Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07468123Enrolling by invitation
Estimating Atrial Fibrillation Risk With a Handheld ECG
This trial uses a simple, handheld ECG device (like a small card) to check your risk for atrial fibrillation, a common irregular heartbeat. You'll record short heart tracings at home, and the study team will review them to find hidden risk factors.
Boston, MassachusettsAges 18–90 - NCT02699957Recruiting
Left Atrial Appendage Closure Registry Study
This study tracks patients who have a minimally invasive procedure to close off a small pouch in the heart called the left atrial appendage. The procedure aims to reduce stroke risk, and this registry collects information about how patients do after the procedure.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06157437Recruiting
Focal pulse ablation for atrial flutter
This study tests a new device that uses focused pulses of energy to treat a common type of fast heartbeat called typical atrial flutter. It aims to see if this approach is safe and effective for people who have had at least one episode in the past 6 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07492524Recruiting
Better care for older adults with AF and heart failure in rural China
This trial tests a new way to manage care for older patients with atrial fibrillation and heart failure living in rural areas. It uses village doctors and telemedicine to help monitor and treat these conditions together.
Yancheng, DongtaiAges 65–80 - NCT06067438RecruitingPhase 2
Amiodarone to Prevent Irregular Heartbeat After Esophageal Cancer Surgery
This trial tests if amiodarone, a medication that helps keep your heart rhythm steady, can prevent a type of irregular heartbeat called atrial fibrillation after surgery to remove part of your esophagus. If you are having this surgery (called minimally invasive esophagectomy or MIE) for cancer or other esophagus problems, you may be able to join.
Portland, OregonAges 18 years+ - NCT07187570RecruitingPhase 3
Dapagliflozin to prevent atrial fibrillation recurrence after cardioversion
This trial tests if the diabetes drug dapagliflozin can lower the chance of atrial fibrillation (an irregular heartbeat) coming back after a procedure called electrical cardioversion, which uses a shock to restore a normal heart rhythm. If you have AF and are scheduled for cardioversion, you may be able to join.
LinköpingAges 55 years+ - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT05062239Recruiting
Statin use after valve surgery to prevent heart rhythm trouble
This study looks at whether taking statin medicines around the time of surgical aortic valve replacement can lower the chance of a common post-surgery heart rhythm problem called atrial fibrillation. It also compares statin-related factors in people who are at the time of surgery in normal rhythm and not on strong rhythm-stabilizing medicines.
OdenseAges 60–95 - NCT06548269Recruiting
Assessing stroke recovery in patients with atrial fibrillation
This study watches how people recover from a recent stroke caused by a heart rhythm problem called atrial fibrillation (or AFib). It aims to find better ways to predict recovery and guide future care.
Jinan, ShandongAges 18 years+ - NCT07262255Recruiting
Watchman FLX Pro heart device study in Europe
This study tracks people with atrial fibrillation (an irregular heartbeat) who get the WATCHMAN FLX Pro device to reduce stroke risk. It collects real-world data on how well the device works and how safe it is.
AarhusAges 18 years+ - NCT06405750Recruiting
Study of the left atrial appendage during open-heart surgery
This study looks at a part of the heart called the left atrial appendage during open-heart surgery. It aims to learn more about heart rhythm problems and blood clots, which may help improve future treatments.
CopenhagenAges 18 years+ - NCT05712200RecruitingPhase 3
Abelacimab for atrial fibrillation when blood thinners aren’t suitable
This Phase 3 study tests whether abelacimab can prevent stroke and other blood-clot problems in people with atrial fibrillation (or atrial flutter) who cannot safely take usual mouth blood thinners. It also looks at safety, especially bleeding risk.
Birmingham, AlabamaAges 65 years+ - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT05549752RecruitingPhase 3
Flecainide vs amiodarone to treat fast heart rhythm in ER
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
AthensAges 18–85 - NCT06005233Recruiting
Smartwatch heart monitoring after unexplained stroke
This trial uses a smartwatch to look for hidden atrial fibrillation (an irregular heart rhythm) in people who have had a stroke or TIA with no known cause. It could help find the reason for the stroke and guide treatment to prevent another one.
MunichAges 40 years+ - NCT07343895Recruiting
Atrial fibrillation screening in people with high NT-proBNP
This study is checking people over 40 who have a higher-than-average heart stress marker (NT-proBNP) to see if they have undiagnosed atrial fibrillation. You'll use a smartphone to track your heart rhythm at home.
TromsøAges 40 years+ - NCT06735534Recruiting
Repeat ablation for persistent atrial fibrillation with pulsed field
This trial tests a newer type of ablation (pulsed field ablation) for people with persistent atrial fibrillation who have already had one ablation. The goal is to see if it can fix the heart rhythm problem again.
Mobile, AlabamaAges 18 years+ - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT06833138Recruiting
Pacing vs medication for heart rate control in AF with heart failure
This trial tests whether a procedure that regulates your heart rhythm (pacing) works better than medication for people who have permanent atrial fibrillation, heart failure with a normal pumping strength, and were hospitalized for heart failure in the past year.
AalstAges 18 years+ - NCT07611019Enrolling by invitationPhase 2/Phase 3
Colchicine to prevent heart rhythm problems after heart bypass surgery
This study tests whether taking colchicine (a common anti-inflammatory medication) before and after bypass heart surgery can prevent atrial fibrillation—an irregular heartbeat that sometimes occurs after surgery. Researchers hope this simple treatment might reduce complications and improve recovery.
TaipeiAges 20 years+ - NCT07501299Recruiting
HeartBeam ECG Registry for heart monitoring
This registry collects ECG data from people who are already getting an ECG for their heart health. It uses a device called HeartBeam to see if it works as well as the standard ECG machine.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06486636Recruiting
Pericardiotomy in heart surgery
This trial tests whether opening the sac around the heart (pericardiotomy) during certain heart surgeries can help prevent future heart rhythm problems. It may be an option for people having surgery on the main artery from the heart, heart valves, or heart arteries.
New York, New YorkAges 18 years+ - NCT07621055Recruiting
AI software to guide heart rhythm ablation treatment
This study tests new AI software (Volta AF-Xplorer II) that helps doctors guide catheter ablation—a procedure to treat irregular heartbeats like atrial fibrillation. The software may help doctors perform the procedure more effectively and safely in real-world settings.
MarseilleAges 18 years+ - NCT05539040Recruiting
Testing why certain heart signals trigger atrial fibrillation
This trial studies abnormal electrical signals in the right upper heart chamber and how they relate to atrial fibrillation (AF). It may help improve how doctors target AF treatment during catheter ablation for people who have AF symptoms.
LondonAges 18–85
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 546 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.