Clinical trials
Cancer Surgery clinical trials
Below are recruiting cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 860 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07237126Recruiting
Single-port robotic surgery for stomach cancer
This trial is testing a newer, less invasive robotic surgery technique that uses just one small incision to remove stomach cancer. It may offer faster recovery and less pain compared to traditional surgery.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06307548RecruitingPhase 1/Phase 2
Image-guided surgery and light therapy for colorectal cancer
This trial tests a special dye that helps surgeons see tumors more clearly during surgery, followed by a light therapy to destroy any remaining cancer cells. It is for people with advanced or returning colorectal cancer who are already scheduled for surgery.
Buffalo, New YorkAges 18 years+ - NCT05806515RecruitingPhase 2
Carboplatin before surgery for high-risk BRCA prostate cancer
This trial tests giving the chemotherapy drug carboplatin before surgery to treat people with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene change. The goal is to shrink or control the cancer before an operation and improve outcomes.
Anchorage, AlaskaAges 18 years+ - NCT06292286Recruiting
Second surgery for recurrent ovarian cancer that responds to platinum
This trial tests whether having a second surgery after initial treatment can help people with ovarian cancer that came back but still responds to platinum-based chemotherapy. It may offer another option to remove remaining tumors and delay further treatments.
Hong KongAges 18 years+ - NCT04510597RecruitingPhase 3
Immunotherapy plus surgery versus immunotherapy alone for kidney cancer
This study tests whether adding surgery to remove the kidney improves outcomes compared with continuing immunotherapy without surgery. It is for people with metastatic kidney cancer whose disease has not worsened after initial immunotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06477991Recruiting
No surgery after immunotherapy for MSI-H colorectal cancer
This trial is studying whether some people with a specific type of advanced colorectal cancer (MSI-H/dMMR) might be able to skip surgery after immunotherapy. Doctors will use a blood test (MRD monitoring) to track the cancer, and then decide whether to keep an eye on it or operate.
Kunming, YunnanAges 18–75 - NCT07745881Recruiting
Pain relief after lung cancer surgery
This trial tests a nerve block that may reduce pain after surgery for lung cancer. It's a technique that numbs a specific area in the back to help you feel more comfortable during recovery.
Nanjing, JiangsuAges 18–80 - NCT07364305RecruitingPhase 2
Hepatic artery infusion + immunotherapy for advanced bile duct cancer
This trial tests combining a liver-directed chemotherapy infusion (HAIC) with immunotherapy to shrink advanced bile duct cancer that cannot be removed surgically. The goal is to slow tumor growth and improve survival.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06519500Recruiting
Growing tumor models from gastrointestinal neuroendocrine tumor surgery
This study takes tumor tissue from people having surgery for a certain type of gut or pancreas cancer (neuroendocrine tumors). The tissue is used to grow tiny 3D models called organoids in the lab, which can help researchers learn more about the tumor and find better treatments.
RomeAges 18 years+ - NCT06798922RecruitingPhase 3
Flap-sparing radiation for mouth cancer after reconstructive surgery
This trial tests a special radiation technique for people who have had reconstructive surgery for oral cavity cancer. The goal is to see if we can spare the flap (the rebuilt tissue) from high radiation doses to improve healing and quality of life.
AmiensAges 18 years+ - NCT04900558Recruiting
Study outcomes after robotic bladder removal surgery
This trial follows adults who are planning to have a robotic radical cystectomy (surgery to remove the bladder and surrounding tissue) to learn what outcomes to expect. If you choose to join and meet the basics, it may help your team compare results and improve care for future patients.
Florence, TuscanyAges 18 years+ - NCT05363189Recruiting
Improving recovery after breast reconstruction with belly-tissue flap
This study looks at ways to help your recovery after breast reconstruction using tissue moved from your lower belly (a DIEP flap). You may be asked to complete a questionnaire during the recovery period.
GothenburgAges 18–100 - NCT06130332RecruitingPhase 2
Immunotherapy Plus Chemo Before Surgery for Early Oral Cancer
This trial tests a new immunotherapy drug (tirellizumab) combined with chemotherapy before surgery for early-stage oral cancer. It aims to see if this combination can help shrink the tumor and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06236633Recruiting
Blocking an artery before rectal cancer surgery
This trial tests a technique called ischemic preconditioning, where doctors temporarily block a main artery in your gut before rectal cancer surgery to see if it helps reduce complications. If you are scheduled for this type of surgery and meet the health criteria, the study may offer more information about safer recovery.
MontpellierAges 18–90 - NCT06669104Recruiting
Chest surgery using the Medtronic Hugo robot
This study tests whether a robotic system (Medtronic Hugo) can safely help surgeons perform chest surgery with small cuts. If you need chest surgery and are in good health, you may be able to join.
Hong KongAges 18–80 - NCT06720883Recruiting
Robot-assisted surgery for bile duct cancer
This study tests whether robot-assisted surgery is safe and effective for people with perihilar cholangiocarcinoma (a type of bile duct cancer). It may be a good fit for patients whose cancer has not spread and who are healthy enough for major surgery.
PadovaAges 18 years+ - NCT06725576Recruiting
Comparing microwave ablation vs. surgery for low-risk thyroid cancer
This study compares a less invasive procedure (microwave ablation) with traditional surgery for treating a small, low-risk papillary thyroid cancer. If you have a single, small tumor with certain low-risk gene changes, you might be able to avoid surgery and have a quicker recovery.
Guangzhou, GuangdongAges 18–70 - NCT06905015Recruiting
Comparing two methods to reduce blood loss during open liver surgery
This trial tests whether using stroke volume variation (SVV) is better than central venous pressure (CVP) to guide fluid management and reduce bleeding during open liver surgery. It aims to find a safer way to manage fluids during the operation.
Chiang Mai, ChiangmaiAges 20–70 - NCT01558544Recruiting
Freezing ovarian tissue for future fertility after early menopause risk
This study looks at freezing (cryopreserving) ovarian tissue in people who are at risk of early menopause because of cancer treatment or surgery. It may help preserve natural hormone function and possible future fertility for those who cannot or do not want to freeze eggs or embryos.
New York, New YorkAges Up to 45 years - NCT01891318RecruitingPhase 1/Phase 2
Study radiosurgery plus surgery for brain metastases
This trial tests giving focused radiation (radiosurgery) before surgery for certain resectable brain metastases. It may help shrink or control tumors in the brain before they are surgically removed.
Cleveland, OhioAges 18 years+ - NCT04220749RecruitingPhase 2
Radiation vs mouth surgery for HPV-negative throat cancer
This Phase 2 trial compares two standard cancer treatments—radiation or surgery through the mouth—for HPV-negative oropharyngeal throat cancer. It aims to find out which approach works better while keeping side effects and quality of life acceptable.
London, OntarioAges 18 years+ - NCT05378087Recruiting
Compare two ways to plan treatment for cervical cancer
This study compares two staging methods—using surgery results versus imaging tests—to help doctors plan treatment for locally advanced cervical cancer. It may improve how accurately the cancer is mapped, which could affect treatment choices and outcomes.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT03545256Recruiting
Outpatient surgery to map lymph nodes in mouth and throat cancer
This trial studies a planned, same-day (outpatient) surgery approach to find and check cancer spread to nearby lymph nodes in early-stage mouth and throat squamous cell cancer. It may help doctors remove the right lymph nodes and decide on any needed further treatment.
Montpellier, HéraultAges 18 years+ - NCT06783491RecruitingPhase 3
Chemotherapy with or without heated chemo for advanced colon cancer
This trial tests if adding heated chemotherapy directly into the abdomen during surgery improves outcomes for people with advanced colon cancer that hasn't spread to other organs. It compares standard chemotherapy before surgery alone versus chemotherapy before surgery plus heated chemo during surgery.
Córdoba, CórdobaAges 18–75
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Common questions
- Are there clinical trials for cancer surgery?
- Yes. Clin2 currently lists 860 recruiting cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.