Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05106270Recruiting
Atrial pressure changes around a heart procedure for atrial fibrillation
This trial studies how changing pressure in the heart’s upper chamber before and after a combined heart procedure affects outcomes in people with atrial fibrillation. It may help guide safer, more effective care for patients who need left atrial appendage closure (a way to reduce stroke risk).
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07617974Recruiting
Heart valve changes in atrial fibrillation patients
This study looks at how atrial fibrillation (a common heart rhythm problem) affects the tricuspid valve—one of your heart's four valves. Researchers will use special ultrasound imaging to understand these changes and help improve future treatment.
Milan, MilanAges 18 years+ - NCT07002450Recruiting
CT scan to check for clots before heart shock therapy
This trial uses a CT scan of the left atrium to check for blood clots before a procedure called cardioversion (an electric shock to restore normal heart rhythm). The goal is to see if the CT scan can safely replace other imaging methods in the emergency department, helping to speed up treatment.
Hershey, PennsylvaniaAges 18 years+ - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT04298723Recruiting
Left atrial appendage closure vs blood thinners after brain bleed
This trial compares a procedure that blocks a heart blood-choke point (the left atrial appendage) versus taking blood thinners by mouth. It is for people with atrial fibrillation who have had a brain bleed and may be safer avoiding long-term blood thinners.
Mannheim, Baden-WurttembergAges 18 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT05951101Recruiting
Device to close an irregular heartbeat heart pocket safely
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
Parkville, VictoriaAges 18 years+ - NCT06007872Recruiting
Heart device implant using ultrasound probe inside the heart
This trial studies a procedure to implant a Watchman device using a tiny ultrasound probe placed inside the heart, avoiding a probe in the throat. It may help patients with atrial fibrillation who need to reduce stroke risk.
Cleveland, OhioAges 18 years+ - NCT06436924Recruiting
Safety of high-volume day procedures for left atrial appendage occlusion
This trial studies whether having many left atrial appendage closure (LAAO) device implant procedures on the same day by one doctor is safe and effective. If you are scheduled for this procedure, you may be able to join.
Birmingham, AlabamaAges 18 years+ - NCT07018648Recruiting
Testing a wearable heart monitor for rhythm problems
This trial tests a chest belt that works with your smartphone to track heart rhythms. It may help if you have or might have an irregular heartbeat.
Olomouc, CzechiaAges 18 years+ - NCT07196176Recruiting
Heart rhythm test registry at University Hospital Düsseldorf
This registry collects information from people who have had or are scheduled to have a heart rhythm test or a procedure to restore a normal heartbeat at University Hospital Düsseldorf. It helps doctors understand more about heart rhythm problems and treatments over time.
DüsseldorfAges 18 years+ - NCT07353775Recruiting
Heart procedure using imaging and pulsed energy
This trial uses a special imaging tool inside the heart to guide a new type of energy (pulsed field) to treat a specific area in the heart that can cause atrial fibrillation (an irregular heartbeat). It may help people with paroxysmal or persistent atrial fibrillation who need a procedure called CTI ablation.
BeijingAges 18 years+ - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT07388108Recruiting
Predicting heart rhythm problems after heart surgery
This trial studies whether measuring how the upper chambers of the heart work together can help predict dangerous heart rhythms after heart surgery. If you are in normal heart rhythm and not having mitral valve surgery, this study may help doctors better prevent complications.
Mendoza, MendozzAges 18–80 - NCT07081711Recruiting
Testing new heart MRI technology in volunteers
This study is testing a new way to take pictures of the heart using MRI. It is looking for healthy volunteers to help make sure the technology works correctly.
Cleveland, OhioAges 18 years+ - NCT04703166Recruiting
iPredict study for atrial heart muscle changes over time
This study tracks how “atrial myopathy” (changes in the heart’s upper chambers) develops over time in people with atrial fibrillation or higher heart-risk. It uses special heart MRI pictures and regular follow-up to better predict progression, which may help future care planning.
New Orleans, LouisianaAges 18–79 - NCT05654272Recruiting
Testing CIRC imaging technology for people with heart problems
This study is developing and testing CIRC technologies using heart imaging. You may be able to join if you’re an adult with cardiovascular (heart) disease and can safely have the MRI scans.
Cleveland, OhioAges 18 years+ - NCT07236398Enrolling by invitation
Modified left atrial maze procedure for atrial fibrillation
This trial tests a modified maze procedure to treat atrial fibrillation during heart surgery. It may help patients with AFib who are already scheduled for cardiac surgery.
Toulouse, French (France)Ages 18 years+ - NCT06061757Recruiting
Combining 4D-ICE and TEE imaging for heart closure
This trial tests a new imaging method (4D-ICE) used alongside a standard ultrasound (TEE) during a heart procedure to close the left atrial appendage, a small pouch in the heart where clots can form in people with atrial fibrillation. The goal is to see if the new method makes the procedure safer and more precise.
Overland Park, KansasAges 18–80 - NCT03445949RecruitingPhase 4
Best blood-thinner plan after a left heart device procedure
This trial compares which two medicines work best after a device closes off a part of the heart called the left atrial appendage. It may help reduce stroke risk while balancing bleeding risk after your procedure.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT04800913Recruiting
Imaging tests during left atrial appendage closure
This study looks at how different imaging tests can help guide a procedure that closes off the left atrial appendage to reduce stroke risk. It may help doctors choose the safest approach during the procedure.
BudapestAges 18 years+ - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT07125417RecruitingPhase 4
Blood thinner comparison after left atrial appendage closure
This study compares two approaches after a left atrial appendage closure (LAAC) procedure: taking no blood thinner versus taking just one antiplatelet medication. It aims to see which option is safer for people with atrial fibrillation who are at risk for bleeding.
Nagoya, Aichi-kenAges Any age - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 546 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.