1
Durvalumab with radiation for lung cancer patients
This trial tests adding durvalumab (an immune therapy) to a radiation treatment plan for people with non-small cell lung cancer (NSCLC) who can’t safely have chemotherapy at the same time or surgery first. It aims to improve cancer control after radiation by helping the immune system recognize and fight the tumor.
BelfastAges 18 years+ - NCT04555161Recruiting
Test of an implanted device for pulmonary arterial hypertension
This trial studies an implanted system (the Aria CV Pulmonary Hypertension System) to treat pulmonary arterial hypertension, a serious lung-blood vessel and heart condition. It aims to see whether the device can improve outcomes for people who are still sick despite existing PH medicines.
La Jolla, CaliforniaAges 18 years+ - NCT04558450Recruiting
Study how COVID-19 affects blood vessel stiffness and aging
This study looks at how having COVID-19 may affect your blood vessels over the following months. It may help doctors understand long-term “vascular aging” and who is most at risk, based on how sick you were during your COVID illness.
NancyAges 18 years+ - NCT04557293Recruiting
Testing how thinking decisions affect CPAP use
This trial studies whether a person’s decision-making skills affect how well they use CPAP, a common treatment for sleep apnea. It may help you and your care team improve CPAP adherence so therapy is more effective.
PaviaAges 18–80 - NCT04557995Recruiting
Blood-filter treatment for chronic high-altitude sickness
This trial studies “erythrocytapheresis,” a procedure that filters part of the blood, to improve symptoms of chronic mountain sickness caused by long-term living at high altitude. It may help people with high-altitude–related headaches, dizziness, shortness of breath, poor sleep, fatigue, and related signs.
Xigazê, TibetAges 18 years+ - NCT04565483RecruitingPhase 4
Test a blood-test signature to predict benralizumab benefit
This trial studies whether a specific “signature” from asthma tests can predict who will respond to benralizumab (a severe asthma biologic). If you qualify, the researchers will compare your test results to how well benralizumab controls your asthma and prevents flare-ups.
Aix-en-ProvenceAges 18–75 - NCT04573062Recruiting
Study how people recover from COVID over time
This study follows adults who recently recovered from COVID-19 to better understand what happens during recovery and afterward. It may help researchers identify who is at risk for longer-lasting symptoms (often called “PASC”) and what changes over time.
Bethesda, MarylandAges 18–100 - NCT04572503Recruiting
Surgery for mild to moderate sleep apnea not helped by CPAP
This trial looks at a modified palate surgery to treat mild to moderate obstructive sleep apnea in people whose CPAP machine isn’t working for them. It may help if your sleep apnea is caused by the tissue behind the soft palate collapsing rather than other airway areas.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT04577599Recruiting
Mobile low-dose lung CT screening for ages 40–54
This study offers mobile low-dose CT scans to help find lung problems early in people at higher risk from smoking. You may be invited because of your age and smoking history, and the results may guide next steps with your care team.
Charlotte, North CarolinaAges 40–54 - NCT04578171Recruiting
Mepolizumab for severe asthma flare-ups after treatment
This trial studies whether mepolizumab can reduce ongoing or returning asthma flare-ups in people with severe asthma. If you have severe asthma that still keeps flaring, this may help by targeting a specific inflammation pathway involved in some asthma cases.
Québec, QuebecAges 18–90
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.