Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 447 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06556446Recruiting
Clot-busting drug after stroke if on blood thinner
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
InnsbruckAges 18 years+ - NCT07699029Recruiting
Clot removal for stroke in the back of the brain after 24 hours
This study tests a procedure to remove blood clots from large arteries in the back of the brain up to 14 days after a stroke starts. It may help people who have had a stroke more than a day ago and still have significant disability.
Wuhan, HubeiAges 18 years+ - NCT04664933Recruiting
Study to protect the brain during clot-removal stroke treatment
This trial tests a brain-protective approach given through an artery during treatment for an acute ischemic stroke when clot removal (endovascular therapy) is planned. It may help reduce brain injury related to the stroke and procedure.
ShenyangAges 18 years+ - NCT07874594Recruiting
Brain training to improve sleep after a first stroke
This study tests a treatment that may help reduce brain inflammation and improve sleep in people who have had a first stroke and now have trouble sleeping. It uses a non-invasive technique called remote ischemic conditioning, which involves brief, repeated cycles of a blood pressure cuff on the arm.
Chengdu, SichuanAges 18–80 - NCT06806397Recruiting
Brain imaging study of arm weakness after stroke
This study uses a light-based brain scanner (fNIRS) to understand how stroke affects arm movement. It may help find new ways to improve rehab.
MoscowAges 35–70 - NCT06091319Recruiting
Florbetaben imaging for vascular amyloid after heart or brain event
This trial tests whether florbetaben, a special dye, can show amyloid buildup in blood vessels after a recent heart attack, chest pain episode, or stroke. It aims to help doctors better understand and prevent future events.
Ottawa, OntarioAges 18 years+ - NCT06315192Recruiting
Stroke alarm app trial for faster care
This trial tests a smartphone app called Stroke Alarm to see if it helps people who have had a recent stroke, mini-stroke, or have untreated atrial fibrillation get faster care. You may be eligible if you are 50 or older, have a smartphone, and had a relevant event in the last 2 weeks.
GothenburgAges 18 years+ - NCT06253000Recruiting
Heat vs. Freezing for the Back of the Heart
This trial tests two ways to treat the back wall of the heart's left chamber in people with stubborn atrial fibrillation. It compares radiofrequency (heat) and cryoablation (freezing) to see which is safer and works better.
MoscowAges 18–80 - NCT03788512Recruiting
Registry study for recent stroke/TIA with heart artery disease
This study enrolls people who recently had an ischemic stroke or a TIA (a “mini-stroke”) and also have evidence of narrowed heart arteries. It collects information to better understand how brain and heart artery disease occur together and may guide future care.
Beijing, BJAges 18–85 - NCT07375953RecruitingPhase 2
Repeated clot-busting drug for stroke within 3 hours
This trial tests if giving a second dose of a clot-busting drug (tenecteplase) helps people who had a stroke and didn't improve much after the first dose. You must receive the second dose within 4.5 hours of your stroke symptoms starting.
Shenyang, None SelectedAges 18–80 - NCT07323368Recruiting
Perfusion-guided stroke treatment for medium artery blockages
This trial tests a new way to treat strokes caused by blockages in medium-sized brain arteries within 24 hours of symptom onset. It uses brain imaging to select patients who might benefit from a procedure to remove the clot.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03268668Recruiting
Study brain clot makeup and blood markers after stroke
This study looks at the composition of a stroke blood clot and compares it with blood test results to understand treatment response, stroke cause, and prognosis. It may help doctors better predict outcomes and improve care after ischemic stroke.
BordeauxAges 18 years+ - NCT04201964Recruiting
TNK treatment for stroke when blood flow didn’t reopen enough
This trial looks at giving a clot-busting medicine directly into the brain arteries (intra-arterial TNK) when a stroke procedure (thrombectomy) doesn’t reopen the blocked vessel enough. It aims to improve recovery by improving blood flow while checking for safety, especially bleeding risk.
ShenyangAges 18 years+ - NCT07375966RecruitingPhase 2
Repeated clot-busting drug for stroke with large vessel block
This trial tests if giving a second dose of the clot-busting drug tenecteplase can help people whose stroke symptoms don't improve after the first dose, when a large or medium artery in the brain is still blocked. It may be an option for patients who cannot have a mechanical clot removal procedure.
Shenyang, LiaoningAges 18–80 - NCT01364168Recruiting
Study of new stroke patients and what happens next
This study follows people after a first acute ischemic stroke (a blockage-related stroke) to learn what to expect in the days and months after. Your participation could help doctors better understand recovery and outcomes and improve future care.
BerlinAges 18 years+ - NCT03347786RecruitingPhase 1/Phase 2
Verapamil to protect the brain after acute stroke
This trial tests whether verapamil, a common blood-pressure/heart medicine, can help protect the brain after an acute ischemic stroke. It may improve recovery outcomes by supporting the brain’s ability to heal, especially early after stroke symptoms begin.
Atlantic City, New JerseyAges 18–80 - NCT06358313RecruitingPhase 3
Clopidogrel with statins for small vessel stroke
This study tests if combining the blood thinner clopidogrel with either atorvastatin or rosuvastatin (both cholesterol-lowering drugs) works better for people who have had a mild first-time stroke in the small blood vessels of the brain. The goal is to find a safe and effective treatment regimen.
Kafr ash ShaykhAges 18–75 - NCT05983757Recruiting
Clot retrieval for smaller brain artery strokes
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Atlanta, GeorgiaAges 18 years+ - NCT02369770Recruiting
Rehab training for ankle and leg function after a stroke
This study tests a sensory-motor rehabilitation program to improve movement of the ankle and affected leg after a first stroke. It may help people regain safer, more controlled walking and leg movement.
Baltimore, MarylandAges 18–80 - NCT06702787Enrolling by invitation
Mechanical thrombectomy for stroke in the Middle East and North Africa
This study collects information from people who had a stroke from a blocked brain artery and were treated with mechanical thrombectomy (a procedure to remove the clot). The goal is to understand how well this treatment works in the Middle East and North Africa.
Alexandria, Alexandria GovernorateAges Any age - NCT06954155RecruitingPhase 3
Tenecteplase for stroke treatment 24-72 hours after symptoms start
This trial tests if the clot-busting drug tenecteplase can help people with a moderate to severe stroke when given 24 to 72 hours after symptoms began. It aims to see if this later treatment window can improve recovery and reduce disability.
BeijingAges 18 years+ - NCT04971564Recruiting
Blood inflammation test study in sudden brain oxygen loss
This trial looks at blood “inflammation-related” biomarkers to understand what happens early after certain sudden brain events. It may help doctors predict outcomes and tailor treatment for people like those with stroke types that sometimes need a clot-removal procedure.
Paris, Île-de-France RegionAges 18 years+ - NCT07742020Recruiting
Movement therapy comparison for stroke recovery
This study compares two rehabilitation techniques to help people who have had a stroke regain movement in their arm or leg. It aims to find which method works better for improving daily function during the recovery phase.
Lahore, Punjab ProvinceAges 45–65 - NCT06244914Recruiting
Combined brain stimulation for recovery after recent stroke
This trial tests if combining two kinds of gentle brain stimulation can help people recover better after a recent stroke. It's for people who had a clot-caused stroke in the upper part of the brain and still have some weakness on one side.
Tainan, TainanAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 447 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.