Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,199 recruiting studies in this area right now.
By phase
- Not applicable6,804
- Phase 2511
- Phase 1256
- Phase 3244
- Phase 4214
- Phase 1/Phase 298
- Phase 2/Phase 372
Top conditions
- Depression419
- Anxiety411
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia227
- Mild Cognitive Impairment201
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia154
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders83
Leading sponsors
- VA Office of Research and Development104
- Yale University96
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California528
- New York267
- Massachusetts261
- Texas224
- Maryland176
- Pennsylvania174
- Florida154
- Alabama118
- Arizona117
- Connecticut114
Recruiting studies8,198 total
- NCT06572683Enrolling by invitation
Novel TMS for hard-to-treat depression
This trial tests a new type of transcranial magnetic stimulation (TMS) for people with severe depression that hasn't improved with multiple medications or therapy. It uses a different frequency pattern to target brain circuits.
Los Angeles, CaliforniaAges 21–75 - NCT06596044Recruiting
Suicide prevention after leaving community care
This study tests a program to support veterans after emergency mental health care at a non-VA hospital in Northern New England. If you've recently had suicidal thoughts, the program may help keep you safe after discharge.
White River Junction, VermontAges 18 years+ - NCT07387107Recruiting
Reducing stress with virtual reality and special sounds
This study tests if a short session of virtual reality and specially designed sounds (binaural beats) can help healthy adults feel less stressed. Volunteers attend a single 60-minute session.
Bad NauheimAges 18 years+ - NCT07655986Recruiting
Suicide prevention program for at-risk adults
This study tests a special program from a university designed to prevent suicidal behavior in adults who have been seen in the emergency room. The program provides close follow-up and support to help keep you safe.
Salamanca, SalamancaAges 18 years+ - NCT06591091RecruitingPhase 2
Clemastine for Depression in Older Adults
This study tests if adding clemastine (an allergy medication) to standard antidepressants can improve brain health and boost treatment response in adults over 60 with depression.
Chicago, IllinoisAges 60 years+ - NCT06589973Recruiting
Alcohol Withdrawal: Predicting Complications with Lab Tests
This trial looks at how certain lab results and health factors affect outcomes in people going through alcohol withdrawal. It aims to find better ways to predict and manage complications.
Mexico CityAges 18–80 - NCT05976867Recruiting
Parent program to prevent child sexual abuse
This study tests whether a parent-focused program can prevent child sexual abuse by teaching parents skills to support their children. You may be able to help both the program work better and learn how well it can be used in real life.
New York, New YorkAges 15 years+ - NCT07735078Recruiting
Smart balance and thinking exercise for older adults
This study tests a smart digital tool that combines balance and thinking exercises to help older adults stay steady and prevent falls. If you are 55+ and can walk a short distance, you may be able to join.
Taipei, TaipeiAges 55 years+ - NCT06584422Recruiting
Online program for depression in older adults
This study tests an online program called Empower@Home that helps older adults with symptoms of depression. It compares the program to usual care to see if it improves mood and well-being.
Ann Arbor, MichiganAges 50 years+ - NCT07734545RecruitingEarly Phase 1
Parenting young children check-up study
This trial tests a check-up program for parents of young children. It aims to help parents who are concerned about their child's behavior or emotions.
Detroit, MichiganAges 18 years+ - NCT06566235Recruiting
Testing DBT therapy for teens with emotional issues in Taiwan
This trial is testing a type of talk therapy called Dialectical Behavior Therapy (DBT), adapted for teenagers in Taiwan who struggle with strong emotions like sadness, worry, or hyperactivity. The study will see if this culturally-adjusted therapy helps teens feel better and manage their emotions.
TaipeiAges 12–18 - NCT05825040Recruiting
Testing an online mental health program for anxiety and depression
This trial tests an “online” mental health approach to help people with moderate to severe anxiety and/or depression. If you qualify, you may be invited to use the program and share feedback as part of a study.
Shatin, N.T.Ages 17 years+ - NCT06555094Recruiting
Adding a mobile app to brief therapy for suicide risk
This trial studies whether adding a mobile app to brief counseling sessions can help people who are having thoughts of suicide or have recently attempted suicide. It aims to find a more effective way to support your mental health using technology you already have.
Piscataway, New JerseyAges 18 years+ - NCT05991739Recruiting
Study on racism and support for Latina immigrant families
This study tests a group program that helps Latina immigrant mothers and their teenage children talk about and cope with the effects of racism. It aims to improve family well-being and communication.
Chicago, IllinoisAges 14–17 - NCT06541002Recruiting
SHIFT app for stem cell transplant survivors' sexual health
This trial tests a mobile app (SHIFT) designed to help people who have had a stem cell transplant and are experiencing sexual health concerns. It aims to see if the app can improve your well-being.
Coral Gables, FloridaAges 18 years+ - NCT06540300Enrolling by invitation
Brain stimulation for non-suicidal self-injury
This study tests whether a gentle brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce self-harm urges and behaviors. It is for people who have non-suicidal self-injury (when you hurt yourself on purpose without wanting to die).
Nanjing, JiangsuAges 10–55 - NCT05994612Recruiting
Suicide prevention for homeless youth using substances
This trial tests a program to help reduce suicide risk in young people who are homeless and use alcohol or drugs. It may provide support and strategies to keep them safe.
Columbus, OhioAges 15–24 - NCT05996172Recruiting
Outpatient program for recent suicidal thoughts or attempt
This study tests a new outpatient program for people who recently had suicidal thoughts or made an attempt. The program includes therapy and support from a family member or friend, helping you recover safely outside the hospital.
Seattle, WashingtonAges 13–21 - NCT06002763Recruiting
Patient-reported health survey for new mothers
This trial tests whether a simple questionnaire (PROMIS-29) can help measure physical and mental health in women who have recently given birth. It aims to improve follow-up care for all mothers, including those with healthy babies admitted to the NICU.
Toronto, OntarioAges 18–55 - NCT06529055Enrolling by invitation
Caffeine and nicotine pouch effects on exercise and brain function
This trial tests how caffeine and nicotine pouches affect your body during exercise, including heart function, thinking, and behavior. It looks at short bursts of high-intensity activity in healthy men who already exercise regularly.
Hattiesburg, MississippiAges 21–40 - NCT06002477RecruitingEarly Phase 1
Attention study in sickle cell disease
This trial tests a medication to see if it can improve attention in people with sickle cell disease. It may help with thinking and focus.
Nashville, TennesseeAges 55 years+ - NCT06622889Enrolling by invitation
Can changing how you see aging help memory?
This study tests whether changing how older adults think about aging can help with memory concerns. If you are 60+ and feel your memory or thinking is declining (but tests are normal), you may be able to join.
Beijing, Beijing MunicipalityAges 60 years+ - NCT06588582Recruiting
How cannabis influences perception and feelings
This study looks at how smoking cannabis affects your perception and emotions. It aims to understand why some people use cannabis to cope with stress or negative feelings.
Boulder, ColoradoAges 21–65 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,199 recruiting psychiatry studies from the U.S. registry right now, out of 13,332 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.