Clinical trials
Acute Heart Failure clinical trials
Below are recruiting acute heart failure clinical trials, each written for real people, not researchers. We’re tracking 413 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04419480Recruiting
Monitoring to help prevent complications after cardiogenic shock
This study tests a special monitoring approach (likely using an implanted device) to help prevent serious complications after you survive cardiogenic shock in the hospital. It may help the care team detect problems earlier so treatments can start sooner.
Falls Church, VirginiaAges 18 years+ - NCT04323371Recruiting
Study testing for heart-shock to reduce future events
This trial studies how to identify different types of “cardiogenic shock,” a serious drop in heart blood flow. It aims to use detailed patient information to guide care and possibly lower the chance of dangerous outcomes.
MilanAges 18–74 - NCT00733590Recruiting
Study after ICD generator replacement for heart attack patients
This study follows people who had a prior heart attack and later received a replacement ICD (a device that helps prevent sudden dangerous heart rhythms). It is observational, meaning it mainly looks at outcomes and device-related information rather than testing a new drug.
Washington D.C., District of ColumbiaAges 18–85 - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Los Angeles, CaliforniaAges 18 years+ - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT07422688Enrolling by invitation
Using light scans to find heart artery blockages
This trial uses a special light-based scan (optical coherence tomography, or OCT) to help doctors see inside your heart arteries and find the exact blockage causing your heart attack. It may help guide treatment more precisely.
GenkAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07532811Recruiting
How Lungs Distribute Air and Blood in Critically Ill Children
This pilot study uses a special belt around the chest to measure how air and blood are distributed in the lungs of children on breathing machines in the intensive care unit. The goal is to better understand lung function in critically ill children.
Bron, FranceAges Up to 12 years - NCT07329036Recruiting
Liver support therapy for acute liver failure
This trial tests two different blood-filtering treatments for people with severe liver failure who are waiting for or unable to receive a liver transplant. It aims to see how these treatments affect blood clotting, inflammation, and organ function.
PragueAges 18–75 - NCT07188038Recruiting
Comparing low vs high breathing tube pressure on diaphragm health
This trial compares two levels of positive end-expiratory pressure (PEEP) in patients on a breathing machine. It looks at how these pressures affect diaphragm function, how well the lungs work, and how efficiently you breathe.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT05442710RecruitingPhase 2
Immune cell treatment for recovery from severe septic shock
This trial tests an immune-cell treatment given outside the body to help people recover from septic shock, a life-threatening reaction to infection. It aims to improve survival and organ recovery in patients who are still very ill despite standard care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06955260RecruitingPhase 3
Empagliflozin for Fontan circulatory failure
This trial tests if a diabetes medicine called empagliflozin can help people with Fontan circulatory failure feel better and do more of their daily activities.
Vancouver, British ColumbiaAges 18 years+ - NCT06066502RecruitingPhase 3
Precision ventilation for ARDS
This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.
Tucson, ArizonaAges 18 years+ - NCT07661940RecruitingPhase 2
SP16 for kidney protection during heart surgery
This trial tests a drug called SP16 to see if it can prevent acute kidney injury in people with chronic kidney disease who are having elective heart surgery with a heart-lung machine. It aims to help preserve kidney function after surgery.
Erlangen, BavariaAges 18 years+ - NCT05895136RecruitingPhase 2
Albumin plus blood thinner for severe cirrhosis after hospital recovery
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
ClichyAges 18–80 - NCT03547232RecruitingPhase 4
Indomethacin given early to treat acute pancreatitis
This trial tests whether taking indomethacin (an anti-inflammatory medicine) early can improve outcomes in people with acute pancreatitis. You might be eligible if your pancreatitis is diagnosed soon and you meet specific lab, imaging, and safety requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT06788275Recruiting
Can exercise improve blood vessel health after a heart attack?
This study looks at whether aerobic exercise can improve blood vessel health in people who have had a heart attack or chest pain (angina). If you qualify, you'll join a monitored exercise program.
Alicante, AlicanteAges 45–75 - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT07616921Recruiting
Home Exercise Program for Heart Health During Leukemia Transplant
This study tests whether doing gentle exercise at home can help protect your heart during stem cell transplant treatment for acute myeloid leukemia (a type of blood cancer). You'll use a smartphone app to guide daily workouts designed to be safe and manageable during your treatment.
Seattle, WashingtonAges 18 years+ - NCT07283809Recruiting
Heart care study for patients with common heart problems
This study is collecting information about people with common heart conditions to help doctors learn how to offer better care. If you have had a heart attack, heart failure, or atrial fibrillation, your experience can help improve treatment for others.
Montevarchi, AREZZOAges 18 years+ - NCT07300384Recruiting
Blood flow restriction training for knee pain relief before surgery
This study tests whether a special type of strength training (called blood flow restriction training) can reduce pain in people with severe knee arthritis who are waiting for knee replacement surgery. The training uses a cuff on the thigh to lightly restrict blood flow while doing exercises until failure.
Valencia, ValenciaAges 50–85 - NCT03589729RecruitingPhase 2
Dexrazoxane to help protect the heart during blood-cancer chemo
This Phase 2 study tests dexrazoxane, a heart-protecting medicine, to reduce heart side effects from chemotherapy in people with certain blood cancers. If you qualify, you would receive dexrazoxane along with chemotherapy, and the team will monitor your heart function closely.
Houston, TexasAges 12 years+ - NCT06398457RecruitingEarly Phase 1
Darzalex Before Stem Cell Transplant for High-Risk Graft Failure
This trial tests giving a drug called Darzalex Faspro before the usual desensitization and a stem cell transplant for people at high risk of graft failure due to donor-specific antibodies. The goal is to prevent the transplant from failing.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for acute heart failure?
- Yes. Clin2 currently lists 413 recruiting acute heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.