Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 447 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05930145Recruiting
Two clot-retrievers versus one for acute stroke treatment
This trial compares using two clot-retrievers at the same time versus using just one to remove the clot in an acute ischemic stroke. It may help find a more effective approach to restore blood flow and improve recovery.
EssenAges 18 years+ - NCT06418698Recruiting
Brain artery calcium and clot removal outcomes
This study looks at whether calcium buildup in brain arteries affects how well clot removal (mechanical thrombectomy) works for stroke patients. You may be able to join if you have a large artery blockage, a CT scan was done, and you are having the clot removal procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06759753RecruitingPhase 2
Aleeto for acute ischemic stroke: a randomized trial
This trial tests a drug called Aleeto in people who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) within the last 72 hours. It aims to see if Aleeto can improve recovery and reduce disability.
BeijingAges 30–80 - NCT06740942Recruiting
Studying nerve system changes after stroke with MRI and blood tests
This study looks at how the nervous system's automatic functions (like heart rate and blood pressure) change after a stroke. It uses MRI scans and blood tests to find patterns that might help doctors better understand and treat these changes.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06728592Recruiting
Emergency stroke care for rapid treatment of ischemic stroke
This trial tests a dedicated emergency stroke unit that provides fast, coordinated care for people with acute ischemic stroke. If you qualify, you may receive clot-busting medication or clot-removal treatment quickly to help reduce brain damage and improve recovery.
Hong KongAges 18–100 - NCT06052969Recruiting
Pulse NanoMED MicroBeads after clot removal for stroke
This trial tests a new treatment called Pulse NanoMED MicroBeads for people who still have a blocked brain artery after a standard clot removal procedure (mechanical thrombectomy). The goal is to see if these tiny beads can clear the remaining blockage and improve blood flow to the brain.
Columbia, South CarolinaAges 18–85 - NCT05247125RecruitingPhase 4
Testing light or melatonin to help brain recovery after stroke
This study looks at whether changing your sleep timing using light therapy or melatonin can improve “brain rewiring” after an ischemic stroke. It mainly focuses on people who arrive very soon after stroke symptoms and who also meet specific safety and sleep/medication requirements.
Saint PetersburgAges 18–80 - NCT06674460RecruitingPhase 3
Edaravone Dexborneol tablet for stroke recovery
This trial tests a new sublingual tablet (Edaravone Dexborneol) to help people recover after a small stroke caused by disease of the small blood vessels in the brain. It aims to see if the drug can improve thinking and daily function.
BeijingAges 30–80 - NCT06658197RecruitingPhase 3
Comparing a new clot-busting drug for severe stroke
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06639360Recruiting
Magnetic stimulation after clot removal for stroke recovery
This trial tests whether adding magnetic brain stimulation (TMS) after clot-removal surgery can help people recover better from a stroke. It is for people who had a moderate-to-severe stroke in the front part of the brain and had the clot removed.
Xi'an, ShaanxiAges 18–80 - NCT06559241RecruitingPhase 3
Arm or leg cuff treatment for large clot stroke recovery
This trial tests whether a simple, non-invasive treatment (repeated inflation of a blood pressure cuff on your arm or leg) can help people recover better after a stroke caused by a large clot. You must be having a mechanical thrombectomy (clot removal) within 24 hours of your stroke.
Suzhou, AnhuiAges 18 years+ - NCT06315231RecruitingPhase 2
Stroke Recovery Thinking Trial for Recent Stroke Patients
This study tests an under-the-tongue tablet (edaravone dexborneol) to help thinking and memory problems that can happen after an ischemic stroke. It may help people who recently had a stroke and now have trouble with attention, memory, or planning.
Fuyang, AnhuiAges 40–80 - NCT06548971RecruitingPhase 3
Early antiplatelet after clot-busting for stroke (TREND-IVT)
This trial tests whether giving an antiplatelet medicine (like aspirin) early—within 3 hours of a clot-busting drug—can help prevent another stroke without causing bleeding. It is for people who still have moderate to severe stroke symptoms after the clot-buster and do not have a large artery blockage.
Bengbu, AnhuiAges 18 years+ - NCT06360120RecruitingPhase 3
Clopidogrel plus a statin for large-vessel stroke recovery
This study tests whether adding clopidogrel (a blood thinner) to atorvastatin or rosuvastatin (cholesterol-lowering drugs) helps people who had a first-time large-vessel ischemic stroke. It aims to find the best way to prevent another stroke.
Kafr ash ShaykhAges 18–75 - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT06494436Recruiting
Real-world study of MicroVention devices for aneurysms or stroke
This study collects information from routine medical care to learn how well MicroVention devices work in real-world settings for people being treated for brain aneurysms or stroke from a blocked artery. Your doctor has already decided to use one of these devices as part of your standard treatment.
Vigo, PontevedraAges Any age - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Los Angeles, CaliforniaAges 18 years+ - NCT06320431RecruitingPhase 3
Clot-busting drug for disabling stroke within 4.5 hours
This trial tests a clot-busting drug called tenecteplase for people having a disabling ischemic stroke (a clot blocking blood flow to the brain). It aims to see if the drug can help improve recovery when given within 4.5 hours of symptoms starting.
Sydney, BarangarooAges 18 years+ - NCT06394180Recruiting
Study of perforations during clot removal for stroke
This trial looks at what happens when a hole (perforation) occurs in a brain artery during clot removal for stroke. It compares patients who had this complication to those who did not, to understand how to better manage it.
BaselAges 18 years+ - NCT06388148Recruiting
Clot removal for very large strokes
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
Hengyang, HunanAges 18 years+ - NCT06297863RecruitingPhase 2
Head-down position to improve blood flow in stroke
This study tests whether lying with your head tilted down 15 degrees can improve blood flow to the brain during a stroke. It is for people who have a clot in the middle cerebral artery and are already getting a procedure to remove the clot.
AvezzanoAges 18 years+ - NCT06292117Recruiting
Genotype-guided antiplatelet therapy for stroke patients
This trial tests whether using a rapid genetic test to choose antiplatelet medication can improve outcomes for people who have had a stroke or mini-stroke. The test checks a gene that affects how your body processes a common antiplatelet drug, so your doctors can pick the safest and most effective medicine for you.
Charlottesville, VirginiaAges 18 years+ - NCT03318432Recruiting
Stroke recovery research registry for people with ongoing symptoms
This study is a registry that enrolls adults who have had a stroke and still have symptoms. It helps researchers learn about stroke recovery over time and may connect you to future stroke research studies.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 447 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.