Clinical trials
Acute Ischemic Stroke From Large Vessel Occlusion clinical trials
Below are recruiting acute ischemic stroke from large vessel occlusion clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07509645RecruitingPhase 3
Testing a new drug with clot removal for severe back-of-the-brain stroke
This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.
Suzhou, AnhuiAges 18 years+ - NCT07516522RecruitingPhase 2
Steroid injection during stroke clot removal surgery
This trial tests whether injecting a steroid (methylprednisolone) directly into brain blood vessels after removing a stroke clot helps reduce brain swelling and improve recovery. You would be eligible if you had a large clot stroke in the front part of your brain that was successfully removed within the past 24 hours.
Xi'an, ShaanxiAges 18–80 - NCT07519044RecruitingPhase 4
GM1 drug added to clot removal for acute stroke
This study tests whether adding a medicine called GM1 to emergency clot-removal surgery helps people recover better from sudden strokes caused by blood clots in major brain arteries. GM1 may protect brain cells from damage during and after the stroke.
Beijing, Beijing MunicipalityAges 18–80 - NCT07552610Recruiting
Sivelestat sodium added to clot removal surgery for stroke
This trial tests whether adding a medication called sivelestat sodium to emergency clot removal surgery (mechanical thrombectomy) can improve outcomes in patients with a specific type of stroke caused by a large blood clot in the front part of the brain. The goal is to see if this combination treatment leads to better recovery.
Weifang, ShandongAges 18–80 - NCT07556068Recruiting
Brain Blood Flow Recovery After Stroke Clot Removal
This study enrolls people who had an acute ischemic stroke (caused by a blood clot) and received emergency treatment to remove the clot. Researchers want to understand why some patients recover well while others don't, by measuring how the brain regulates its own blood flow after treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07594314RecruitingPhase 2/Phase 3
Minocycline after stroke clot removal surgery
This trial tests whether minocycline, an antibiotic, can reduce brain damage when given after successful clot removal surgery for acute stroke. The goal is to see if this medication helps patients recover better.
Wuhan, HubeiAges 18 years+ - NCT07626450Recruiting
Hyperbaric oxygen after stroke clot removal treatment
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help recovery after emergency clot-removal surgery for large blood vessel strokes. The goal is to see if extra oxygen can reduce brain damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+ - NCT06702787Enrolling by invitation
Mechanical thrombectomy for stroke in the Middle East and North Africa
This study collects information from people who had a stroke from a blocked brain artery and were treated with mechanical thrombectomy (a procedure to remove the clot). The goal is to understand how well this treatment works in the Middle East and North Africa.
Alexandria, Alexandria GovernorateAges Any age - NCT06665386Recruiting
Cooling infusion with clot removal for severe stroke
This study tests whether cooling the brain during clot removal (thrombectomy) can improve recovery after a severe stroke caused by a large blood vessel blockage. Researchers will use blood tests to find markers that may predict who benefits most.
Dalian, LiaoningAges 18–80 - NCT03481205Recruiting
Air-transport treatment to protect brain tissue after stroke
This trial studies a protective “conditioning” treatment given during air ambulance transport for people with a suspected large-vessel ischemic stroke. The goal is to reduce further brain injury and preserve more brain tissue while you’re being transported for stroke care.
Iowa City, IowaAges 18–80 - NCT04942041Recruiting
Thrombectomy for large stroke blockages at low-volume centers
This study tests whether using a procedure called mechanical thrombectomy at smaller stroke centers can improve outcomes after a large-vessel stroke. It may help people who have a major artery blockage get timely treatment, with measured effects on complications and survival.
Kristiansand, AgderAges 18–100 - NCT07049692Recruiting
Hyperbaric oxygen after stroke clot removal study
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover better after having a stroke caused by a large clot in the front part of the brain. It is for people who recently had a clot removal procedure and have some remaining disability but are still awake and aware.
Beijing, Beijing MunicipalityAges 35–75 - NCT04517383Recruiting
Sedation after clot-removal brain procedure: which helps recovery
This trial compares different types of calming medicine (sedation) after a procedure to remove a brain blood clot. It aims to see whether post-procedure sedation can improve recovery in people with a serious type of stroke.
ShanghaiAges 18–85 - NCT05198323RecruitingPhase 2
Study drug for people with stroke undergoing clot removal
This Phase 2 trial tests whether the study medicine (LT3001) is safe and improves outcomes for people with an acute ischemic stroke who are getting a procedure to remove a clot (EVT). It aims to help certain patients who have a specific brain scan pattern soon after stroke symptoms start.
Chattanooga, TennesseeAges 18–90 - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Torrance, CaliforniaAges 18–80 - NCT06545591Recruiting
Predicting stroke treatment success with a blood test
This trial studies a blood marker called sTREM to see if it can help predict outcomes after a mechanical clot removal procedure (endovascular thrombectomy) for large-vessel stroke. If you have had a stroke due to a large artery blockage within the last 24 hours and plan to have this procedure, you may be able to join.
Xuzhou, JiangsuAges 18 years+ - NCT06645405Recruiting
AI scan reading for stroke caused by large vessel blockage
This trial tests whether an AI program can better read CT scans to find large blood vessel blockages that cause stroke. If you had a stroke from a blocked large vessel and already had CT scans, the AI may help doctors decide on treatment faster.
Shanghai, Shanghai MunicipalityAges 18–95 - NCT06663631RecruitingPhase 1
Hibernation-like therapy for stroke recovery after clot removal
This trial tests if a hibernation-like therapy can improve recovery after a stroke caused by a large blood clot in the brain. It is for people who are having a stroke and are scheduled for a procedure to remove the clot.
Linyi, ShandongAges 18–80 - NCT06677970RecruitingPhase 3
Blood Pressure Control After Stroke Thrombectomy
This trial tests whether carefully lowering blood pressure after a mechanical clot removal procedure for stroke can improve outcomes. If you've had a large vessel stroke that was successfully treated with thrombectomy, this study will help guide blood pressure management in the recovery period.
Seoul, SeoulAges 20 years+ - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Chicago, IllinoisAges 18–85 - NCT04201964Recruiting
TNK treatment for stroke when blood flow didn’t reopen enough
This trial looks at giving a clot-busting medicine directly into the brain arteries (intra-arterial TNK) when a stroke procedure (thrombectomy) doesn’t reopen the blocked vessel enough. It aims to improve recovery by improving blood flow while checking for safety, especially bleeding risk.
ShenyangAges 18 years+ - NCT04971564Recruiting
Blood inflammation test study in sudden brain oxygen loss
This trial looks at blood “inflammation-related” biomarkers to understand what happens early after certain sudden brain events. It may help doctors predict outcomes and tailor treatment for people like those with stroke types that sometimes need a clot-removal procedure.
Paris, Île-de-France RegionAges 18 years+ - NCT06928675Recruiting
Cell-free DNA in acute stroke
This study looks at how a substance called cell-free DNA in the blood changes in people with a large blood clot causing a stroke. It aims to improve understanding of this condition and might help with future treatments.
BaselAges 18 years+
Hear when a new Acute Ischemic Stroke From Large Vessel Occlusion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acute ischemic stroke from large vessel occlusion?
- Yes. Clin2 currently lists 99 recruiting acute ischemic stroke from large vessel occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke from large vessel occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke from large vessel occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.