Clinical trials
Back Pain clinical trials
Below are recruiting back pain clinical trials, each written for real people, not researchers. We’re tracking 390 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07298941RecruitingPhase 2
Sleep treatment to help with chronic low back pain
This study tests if improving sleep can help people with chronic low back pain feel better and cope with pain. It involves a sleep-focused treatment program and looks at how it affects your overall well-being.
Charlottesville, VirginiaAges 18 years+ - NCT07690449Recruiting
CT signs of nerve irritation in sciatica
This study looks at three specific signs on a CT scan that may show nerve-root irritation in people with sciatica. It only includes patients who are already scheduled for a CT-guided nerve injection to treat their pain.
Nice, Alpes MaritimesAges 18 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT07040397Recruiting
Massage therapy study for lower back pain
This study tests whether an electronic approach to massage therapy can help relieve lower back pain. It may be an option if you have persistent lower back pain and haven't used pain medications recently.
Rochester, MinnesotaAges 18 years+ - NCT04631133Recruiting
Study of outcomes after surgery using the LISA implant
This study follows adults who get back surgery using the LISA implant to see how well they do afterward and how outcomes change over time. It focuses on people whose long-term, non-surgical care did not relieve low-back pain from specific age-related disc changes.
SilkeborgAges 18 years+ - NCT05504499Recruiting
Test a new implant for low back pain with mild narrowing
This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.
Santa Rosa, CaliforniaAges 18 years+ - NCT05986370Recruiting
Study on back pain and spinal manipulation
This trial tests whether spinal manipulation therapy (a type of hands-on treatment) can help people with long-term low back pain. It also compares their results to healthy volunteers of the same age and sex.
Trois-Rivières, QuebecAges 18–60 - NCT07860697Recruiting
MRI study of back pain and spine changes
This study looks at MRI images of the lower back to see how body fat, back muscles, and small spine joints relate to long-term back pain. It may help doctors understand back pain better and improve future treatments.
Istanbul, IstanbulAges 18–75 - NCT07807839Recruiting
Back pain study: testing a blood protein linked to MRI findings
This study looks at how a protein in your blood (called BDNF) relates to the severity of your lower back condition, as seen on MRI. It may help doctors better understand and treat back pain in the future.
Daegu, DaeguAges 20–80 - NCT07802951Recruiting
How doctors, physios, and patients view low back pain care
This study interviews general practitioners, physiotherapists, and patients with low back pain to understand how they make care decisions together. The goal is to improve teamwork and communication in primary care.
Woluwe-Saint-Lambert, Brussels CapitalAges 18–100 - NCT07795697Recruiting
Remote rehab after spine surgery
This trial tests whether doing physical therapy at home using video calls or an app helps you recover as well as in-person rehab after spine surgery. It could make it easier for you to get the care you need without traveling.
KuopioAges 20–85 - NCT07790328Recruiting
Long-term safety of the IntraSPINE implant for low back pain
This study checks how safe and effective the IntraSPINE implant is over time for people with low back pain from degenerative discs. The implant is placed in your spine to support it, and this trial helps see if it continues working well for years.
SaranAges 18 years+ - NCT07776366Recruiting
Study of disc protein levels and disc wear
This study looks at a protein called periostin in the discs of the lower back to see if it relates to how worn down the discs are, which might help improve future treatments.
Daegu, DaeguAges 20–80 - NCT07776379Recruiting
Predicting recovery with BDNF blood levels in chronic low back pain
This study looks at whether a protein in your blood, called BDNF, can help predict how well you might do with chronic low back pain. By participating, you may help doctors better understand and treat this condition.
Daegu, DaeguAges 20–80 - NCT07724847Recruiting
Validating new criteria for diagnosing axial spondyloarthritis
This study aims to confirm new classification criteria for axial spondyloarthritis, a type of inflammatory arthritis affecting the spine and sacroiliac joints. Participants with chronic back pain lasting at least 3 months and starting before age 45 will undergo a series of tests to see if these new criteria better identify the condition.
Beijing, Beijing MunicipalityAges 18–45 - NCT07712406Recruiting
Nerve block for lower back pain from nerve entrapment
This trial tests whether a nerve block can help people with chronic lower back or buttock pain caused by a trapped nerve near the hip bone. You may be eligible if you have had this pain for at least 3 months and it did not get better with other treatments.
Gaziosmanpaşa, IstanbulAges 18–75 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT07595718Recruiting
Using health data and AI to predict major diseases
This study uses your health information and artificial intelligence to help predict the onset of major diseases. By joining, you could help improve early detection and prevention for conditions like diabetes, heart disease, and cancer.
Seoul, Seoul Special CityAges 30–65 - NCT07590050Recruiting
Catgut Embedding for Lower Back Pain and Blood Stasis
This trial tests catgut embedding (a traditional acupuncture technique using absorbable material) to treat chronic lower back pain caused by spine wear-and-tear, particularly for patients whose condition matches a traditional medicine pattern called 'blood stasis.' The goal is to see if this approach relieves pain and improves movement.
Ho Chi Minh City, Ho Chi Minh CityAges 18–65 - NCT07561489Enrolling by invitation
Study of OsteoPearl Implants for Spine Fractures
This study observes how a biological implant called OsteoPearl helps people recover from recent spine fractures in the mid or lower back. Researchers will track your pain relief and ability to function over time after a minimally invasive procedure to stabilize the fracture.
Williamsville, New YorkAges 50 years+ - NCT05641948Recruiting
Tested nerve ablation plus brain scans for ongoing back pain
This trial studies a procedure called radiofrequency denervation to reduce long-lasting, mostly “pain-from-joints/structures” low back pain, and it uses brain imaging to understand what changes during treatment. It may help people who already showed they respond well to a similar diagnostic nerve block.
Aberdeen, ScotlandAges 18 years+ - NCT06751160Recruiting
Dry needling vs. soft tissue massage for tight hamstrings
This study compares two treatments—dry needling and soft tissue massage—to see which works better for relieving tight hamstring muscles in people with low back pain.
Lahore, Punjab ProvinceAges 20–40 - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55 - NCT06715085RecruitingPhase 4
PRGF injections for chronic low back pain
This trial tests whether injections of a blood-based treatment called PRGF can help people with long-term low back pain caused by worn discs. It is for those who haven't gotten relief from standard treatments like medication.
Vitoria-Gasteiz, AlavaAges 18 years+
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Common questions
- Are there clinical trials for back pain?
- Yes. Clin2 currently lists 390 recruiting back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.