Clinical trials
Acute Ischemic Stroke From Large Vessel Occlusion clinical trials
Below are recruiting acute ischemic stroke from large vessel occlusion clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06878066RecruitingPhase 3
Clot-busting treatment after stroke while on Factor Xa inhibitor
This trial tests a clot-busting drug (thrombolysis) for people who had a stroke while on a Factor Xa inhibitor blood thinner. It aims to see if the drug can still safely break up the clot and reduce disability.
Bærum, GjettumAges 18 years+ - NCT06881420Recruiting
New stroke treatment study for blocked arteries
This study tests a special technique called BASIS to treat strokes caused by a buildup of plaque in the brain's large arteries. It may help people who have had a stroke from this condition and are treated within 72 hours.
Fuzhou, FujianAges 18 years+ - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06940128Recruiting
Ischemic conditioning after stroke clot removal
This trial tests a method called direct ischemic conditioning, which is a gentle way to prepare your brain to better handle the return of blood flow after a stroke. It is for people who have had a large artery blockage in the front part of the brain and have already had a successful procedure to reopen the artery.
Shengyang, LiaoningAges 18 years+ - NCT06941961Recruiting
Brain stimulation therapy after stroke clot removal
This trial tests if a non-invasive brain stimulation technique called iTBS can help people recover motor function after a stroke caused by a large clot in the front part of the brain. It is for patients who had the clot removed successfully with a procedure within 24 hours of symptoms starting.
Changchun, JilinAges 18–85 - NCT06959199Recruiting
Treating stroke beyond 24 hours with artery-opening procedure
This study tests whether opening a blocked large artery in the brain up to 5 days (or even 7 days if symptoms are worsening) after a stroke can improve outcomes. It uses a catheter-based treatment (endovascular therapy) for people who have not responded to standard care and have limited brain damage so far.
Hefei, AnhuiAges 18 years+ - NCT06963489Recruiting
Stroke biobank study for large vessel blockage
This study collects blood and tissue samples from people who had a stroke caused by a blockage in a large artery in the brain. The goal is to learn more about the condition by studying these samples over time.
Wuhu, AnhuiAges Any age - NCT07002476RecruitingPhase 3
Early aggressive cholesterol-lowering after stroke with clot removal
This trial tests whether quickly starting an aggressive cholesterol-lowering treatment after a stroke improves recovery. It is for people who are about to have a procedure to remove a large blood clot from their brain.
ShanghaiAges 18 years+ - NCT07016854Recruiting
Early treatment for blocked carotid artery stroke
This trial tests whether early treatment (using a catheter to open the blocked artery) can help people with a stroke caused by a blockage in the internal carotid artery. The goal is to improve recovery and reduce disability.
Hangzhou, ZhejiangAges 18 years+ - NCT07052045Recruiting
One-stop emergency care for fast stroke treatment
This trial tests a streamlined approach to quickly start endovascular therapy for people having a severe ischemic stroke caused by a blocked large or medium brain artery. It aims to reduce delays and improve recovery by coordinating the care team as soon as you arrive at the hospital.
NurembergAges 18 years+ - NCT07094763Recruiting
Tenecteplase for posterior stroke 4.5-24 hours after onset
This trial tests a clot-busting drug called tenecteplase for people who had a stroke affecting the back part of the brain (posterior circulation). It may be an option if you can get treatment between 4.5 and 24 hours after symptoms started.
HefeiAges 18–100 - NCT07099599Recruiting
Image test for blood flow after stroke treatment
This trial uses a special imaging technique to check if blood flow has fully returned to the brain after a stroke clot is removed. It aims to improve understanding of how well the brain's tiny blood vessels are working after treatment.
Cincinnati, OhioAges 18 years+ - NCT07139301Recruiting
Timing of blood thinners after stroke clot removal in atrial fibrillation
This study aims to find the best time to start blood thinners after emergency clot removal in people with atrial fibrillation who had a stroke. It may help reduce the risk of another stroke or bleeding.
Ma’anshan, AnhuiAges 18 years+ - NCT07139314Recruiting
Timing of blood thinners after stroke clot removal
This trial is testing the best time to start blood thinners (anticoagulation) after emergency stroke treatment in people who have atrial fibrillation. It is for patients who had a certain type of bleeding in the brain after the procedure.
Ma’anshan, AnhuiAges 18 years+ - NCT07141303RecruitingPhase 3
Steroid after stroke clot removal for anterior circulation large vessel occlusion
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
Xi'an, ShaanxiAges 18–80 - NCT07172789Recruiting
Head down position before clot removal for large stroke
This trial tests whether a specific head-down position before a clot removal procedure improves outcomes for people with a large vessel occlusion stroke. It is for patients who have a confirmed blockage and can wait a short time before the procedure.
Shenyang, None SelectedAges 18 years+ - NCT07174505Recruiting
Study of the CONDA Stent Retriever for stroke patients
This trial tests a device called the CONDA Stent Retriever to remove blood clots in people having a severe stroke caused by a blockage in a large brain artery. It may help if you can be treated within 24 hours of symptoms starting and meet specific brain scan and health criteria.
BudapestAges 18–85 - NCT07253181RecruitingPhase 3
Tenecteplase before clot removal for stroke at 4.5-24 hours
This trial tests a clot-busting drug called tenecteplase for people who have a large artery blockage in the front part of the brain and are being transferred to a specialized center for a clot removal procedure. It may help dissolve the clot before the procedure, even if it's been up to 24 hours since symptoms started.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07263308RecruitingPhase 3
Albumin for large artery stroke after clot removal
This trial tests whether giving albumin, a protein naturally found in blood, can improve recovery after a large artery stroke when given along with a procedure to remove the clot. It's for people aged 18-80 who have a stroke from a blockage in the front part of the brain and can get treatment within 24 hours.
Fuyang, AnhuiAges 18–80 - NCT07356284RecruitingPhase 3
Stroke treatment study for blocked arteries with narrowing
This study tests a rescue treatment for people having a major stroke caused by a blocked artery in the brain that also has severe narrowing. If doctors can't fully open the artery with standard clot removal, this study looks at whether additional treatments can help.
Toledo, OhioAges 18–80 - NCT07357987RecruitingPhase 3
Stroke treatment with tenecteplase via artery
This trial tests a clot-busting drug called tenecteplase given directly into the brain artery for people having a moderate stroke caused by a blockage in a medium-sized blood vessel. The goal is to see if it helps improve recovery when given within 24 hours of stroke symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07375966RecruitingPhase 2
Repeated clot-busting drug for stroke with large vessel block
This trial tests if giving a second dose of the clot-busting drug tenecteplase can help people whose stroke symptoms don't improve after the first dose, when a large or medium artery in the brain is still blocked. It may be an option for patients who cannot have a mechanical clot removal procedure.
Shenyang, LiaoningAges 18–80 - NCT07550296RecruitingPhase 2
Second IV Clot-Dissolving Treatment for Major Stroke
This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
Shenyang, None SelectedAges 18–80 - NCT07404852Recruiting
Vagus nerve stimulation for reducing inflammation after stroke
This trial tests whether a non-invasive device that stimulates the vagus nerve can reduce inflammation and brain injury after a stroke caused by a large blood clot.
St Louis, MissouriAges 18–99
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Common questions
- Are there clinical trials for acute ischemic stroke from large vessel occlusion?
- Yes. Clin2 currently lists 99 recruiting acute ischemic stroke from large vessel occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke from large vessel occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke from large vessel occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.