Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06132178RecruitingPhase 2
Psilocybin and rTMS for hard-to-treat depression
This study tests whether a combination of psilocybin (a psychedelic substance) and transcranial magnetic stimulation (rTMS, a noninvasive brain stimulation) can help people with treatment-resistant depression. It involves daily visits to the research center for about 2 weeks.
Austin, TexasAges 22–65 - NCT06150560RecruitingPhase 3
Blood pressure medicine study for people with repaired coarctation of the aorta
This trial tests a type of blood pressure medicine (an angiotensin-II receptor blocker) to see if it can help prevent changes in the heart's structure. It is for people who have had surgery for a coarctation of the aorta and now have mild to moderate high blood pressure.
Rochester, MinnesotaAges 18 years+ - NCT06152705Recruiting
fMRI-Guided vs. Standard Brain Stimulation for Depression
This study compares two types of repetitive transcranial magnetic stimulation (rTMS) to treat depression. One type uses a brain scan (fMRI) to guide the treatment, while the other uses a standard approach. It may help people whose depression hasn't improved with medication.
Ottawa, OntarioAges 18 years+ - NCT03517579Recruiting
Personalized treatment for Graves and certain thyroid cancers
This trial tests a personalized approach to treat thyroid disorders, either Graves’ disease or certain thyroid cancers that may need radioactive iodine treatment. It may help by matching treatment to your specific test results and needs.
Baltimore, MarylandAges 21–65 - NCT06113016RecruitingPhase 2
Preventing frailty with fisetin and exercise in breast cancer survivors
This study tests whether adding a supplement called fisetin to an exercise program can help prevent frailty in women who have finished chemotherapy for early-stage breast cancer. If you are postmenopausal, have completed chemo within the last year, and can walk a certain distance, you may qualify.
Alhambra, CaliforniaAges Any age - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT06122064Recruiting
Tool to help lung cancer patients decide on adjuvant treatment
This study is testing a tool to help you and your doctor make decisions together about whether to have extra treatment after surgery for non-small cell lung cancer (stage 1B or higher). It only includes patients at Mayo Clinic in Rochester who are eligible for that extra treatment.
Rochester, MinnesotaAges 18 years+ - NCT06110897Recruiting
Resistance Exercise for Depression Trial
This study tests whether resistance exercise (like lifting weights) can help reduce depression symptoms. If you have major depression and are not already doing regular resistance training, you may be able to join.
Ames, IowaAges 18–65 - NCT06105684RecruitingPhase 2
Low-dose capecitabine for advanced breast cancer
This trial tests a lower dose of the chemotherapy drug capecitabine in people with advanced breast cancer that is HER2 negative. It aims to see if this gentler dose works well, especially for older or frailer patients who may have more difficulty with standard treatment.
Birmingham, AlabamaAges 60 years+ - NCT06112067Recruiting
Brain implant for severe mental health conditions
This trial tests a brain implant called deep brain stimulation (DBS) for people with severe mental health conditions that have not improved with usual treatments. The goal is to see if it can reduce symptoms and improve quality of life.
ShanghaiAges 18–65 - NCT06121505RecruitingPhase 2
Low-dose radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding low-dose radiation and a type of targeted radiation (SBRT) to a combination of immunotherapy (sintilimab) and chemotherapy works better than immunotherapy and chemotherapy alone for people with advanced squamous cell lung cancer.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05292521Recruiting
Quality-of-life program to help early lung cancer decisions
This trial tests a quality-of-life support program meant to help people with early-stage lung cancer think through their treatment choices. It may help you feel more informed and more confident about deciding between treatments like surgery and SBRT.
Buffalo, New YorkAges 18 years+ - NCT06084338RecruitingPhase 2
Focused Radiation Therapy Without Hormone Therapy for Advanced Prostate Cancer
This trial tests whether giving focused radiation to many cancer spots (SBRT) can work without using testosterone-blocking hormone therapy. It is for men whose prostate cancer has spread and is no longer responding to low testosterone, and who have already tried one of the newer hormone drugs.
West Los Angeles, CaliforniaAges 18 years+ - NCT06091566Recruiting
Nerve stimulation device for overactive bladder and bowel
This study tests a new kind of nerve stimulation device that is inserted into the vagina to help control bladder and bowel problems. It may reduce urgent trips to the bathroom, leaking, and other symptoms of overactive bladder or bowel dysfunction.
AarhusAges 18 years+ - NCT06100705RecruitingPhase 2
Immunotherapy plus testosterone for advanced prostate cancer
This study combines an immunotherapy drug called sipuleucel-T (which boosts your immune system to fight cancer) with a high-dose testosterone treatment called bipolar androgen therapy. The goal is to see if this combination can help men with advanced prostate cancer that is not responding to usual hormone therapy.
New Haven, ConnecticutAges 18 years+ - NCT06085742RecruitingPhase 2
CMC chemotherapy for early stage breast cancer
This trial tests a chemotherapy combination (CMC) for people with early-stage, hormone receptor-positive, HER2-negative breast cancer who have a high risk of recurrence. It aims to understand if this oral regimen is effective and tolerable.
Chicago, IllinoisAges 18 years+ - NCT06103760RecruitingPhase 4
Esketamine for hard-to-treat depression
This study tests whether esketamine, a nasal spray for depression, can help adults whose depression has not improved with at least two other antidepressants. Participants continue their current treatment while receiving esketamine.
St Leonards, New South WalesAges 18–65 - NCT06093204Recruiting
Ultra-processed foods and eosinophilic esophagitis study
This study looks at how certain chemicals from ultra-processed foods (like packaged snacks and sodas) might trigger eosinophilic esophagitis, a food allergy condition. It will compare people with the disease to healthy volunteers of the same age and sex.
Naples, NaplesAges 3–65 - NCT06083844RecruitingPhase 2
Keytruda + Avastin + chemo for ovarian cancer with minimal remaining disease
This trial tests a combination of three drugs—pembrolizumab (Keytruda, an immunotherapy), bevacizumab (Avastin, a blood-vessel blocker), and oral cyclophosphamide (a chemotherapy pill)—for women with high-grade ovarian cancer who have only tiny bits of disease left after finishing their initial treatment.
New York, New YorkAges 18 years+ - NCT06088303Recruiting
Improving PTSD treatment through better communication
This study tests if improving how you talk with your doctor can make PTSD treatment work better. You can join if you have PTSD and have been on stable medications for at least 4 weeks.
Boston, MassachusettsAges 18 years+ - NCT06086366Recruiting
Brain scan study for depression after COVID-19
This study uses brain scans to understand depression that starts soon after COVID-19. Researchers want to see if there are changes in brain chemistry related to depression, and you may help find new treatment targets.
Toronto, OntarioAges 18–75 - NCT03665831Recruiting
Deep TMS for depression and memory problems in older adults
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Toronto, OntarioAges 60 years+ - NCT05490225Recruiting
Test device to make dialysis fistulas easier to stick safely
This trial tests a small implant device that can make dialysis fistulas easier to access with needles when normal needle access is too difficult or risky. It may help reduce painful failed attempts and needle-related complications for people with certain types of fistulas.
Dothan, AlabamaAges 18 years+ - NCT05560113Recruiting
Study uses brain stimulation to disrupt fear memory in PTSD
This study tests a brain stimulation approach to affect how fear memories “stick” after they are formed. If you have PTSD, it may help reduce fear-related learning, but you must meet several safety and health criteria.
Atlanta, GeorgiaAges 18–65
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,350 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.