Dermatology
Skin clinical trials
Psoriasis, eczema, skin cancers, and other conditions of the skin and connective tissue. We’re tracking 5,021 recruiting studies in this area right now.
By phase
- Not applicable2,807
- Phase 2752
- Phase 1522
- Phase 3382
- Phase 1/Phase 2294
- Phase 4205
- Phase 2/Phase 359
Top conditions
- Breast Cancer1,192
- Melanoma175
- Metastatic Breast Cancer138
- Rheumatoid Arthritis132
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Breast Neoplasms111
- Triple Negative Breast Cancer111
- Colorectal Cancer94
- Ovarian Cancer92
- Psoriasis85
- Breast Carcinoma79
- Lung Cancer77
- Prostate Cancer70
- Rheumatoid Arthritis (RA)68
- Diabetic Foot Ulcer59
- Cancer58
- Systemic Lupus Erythematosus (SLE)52
Leading sponsors
- Fudan University64
- M.D. Anderson Cancer Center51
- Novartis Pharmaceuticals49
- Memorial Sloan Kettering Cancer Center48
- Mayo Clinic40
- AstraZeneca38
- Assistance Publique - Hôpitaux de Paris37
- National Cancer Institute (NCI)37
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University35
- Second Affiliated Hospital, Zhejiang University, School of Medicine30
Where studies are running
- California406
- Arizona152
- Alabama129
- Florida126
- New York111
- Texas106
- Maryland95
- Massachusetts88
- Pennsylvania72
- North Carolina67
Recruiting studies5,021 total
- NCT04349527Recruiting
Comparing breast-conserving surgeries and how you feel after
This trial compares two breast-conserving surgery techniques to see how they affect cosmetic results (how the breast looks), quality of life, and patient satisfaction. It may help guide the best surgical approach for people eligible for breast conservation.
BudapestAges 18–65 - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT04158843Recruiting
Local surgery vs comfort treatment for limited breast cancer spread
This trial compares a more direct local treatment (targeting a small, limited spot) versus a comfort-focused palliative approach for breast cancer that has spread only to one side of the upper arm bone or breastbone area. It aims to see which approach works better while keeping side effects manageable.
Hangzhou, ZhejiangAges 18–75 - NCT04372277RecruitingPhase 4
Adding Enstilar to Taltz for plaque psoriasis
This trial studies whether using Enstilar (a medicated skin spray/foam) together with Taltz works better than staying on Taltz alone for chronic plaque psoriasis. It focuses on adults with a specific amount of body skin affected by psoriasis who have already been on Taltz for at least 24 weeks.
East Windsor, New JerseyAges 18 years+ - NCT04389164Recruiting
Tissue-made skin graft for thick, raised scars
This trial studies a lab-made (tissue-engineered) skin scaffold that is used to repair hypertrophic (thick, raised) scars using your own tissue. It aims to improve scar healing after surgical repair, and you would have follow-up visits to check results and side effects.
Guangzhou, GuangdongAges Up to 80 years - NCT04095351Recruiting
Study of connective tissue disease affecting the lungs
This study looks at people aged 18 and older who have a connective tissue disease and lung involvement. It aims to better understand how these lung problems progress and may help doctors choose better care.
InnsbruckAges 18–80 - NCT04437160RecruitingPhase 2
Chemo after surgery for triple-negative breast cancer with leftover tumor
This Phase 2 study tests chemotherapy given after surgery for people with triple-negative breast cancer who still have cancer left after initial (neoadjuvant) chemo. It may help lower the chance the cancer comes back in people at higher risk based on leftover tumor and lymph node findings.
Beijing, Beijing MunicipalityAges 18–75 - NCT04072653Recruiting
Sentinel node biopsy versus watchful waiting after PET
This trial studies whether taking a sample from the sentinel lymph node (a first lymph node that can be involved) improves care compared with observation, after a breast cancer PET scan of the armpit area. It may help people with certain early breast cancers avoid unnecessary procedures if the lymph nodes look negative on scans.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04481763RecruitingPhase 1/Phase 2
Camrelizumab plus radiation for early triple-negative breast cancer
This trial studies whether adding camrelizumab (an immunotherapy drug) to radiation can improve outcomes and be safe for people with early triple-negative breast cancer. It is designed for specific early-stage cases after breast surgery, using tumor and blood tests to match the cancer’s features.
Nanchang, JiangxiAges 18–75 - NCT04493723Recruiting
Biopsies and blood tests for advanced melanoma
This study looks at serial (repeated) tumour biopsies and blood samples in people with advanced melanoma. The goal is to understand biomarkers and disease changes over time, which may help improve future treatment decisions.
ManchesterAges 16 years+ - NCT03646955Recruiting
Partial breast radiation versus no radiation after lumpectomy
This trial compares giving radiation only to part of the breast versus not giving radiation at all after breast-conserving surgery. It’s meant for women with early, hormone-driven breast cancer to see if skipping radiation can be safe and reduce treatment burden.
SantiagoAges 60 years+ - NCT04538937Recruiting
Study of high eosinophils causing lung/airway damage
This registry study looks at adults with high eosinophils (a type of immune cell) that are believed to be causing damage in the airways or lungs. It aims to better identify these eosinophils and understand what is going on so future treatments can improve.
InnsbruckAges 18 years+ - NCT04291378Recruiting
Proton versus standard radiation for early breast cancer
This trial compares two types of radiation—proton therapy and standard photon therapy—for early breast cancer after surgery. It’s mainly for people whose usual radiation plan would put a higher dose to the heart and/or lungs, aiming to reduce that exposure.
AalborgAges 18 years+ - NCT03591276RecruitingPhase 1/Phase 2
Doxorubicin plus pembrolizumab for hormone-resistant breast cancer
This Phase 1b/2 trial tests a combination of pegylated liposomal doxorubicin and pembrolizumab for breast cancer that no longer responds to hormone treatment. It aims to see how well the combination works and how safely it can be given to patients with advanced disease.
JerusalemAges 18 years+ - NCT04646759RecruitingPhase 3
Fulvestrant or capecitabine plus pyrotinib for metastatic breast cancer
This Phase 3 trial tests adding pyrotinib to standard hormone-based treatments (fulvestrant or capecitabine) to slow or control metastatic breast cancer. It’s for tumors that are hormone-receptor positive and HER2 positive, where standard options have been used before.
Guangzhou, GuangdongAges 18–80 - NCT04665882Recruiting
Prediction tool for arm swelling after breast cancer surgery
This trial tests a prediction tool (a “nomogram”) to estimate who is at risk of developing breast cancer–related lymphedema, or long-term arm swelling, after surgery. If you fit the surgery and lymph node criteria, your information may help personalize follow-up and prevention.
Wuhan, HubeiAges 18–80 - NCT04045691Recruiting
Real-world targeted treatment for BRAF-mutant melanoma
This trial studies how doctors use encorafenib plus binimetinib for real-world care in people with BRAF V600–mutated melanoma that can’t be removed by surgery or has spread. It may help improve understanding of which patients benefit and what happens in everyday clinical practice.
GrazAges 18 years+ - NCT04601116RecruitingPhase 3
Atorvastatin for hormone-positive breast cancer to prevent recurrence
This Phase 3 study tests whether taking atorvastatin (a cholesterol-lowering medicine) can improve outcomes for women with estrogen-receptor–positive breast cancer. It may help by affecting cancer-related pathways and reducing risk of recurrence or progression.
AarhusAges 18 years+ - NCT04669873Recruiting
Partial breast radiation vs whole breast radiation after lumpectomy
This trial studies whether treating only part of the breast with radiation works as well as treating the whole breast in people with early breast cancer after lumpectomy. It may help reduce radiation exposure to healthy tissue, while still controlling the cancer.
São Paulo, São PauloAges 50–90 - NCT04800289Recruiting
Joint skin and joint clinic satisfaction and impact study
This study looks at how patients feel about a combined skin-and-joint doctor visit and whether that visit helps. It mainly involves people who attend the hospital’s joint rheumatologist/dermatologist consultation.
Le MansAges 18 years+ - NCT04126876RecruitingPhase 2
IMO-2125 skin injection for thick, early-stage melanoma
This trial tests whether an injection given into the skin (IMO-2125) can improve outcomes for people with thicker primary melanoma that has not spread to lymph nodes or other organs. Participants also have planned surgery to remove the tumor and check a sentinel lymph node.
AmsterdamAges 18 years+ - NCT04019678Recruiting
Breast cancer study after chemotherapy with small underarm node spread
This study looks at whether it’s safe and effective to avoid removing many underarm lymph nodes in some people who, after chemotherapy, still seem to have only tiny (“micro”) cancer deposits in the sentinel lymph node. It may help reduce treatment side effects while keeping cancer control.
Rozzano, MIAges 18–75 - NCT04878666Recruiting
Breast cancer chest-wall recurrence quality of life with heat treatment
This trial studies how a special heating radiation treatment (“hyperthermia radiotherapy”) affects quality of life in people whose breast cancer has come back in the chest area. It may help show whether this treatment approach is tolerable and beneficial for everyday well-being.
Tübingen, Baden-WurttembergAges 18 years+ - NCT04331093RecruitingPhase 2
Pre-surgery treatment for stage III–IV melanoma with two medicines
This trial tests two medicines given before surgery to shrink stage III–IV acral melanoma (a melanoma type on the hands/feet) and improve outcomes. If the tumors respond, surgery can happen afterward as planned.
Changchun, JilinAges 18–75
Common questions
- How many skin clinical trials are recruiting?
- Clin2 is tracking 5,021 recruiting dermatology studies from the U.S. registry right now, out of 7,720 we cover in this area in total.
- What does “Skin” cover here?
- Psoriasis, eczema, skin cancers, and other conditions of the skin and connective tissue. We group each study into skin based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a skin trial near me?
- Use the search to filter skin studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.