Clinical trials
Acute Kidney Failure clinical trials
Below are recruiting acute kidney failure clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06587854Recruiting
Study on fluid congestion in acute heart failure patients
This study looks at different patterns of fluid buildup in people with acute heart failure. It aims to understand how these patterns relate to treatment with water pills (diuretics) and may help improve care.
GroningenAges 18 years+ - NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT05540834RecruitingPhase 2
Testing blood-clot guidance for ICU patients with severe lung failure
This Phase 2 trial tests whether using a blood test that shows clotting strength and “clot breakdown time” can help guide treatment for people in the ICU with acute respiratory failure from infection. If you qualify, the team will use these blood results to decide on clot-related therapy and compare outcomes to standard care.
Liverpool, New South WalesAges 18–75 - NCT07215702RecruitingPhase 2
Testing a drug for kidney injury from sepsis in the ICU
This trial tests if a new drug, AZD4144, can help people with sepsis-related acute kidney injury in the ICU. It aims to see if the drug can improve kidney recovery and reduce complications.
Tucson, ArizonaAges 18–80 - NCT06908746Recruiting
Citrate Anticoagulation in Dialysis for Liver and Kidney Failure
This trial looks at whether a blood thinner called citrate is safe and effective in patients who have both kidney and liver failure while on continuous dialysis in the ICU. It may help guide treatment for people with serious organ problems.
Edegem, AntwerpAges 18 years+ - NCT07038356RecruitingPhase 3
Continuing empagliflozin for heart failure patients in hospital
This trial tests whether staying on the medication empagliflozin helps people with heart failure who are hospitalized for worsening symptoms. Empagliflozin is a type of drug called an SGLT2 inhibitor, which helps control blood sugar and protect the heart.
Jena, ThuringiaAges 18 years+ - NCT07400991Recruiting
Restrictive vs liberal fluids for hospitalized heart failure
This trial studies whether drinking less fluid (restrictive) vs. the usual amount (liberal) helps people hospitalized with heart failure. It aims to find out which approach leads to better recovery and fewer symptoms.
HerningAges 18 years+ - NCT06698614Recruiting
Magnetic resonance imaging to study kidney disease
This study uses a special MRI scan to look at the kidneys in people with different kinds of kidney disease, including acute kidney injury, chronic kidney disease, vasculitis, and after a kidney transplant. The goal is to better understand these conditions.
EdinburghAges 18 years+ - NCT05283512Recruiting
IV versus drink fluids to protect kidneys after CT scan
This study compares giving fluids through a vein versus drinking fluids to lower the risk of sudden kidney injury after a CT scan with contrast dye. It focuses on adults with very poor kidney function who are scheduled for an elective CT scan.
Odense C, FynAges 18 years+ - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT02898181Recruiting
Ear cartilage stimulation for sudden heart failure worsening
This trial tests whether a gentle stimulation near your ear (on the tragus, a small ear area) can help people whose heart failure has recently gotten worse while in the hospital. If it works, it may improve symptoms and recovery during this acute phase.
Oklahoma City, OklahomaAges 18–80 - NCT03547414Recruiting
Urine markers to predict kidney injury worsening in septic shock
This study tests whether two substances in urine (TIMP2 and IGFBP7) can help doctors predict which patients with sepsis-related kidney problems will get worse. If these markers work, doctors could identify high-risk patients earlier and treat them more aggressively.
AmiensAges 18 years+ - NCT06972082Recruiting
Ultrasound-guided treatment for kidney injury after heart surgery
This trial tests whether using ultrasound guidance (VEXUS) can help prevent or treat acute kidney injury after heart surgery. If you develop kidney problems in the first two days after your operation, you may be able to join.
Athens, KallitheaAges 18 years+ - NCT05689645RecruitingPhase 2
Drug trial for liver injury or liver failure
This Phase 2 trial tests an injection medicine (F573) to see if it can improve people with liver injury, drug-related liver damage, or liver failure. You may be screened with blood tests, liver stiffness measurements, and possibly symptom checks.
Beijing, Beijing MunicipalityAges 18–60 - NCT06032884Recruiting
Comparing two dialysis methods for severe kidney injury in ICU
This trial compares two ways to filter blood (intermittent hemodialysis and continuous renal replacement therapy) for patients in the intensive care unit with severe acute kidney injury. It aims to find which method works better for critically ill patients.
BobignyAges 18 years+ - NCT06525623Recruiting
Early albumin for kidney injury in cirrhosis
This study tests whether giving a common fluid (albumin) early can help protect the kidneys in people with advanced liver disease who have a sudden kidney injury. It aims to see if this simple treatment can improve recovery and prevent the need for dialysis.
Boston, MassachusettsAges 18 years+ - NCT06917053Recruiting
Ultrasound to predict kidney injury after trauma
This study tests whether a special ultrasound with contrast agent can help predict if you might develop acute kidney injury after a serious trauma. It focuses on patients in the ICU who have had a major injury and received blood products.
LondonAges 18 years+ - NCT07484009Recruiting
ReDS-guided fluid removal for heart failure patients
This trial tests if using a wearable monitor (ReDS) to guide fluid removal helps people hospitalized for heart failure. The goal is to find the right amount of fluid to remove so patients feel better and stay out of the hospital.
Madrid, MadridAges 18 years+ - NCT06307652RecruitingPhase 3
Testing a new heart failure and kidney treatment combo
This study tests a new combination of two medicines (balcinrenone and dapagliflozin) for people with heart failure and reduced kidney function. The goal is to see if this combination helps improve heart and kidney health better than current treatments.
Alexander City, AlabamaAges 18–130 - NCT06372444Recruiting
Kidney injury in severe infections study
This study looks at how severe infections like sepsis can hurt the kidneys. By using special scans (PET-CT), researchers hope to better understand why this happens, which could lead to better treatments.
UppsalaAges 30 years+ - NCT06857630Recruiting
Hemoglobin levels and kidney injury in emergency surgery
This trial looks at whether a patient's hemoglobin level (a measure of red blood cells) before emergency surgery can help predict the risk of acute kidney injury afterward. It aims to find if early detection can prevent kidney damage.
SamsunAges 18–80 - NCT04033224Recruiting
Blood-filter treatments for ICU patients with kidney and organ failure
This trial tests a specific type of blood-filter treatment in critically ill ICU patients who have acute kidney injury and/or failure of other organs. It aims to see whether these filters can improve care by supporting kidney function and/or calming harmful inflammation.
Empoli, FirenzeAges Any age - NCT07626710Recruiting
How Heart Valve Replacement Affects Kidney Function
This study looks at whether a minimally invasive heart valve procedure (TAVI) affects how well your kidneys work. Researchers will track your kidney function before and after the procedure using blood tests to understand any changes.
Roma, RMAges 18 years+
Hear when a new Acute Kidney Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acute kidney failure?
- Yes. Clin2 currently lists 125 recruiting acute kidney failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute kidney failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute kidney failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.