Clinical trials
Acute Heart Failure clinical trials
Below are recruiting acute heart failure clinical trials, each written for real people, not researchers. We’re tracking 418 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07664748Recruiting
Voice check-ins for heart failure monitoring
This study tests whether analyzing your voice during routine check-ins can help monitor heart failure. You'll use a special app or device to talk to a virtual assistant, which may help detect early signs of worsening heart failure.
Milan, ItaAges 18 years+ - NCT07439159Recruiting
Heart ultrasound to predict outcomes in hospitalized heart failure
This study uses a heart ultrasound (echocardiogram) to predict outcomes in people hospitalized for sudden heart failure. If you are receiving IV fluid-removing medication, the results may help your doctors understand your condition better.
IstanbulAges 18 years+ - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07349797Recruiting
Transdermal GFR system to check kidney function in heart failure
This trial tests a sensor placed on the skin to measure kidney function in adults with heart failure. It may help understand how well the kidneys are working without repeated blood draws.
New York, New YorkAges 18 years+ - NCT07029906Recruiting
Testing if beta-blocker side effects are due to expectations
This study tests whether some side effects from beta-blockers are caused by your expectations (the nocebo effect) rather than the drug itself. If you have heart failure and stopped a beta-blocker due to symptoms, this study may help understand your experience and potentially find better ways to manage it.
LondonAges 18 years+ - NCT06992089Recruiting
Pacemaker study for heart failure with low heart rate
This trial tests a special pacemaker setting to help your heart beat faster during exercise. It may improve your ability to be active if you have heart failure with preserved ejection fraction (HFpEF) and a low resting heart rate.
ValenciaAges 18 years+ - NCT06061627Recruiting
LOT-CRT vs standard CRT for heart failure with NICD
This study compares a newer pacing therapy (LOT-CRT) to standard cardiac resynchronization therapy (BiVP) for people with heart failure who have a specific type of electrical delay in the heart (NICD). The goal is to see if the newer method works better.
Nanjing, JiangsuAges 18–80 - NCT06024746RecruitingPhase 3
Finerenone plus SGLT2i for hospitalized heart failure
This trial tests whether adding two heart medicines together (finerenone and an SGLT2 inhibitor) helps people who are in the hospital for heart failure recover better. It may be an option for you if you are currently hospitalized and your heart stress markers are high.
Fairhope, AlabamaAges 18 years+ - NCT06935370RecruitingPhase 3
Testing vicadrostat with empagliflozin for heart failure with weak pump
This trial tests a new drug called vicadrostat combined with another drug, empagliflozin, for people with heart failure and a weak heart pump. It aims to see if this combination helps improve symptoms and outcomes.
Beverly Hills, CaliforniaAges 18 years+ - NCT06827314Recruiting
Treating cardiogenic shock with drug and mechanical support
This trial is testing different approaches (medications and mechanical support) to help people with acute heart failure and cardiogenic shock (a sudden drop in the heart's pumping ability). It looks at how well these treatments work in a network of hospitals to improve outcomes.
Bologna, BolognaAges 18 years+ - NCT06142474RecruitingPhase 3
SGLT2 inhibitors for heart failure patients during ventilator weaning
This trial tests a heart failure medication (SGLT2 inhibitor) to help people with heart failure who are on a breathing machine (ventilator) get better and come off the machine faster. It is for patients with a specific type of heart failure where the heart pumps weakly (EF ≤ 40%).
TaipeiAges 20 years+ - NCT07541768Recruiting
Training Residents to Use Ultrasound for Fluid Assessment
This study teaches medical residents how to use a bedside ultrasound technique called VExUS to check if patients have too much fluid in their body. You'll learn a specific skill that could help you assess patients faster and more accurately.
BernAges Any age - NCT07293923Recruiting
Magenta Elevate™ study for cardiogenic shock
This trial tests a new heart pump called the Magenta Elevate™ to help people whose heart suddenly stops pumping enough blood (cardiogenic shock). It aims to improve blood flow and reduce strain on the heart.
TbilisiAges 40–89 - NCT06597331Recruiting
Heart function study for COPD flare-ups
This study looks at how a COPD flare-up might affect the heart in people who haven't had a heart attack or known heart muscle damage before. It uses a simple heart ultrasound to check for stress-related changes.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT05675345Recruiting
Negative pressure breathing device for sudden low-oxygen breathing failure
This trial studies a continuous negative external pressure device (a “cuirass” that helps breathing) for people with sudden, severe low oxygen levels. It aims to see whether the device improves breathing and oxygen levels without needing immediate intubation.
Brooklyn, New YorkAges 18 years+ - NCT06196086Recruiting
Measuring heart stiffness in heart failure with normal pumping
This study uses a special ultrasound technique to check how stiff the heart muscle is in people with heart failure who have a normal pumping ability (HFpEF). It aims to better understand heart stiffness to help diagnose and manage this condition.
Jinan, ShandongAges 18–80 - NCT03197350Recruiting
Study of heart failure with preserved pumping function
This study looks at people who have heart failure symptoms but whose heart pumping strength is not reduced. Researchers aim to better understand this type of heart failure and compare it with people who have no history of heart disease or heart failure.
BrusselsAges 18–99 - NCT06630923RecruitingPhase 3
Preventing kidney worsening with IV albumin in heart failure
This trial tests if giving a medicine called albumin through a vein can help prevent kidney function from getting worse in people hospitalized with worsening heart failure and liver problems. It may be an option if other treatments haven't worked.
Alexandroupoli, EvrosAges 18–95 - NCT07560436RecruitingPhase 2
Stents for Heart Failure With Normal Pumping
This trial tests whether placing stents in coronary arteries helps patients with heart failure who still have a strong-pumping heart. The study aims to see if improving blood flow to the heart reduces symptoms and improves quality of life.
LondonAges 18 years+ - NCT06465043Recruiting
Understanding Heart Failure When the Heart Stiffens
This study is for people with a type of heart failure called HFpEF, where the heart pumps normally but doesn't relax well. It aims to better understand heart failure through advanced testing, and it includes people who are newly diagnosed or have had a recent hospitalization.
HelsinkiAges 18–85 - NCT06754475Recruiting
Low volume arm HIIT for heart failure patients
This trial tests if short, high-intensity arm exercises can help people with stable heart failure. It looks at safety and improvements in daily function.
Mersin, MersinAges 18 years+ - NCT07496372RecruitingPhase 3
Stem cell injection for advanced heart failure
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07480915Recruiting
Heart failure risk after bypass surgery
This study looks at how to predict major heart problems in people with heart failure who are scheduled for bypass surgery (CABG). It aims to improve risk assessment before the procedure.
Tomsk, Tomsk OblastAges Any age
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Common questions
- Are there clinical trials for acute heart failure?
- Yes. Clin2 currently lists 418 recruiting acute heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.