Clinical trials
Acute Ischemic Stroke From Large Vessel Occlusion clinical trials
Below are recruiting acute ischemic stroke from large vessel occlusion clinical trials, each written for real people, not researchers. We’re tracking 100 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07094763Recruiting
Tenecteplase for posterior stroke 4.5-24 hours after onset
This trial tests a clot-busting drug called tenecteplase for people who had a stroke affecting the back part of the brain (posterior circulation). It may be an option if you can get treatment between 4.5 and 24 hours after symptoms started.
HefeiAges 18–100 - NCT07085390Recruiting
Comparing two catheters for stroke clot removal
This study compares two types of catheters (thin tubes) used during a stroke procedure to remove a blood clot. The goal is to see which one works better for clearing blockages in large blood vessels in the brain.
Tampa, FloridaAges 18 years+ - NCT07052045Recruiting
One-stop emergency care for fast stroke treatment
This trial tests a streamlined approach to quickly start endovascular therapy for people having a severe ischemic stroke caused by a blocked large or medium brain artery. It aims to reduce delays and improve recovery by coordinating the care team as soon as you arrive at the hospital.
NurembergAges 18 years+ - NCT07016854Recruiting
Early treatment for blocked carotid artery stroke
This trial tests whether early treatment (using a catheter to open the blocked artery) can help people with a stroke caused by a blockage in the internal carotid artery. The goal is to improve recovery and reduce disability.
Hangzhou, ZhejiangAges 18 years+ - NCT07002476RecruitingPhase 3
Early aggressive cholesterol-lowering after stroke with clot removal
This trial tests whether quickly starting an aggressive cholesterol-lowering treatment after a stroke improves recovery. It is for people who are about to have a procedure to remove a large blood clot from their brain.
ShanghaiAges 18 years+ - NCT06768138RecruitingPhase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration
This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.
NancyAges 18 years+ - NCT06940128Recruiting
Ischemic conditioning after stroke clot removal
This trial tests a method called direct ischemic conditioning, which is a gentle way to prepare your brain to better handle the return of blood flow after a stroke. It is for people who have had a large artery blockage in the front part of the brain and have already had a successful procedure to reopen the artery.
Shengyang, LiaoningAges 18 years+ - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06881420Recruiting
New stroke treatment study for blocked arteries
This study tests a special technique called BASIS to treat strokes caused by a buildup of plaque in the brain's large arteries. It may help people who have had a stroke from this condition and are treated within 72 hours.
Fuzhou, FujianAges 18 years+ - NCT06878066RecruitingPhase 3
Clot-busting treatment after stroke while on Factor Xa inhibitor
This trial tests a clot-busting drug (thrombolysis) for people who had a stroke while on a Factor Xa inhibitor blood thinner. It aims to see if the drug can still safely break up the clot and reduce disability.
Aalborg, AalborgAges 18 years+ - NCT06712004RecruitingPhase 2
Testing a new stroke drug: different doses for people who cannot get standard care
This trial tests a new medication (bevifibatide) to see which dose works best for people having an ischemic stroke who cannot get standard treatments like clot-busting drugs or a procedure to remove the clot. It aims to improve recovery by stopping clots from getting worse.
Guangzhou, GuangdongAges 18–80 - NCT06775782Recruiting
Remote conditioning for moderate stroke from large artery blockage
This trial tests whether a non-invasive arm cuff treatment (remote ischemic conditioning) can help people recover from a moderate stroke caused by a blockage in a major artery. You must start the treatment within 48 hours of your first symptoms.
Xi'an, ShaanxiAges 18–85 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+ - NCT06052969Recruiting
Pulse NanoMED MicroBeads after clot removal for stroke
This trial tests a new treatment called Pulse NanoMED MicroBeads for people who still have a blocked brain artery after a standard clot removal procedure (mechanical thrombectomy). The goal is to see if these tiny beads can clear the remaining blockage and improve blood flow to the brain.
Columbia, South CarolinaAges 18–85 - NCT06702787Enrolling by invitation
Mechanical thrombectomy for stroke in the Middle East and North Africa
This study collects information from people who had a stroke from a blocked brain artery and were treated with mechanical thrombectomy (a procedure to remove the clot). The goal is to understand how well this treatment works in the Middle East and North Africa.
Alexandria, Alexandria GovernorateAges Any age - NCT06658197RecruitingPhase 3
Comparing a new clot-busting drug for severe stroke
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06559241RecruitingPhase 3
Arm or leg cuff treatment for large clot stroke recovery
This trial tests whether a simple, non-invasive treatment (repeated inflation of a blood pressure cuff on your arm or leg) can help people recover better after a stroke caused by a large clot. You must be having a mechanical thrombectomy (clot removal) within 24 hours of your stroke.
Suzhou, AnhuiAges 18 years+ - NCT06548971RecruitingPhase 3
Early antiplatelet after clot-busting for stroke (TREND-IVT)
This trial tests whether giving an antiplatelet medicine (like aspirin) early—within 3 hours of a clot-busting drug—can help prevent another stroke without causing bleeding. It is for people who still have moderate to severe stroke symptoms after the clot-buster and do not have a large artery blockage.
Bengbu, AnhuiAges 18 years+ - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Los Angeles, CaliforniaAges 18 years+ - NCT06383182Recruiting
Study of blood markers after stroke artery treatment
This study looks at how certain proteins in the blood change after a procedure to remove a large blockage in a brain artery. The goal is to better understand recovery after stroke treatment.
ShenyangAges 18–80 - NCT06388148Recruiting
Clot removal for very large strokes
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
Hengyang, HunanAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Jacksonville, FloridaAges 22–85 - NCT06210633Recruiting
Clot removal trial for very large strokes
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
Xiangtan, HunanAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke from large vessel occlusion?
- Yes. Clin2 currently lists 100 recruiting acute ischemic stroke from large vessel occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke from large vessel occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke from large vessel occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.