Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,770 recruiting studies in this area right now.
By phase
- Not applicable6,416
- Phase 2492
- Phase 1248
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder144
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York256
- Texas209
- Maryland175
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,770 total
- NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+ - NCT07223905Recruiting
Cognitive and walking training for memory and mobility risk
This study tests a combined brain and walking exercise program for older adults who have normal thinking but show early signs of thinking or memory problems and slower walking. The goal is to see if this training can improve memory and movement, and potentially prevent further decline.
Kansas City, KansasAges 65 years+ - NCT07222930Enrolling by invitation
Learning about amyloid and tau test results
This study helps people understand their results from brain scans that measure amyloid and tau proteins, which are linked to Alzheimer's disease. It is for adults 45 and older who are part of specific Alzheimer's research programs and have no dementia diagnosis.
Madison, WisconsinAges 45–89 - NCT07221383Enrolling by invitation
A smartphone app to help reduce heavy drinking
This study tests a smartphone program to help people who want to cut back on heavy drinking. It focuses on delivering support via text messages over the course of a month.
New Haven, ConnecticutAges 18 years+ - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT07226570Recruiting
Ibogaine brain mapping study for opioid use disorder
This study uses MRI and EEG scans to map how ibogaine affects the brain in people with opioid use disorder. You must already be scheduled to receive ibogaine treatment in Tijuana, Mexico, on your own, as the study does not cover treatment costs.
Irvine, CaliforniaAges 21–70 - NCT07226219RecruitingPhase 1
Medication to help attention in children with sickle cell disease
This study tests whether a common medication called methylphenidate (often used for ADHD) can help children with sickle cell disease who have attention or memory problems. If the child qualifies, the study may offer a new way to improve focus and daily functioning.
Memphis, TennesseeAges 8–17 - NCT07226674Recruiting
Study of gut health and plant nutrients for brain health
This trial tests whether a natural plant compound can help support memory and thinking in people at higher risk for Alzheimer's disease. You may qualify if you are over 50, overweight, eat a typical Western diet, and have a family history of Alzheimer's.
ColeraineAges 50 years+ - NCT07228182Recruiting
Brain stimulation study for gambling disorder
This trial tests a non-invasive brain stimulation method called high-intensity transcranial alternating current stimulation to see if it can reduce gambling urges and behavior in people with gambling disorder.
ShanghaiAges 18–60 - NCT07221409Recruiting
Virtual reality to help cancer patients feel better during treatment
This trial tests whether using virtual reality can help reduce stress, anxiety, and other emotional symptoms in people being treated for cancer. Patients undergoing chemotherapy, bone marrow transplant, or CAR-T therapy may be eligible.
Jacksonville, FloridaAges 18–90 - NCT07228468Recruiting
Home brain stimulation for depression
This trial tests if a gentle electrical current applied to the head at home can help reduce symptoms of major depression. You would use a device for short sessions over several weeks, while continuing your usual care.
CardiffAges 18 years+ - NCT07223398Recruiting
Making HIV care decisions with people who've been in the justice system
This trial helps people recently involved with the justice system and who use stimulants or opioids decide on HIV prevention or treatment. It tests a shared decision-making approach for taking HIV medication (ART) or PrEP.
New Haven, ConnecticutAges 18 years+ - NCT07227324Recruiting
Cannabis use registry for cancer patients
This study is a registry that collects information from people with cancer who use cannabis. It aims to better understand how cannabis affects cancer symptoms and improve care.
Saint Louis Park, MinnesotaAges 18 years+ - NCT07225010Recruiting
Video Parenting Program for Young Children with Behavior Problems
This study tests a special parenting program (Parent-Child Interaction Therapy) done through video calls. It aims to help children aged 2–6 with behavior problems and to strengthen family relationships.
Charleston, South CarolinaAges 2–7 - NCT07224607Recruiting
Light therapy for early Alzheimer's disease
This study tests a type of light therapy (called transcranial photobiomodulation) to see if it can help people with early-stage Alzheimer's. It involves coming to Cedars-Sinai for weekly sessions over a period of time.
Los Angeles, CaliforniaAges 55–89 - NCT07223346Recruiting
Fitness and therapy for Latina cancer survivors
This trial offers a program combining exercise and mental health support for Latina women in Colorado who have recently finished cancer treatment or are still undergoing it. It aims to improve well-being through group sessions focused on physical activity and coping skills.
Fort Collins, ColoradoAges 18 years+ - NCT07224165Recruiting
Digital support for teens who self-injure
This study tests a digital program (like a smartphone app) to help teens who have been hurting themselves on purpose. The goal is to see if using the app can reduce self-injury and help you feel better.
Chicago, IllinoisAges 14–18 - NCT07222982Recruiting
Social groups for autistic young adults
This study tests whether a social group program helps autistic young adults make friends and feel more connected. If you are 18–30, have a high school diploma, and can travel to Philadelphia each week, you may be able to join.
Philadelphia, PennsylvaniaAges 18–30 - NCT07225400Recruiting
Brain training for navigation in mild memory loss
This trial tests a new way to help people with mild memory problems improve their sense of direction and navigation. You will be asked to do tasks while wearing a special cap that records brain activity, to see how your brain responds to spatial challenges.
Manhattan, New YorkAges 65 years+ - NCT07222280Recruiting
Alzheimer's dementia and brain inflammation trial
This trial tests if treating brain inflammation can help older adults hospitalized with sudden confusion or cognitive issues. It may help those without a prior dementia diagnosis but who have toxic or metabolic causes for their symptoms.
Crossville, TennesseeAges 60–90 - NCT07227948RecruitingPhase 2
Testing semaglutide for cocaine use disorder
This study tests whether semaglutide, a medication used for weight management, can help reduce cocaine use in people with cocaine use disorder. You may qualify if you have a body mass index (BMI) of 25 or higher and recently used cocaine.
Houston, TexasAges 18 years+ - NCT07227337Recruiting
Being safe, healthy, and empowered for immigrant women
This study tests a program to help immigrant women who have faced violence and feel symptoms of PTSD or depression. It aims to improve your safety, health, and wellbeing.
Baltimore, MarylandAges 18 years+ - NCT07226739RecruitingPhase 4
Toilet training program for children with delays
This study tests a program to help children with developmental delays overcome bowel and bladder accidents. It involves a structured toileting schedule and support for caregivers.
Atlanta, GeorgiaAges 5–12
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,770 recruiting psychiatry studies from the U.S. registry right now, out of 12,391 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.