Clinical trials
Acute Ischemic Stroke From Large Vessel Occlusion clinical trials
Below are recruiting acute ischemic stroke from large vessel occlusion clinical trials, each written for real people, not researchers. We’re tracking 100 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06155032Recruiting
Clot Removal for Worsening Mild Stroke
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Fuyang, AnhuiAges 18 years+ - NCT06143488Recruiting
Clot removal versus medication for mild stroke with large vessel blockage
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Wuhu, AnhuiAges 18 years+ - NCT06121336Recruiting
Tracking a blood marker to measure stroke recovery
This study is looking at a protein in the blood called brain-derived tau, which may increase after a stroke. By measuring it over time, doctors hope to learn more about how the brain is healing and possibly predict recovery.
Munich, BavariaAges 18 years+ - NCT05832762Recruiting
Clot-buster procedure for blocked neck artery stroke
This trial studies whether an emergency clot-removal procedure through the blood vessels (endovascular treatment) helps people who have a stroke caused by a blocked internal carotid artery in the neck. It compares outcomes in patients treated urgently when imaging shows the blockage is likely the main cause.
Montpellier, FanceAges 18 years+ - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05578300Recruiting
Translating thrombectomy care into real-world practice in Asia-Pacific
This study aims to help endovascular thrombectomy for certain severe strokes work well in everyday hospital care across Asia-Pacific. You may be considered if you’re an adult with a specific type of stroke blocked in a major brain blood vessel.
Linyi, ShandongAges 18 years+ - NCT03737786Recruiting
Sedation with collateral support for stroke clot removal
This trial tests a specific sedation approach, along with support during the procedure, for people having emergency clot removal (mechanical thrombectomy) for a certain type of acute ischemic stroke. It may help make the procedure safer and more effective by improving how patients are managed during endovascular treatment.
Los Angeles, CaliforniaAges 18–110 - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Fairhope, AlabamaAges 18–90 - NCT05051397RecruitingPhase 2
Breathing gas study during clot removal for stroke
This Phase 2 trial tests whether changing breathing gas (CO₂ level) during a mechanical procedure to remove a brain blood clot can improve outcomes for acute ischemic stroke. It may help by protecting the brain during the clot-removal procedure under general anesthesia.
Clermont-FerrandAges 18 years+ - NCT03601702Recruiting
EmboTrap device for large stroke blockages
This trial studies whether a specific clot-removal device (EmboTrap II) works well for acute stroke caused by a large artery blockage. It may help restore blood flow faster in people who have certain scan patterns and can be treated within 12 hours.
MilanAges 18 years+ - NCT06665386Recruiting
Cooling infusion with clot removal for severe stroke
This study tests whether cooling the brain during clot removal (thrombectomy) can improve recovery after a severe stroke caused by a large blood vessel blockage. Researchers will use blood tests to find markers that may predict who benefits most.
Dalian, LiaoningAges 18–80 - NCT03481205Recruiting
Air-transport treatment to protect brain tissue after stroke
This trial studies a protective “conditioning” treatment given during air ambulance transport for people with a suspected large-vessel ischemic stroke. The goal is to reduce further brain injury and preserve more brain tissue while you’re being transported for stroke care.
Iowa City, IowaAges 18–80 - NCT04942041Recruiting
Thrombectomy for large stroke blockages at low-volume centers
This study tests whether using a procedure called mechanical thrombectomy at smaller stroke centers can improve outcomes after a large-vessel stroke. It may help people who have a major artery blockage get timely treatment, with measured effects on complications and survival.
Kristiansand, AgderAges 18–100 - NCT07049692Recruiting
Hyperbaric oxygen after stroke clot removal study
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover better after having a stroke caused by a large clot in the front part of the brain. It is for people who recently had a clot removal procedure and have some remaining disability but are still awake and aware.
Beijing, Beijing MunicipalityAges 35–75 - NCT06545591Recruiting
Predicting stroke treatment success with a blood test
This trial studies a blood marker called sTREM to see if it can help predict outcomes after a mechanical clot removal procedure (endovascular thrombectomy) for large-vessel stroke. If you have had a stroke due to a large artery blockage within the last 24 hours and plan to have this procedure, you may be able to join.
Xuzhou, JiangsuAges 18 years+ - NCT06645405Recruiting
AI scan reading for stroke caused by large vessel blockage
This trial tests whether an AI program can better read CT scans to find large blood vessel blockages that cause stroke. If you had a stroke from a blocked large vessel and already had CT scans, the AI may help doctors decide on treatment faster.
Shanghai, Shanghai MunicipalityAges 18–95 - NCT06663631RecruitingPhase 1
Hibernation-like therapy for stroke recovery after clot removal
This trial tests if a hibernation-like therapy can improve recovery after a stroke caused by a large blood clot in the brain. It is for people who are having a stroke and are scheduled for a procedure to remove the clot.
Linyi, ShandongAges 18–80 - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Chicago, IllinoisAges 18–85 - NCT06677970RecruitingPhase 3
Blood Pressure Control After Stroke Thrombectomy
This trial tests whether carefully lowering blood pressure after a mechanical clot removal procedure for stroke can improve outcomes. If you've had a large vessel stroke that was successfully treated with thrombectomy, this study will help guide blood pressure management in the recovery period.
Seoul, SeoulAges 20 years+ - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Torrance, CaliforniaAges 18–80 - NCT04201964Recruiting
TNK treatment for stroke when blood flow didn’t reopen enough
This trial looks at giving a clot-busting medicine directly into the brain arteries (intra-arterial TNK) when a stroke procedure (thrombectomy) doesn’t reopen the blocked vessel enough. It aims to improve recovery by improving blood flow while checking for safety, especially bleeding risk.
ShenyangAges 18 years+ - NCT04971564Recruiting
Blood inflammation test study in sudden brain oxygen loss
This trial looks at blood “inflammation-related” biomarkers to understand what happens early after certain sudden brain events. It may help doctors predict outcomes and tailor treatment for people like those with stroke types that sometimes need a clot-removal procedure.
Paris, Île-de-France RegionAges 18 years+ - NCT06928675Recruiting
Cell-free DNA in acute stroke
This study looks at how a substance called cell-free DNA in the blood changes in people with a large blood clot causing a stroke. It aims to improve understanding of this condition and might help with future treatments.
BaselAges 18 years+ - NCT06551727Enrolling by invitation
Stroke progression treatment: blood pressure and antiplatelet therapy
This trial tests a combination of blood pressure control and antiplatelet therapy for people whose stroke symptoms are getting worse. It is looking for those without a large brain artery clot or heart-related cause.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke from large vessel occlusion?
- Yes. Clin2 currently lists 100 recruiting acute ischemic stroke from large vessel occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke from large vessel occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke from large vessel occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.