Clinical trials
Cardiac Surgery With Cardiopulmonary Bypass clinical trials
Below are recruiting cardiac surgery with cardiopulmonary bypass clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06984276Recruiting
Nerve blocks for pain relief in children having heart surgery
This study compares two different ultrasound-guided numbing injections (pectoral nerve block vs. transverse thoracic plane block) to see which provides better pain control for children aged 6 months to 7 years undergoing heart surgery through a chest incision with a heart-lung machine.
CairoAges 6 months–7 years - NCT07013591RecruitingPhase 2
Nicotinamide mononucleotide for heart surgery recovery
This study tests whether taking nicotinamide mononucleotide (a dietary supplement) before and after heart surgery can help reduce complications and improve recovery. It is for people having heart bypass or valve surgery who are at higher risk of problems after surgery.
Boston, MassachusettsAges 18 years+ - NCT06705855Recruiting
Predicting kidney injury after heart surgery using skin sensors
This study tests whether a special light-based monitor on your skin (near your kidney and arm) can predict kidney injury after heart surgery. It aims to help doctors protect your kidneys during and after the procedure.
Salt Lake City, UtahAges 18 years+ - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT06279793RecruitingPhase 2
Fish oil for recovery after high-risk heart surgery
This trial tests if giving fish oil through a vein before and after heart surgery can help patients recover faster. It is for people who have a high risk of complications during surgery.
AugsburgAges 18 years+ - NCT06096116RecruitingPhase 3
Trial of a blood product for heparin resistance during heart surgery
This study tests a blood-derived medicine (antithrombin) to help people who do not respond well to the blood thinner heparin during heart surgery. It aims to make surgery safer by improving blood thinning.
Stanford, CaliforniaAges 18–85 - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT07032792RecruitingPhase 2
FEIBA versus plasma for bleeding after heart surgery
This trial compares two treatments for bleeding after heart surgery: a medicine called FEIBA (which helps blood clot) and fresh frozen plasma (a blood product). The goal is to see which works better as a first treatment for bleeding during recovery.
Manhasset, New YorkAges 18 years+ - NCT07037043RecruitingPhase 3
Steroid medicines for high-risk heart surgery patients
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
AmiensAges 18 years+ - NCT04754022Recruiting
Blood use during heart surgery in younger adults
This study looks at how much donated blood (blood products) is needed for younger adults during heart surgery that uses a heart-lung machine. It may help doctors choose safer, more appropriate blood-saving plans for people like you.
Portland, MaineAges 18–65 - NCT05879432RecruitingPhase 2
Peptide treatment to prevent or lessen kidney injury after heart surgery
This Phase 2 trial tests an LSALT peptide given around the time of “on-pump” heart surgery to help prevent or reduce acute kidney injury (a sudden drop in kidney function). It may help people who are at higher risk for kidney injury during or after surgery.
Calgary, AlbertaAges 18 years+ - NCT03204357Recruiting
Using your own blood after heart-lung machine surgery
This trial studies giving a “fresh” blood transfusion from your own blood after heart surgery that uses a heart-lung machine. It may help patients avoid needing donated blood, but it only works for people who meet specific safety and timing requirements.
Aurora, ColoradoAges 18–90 - NCT06710353Recruiting
Albumin before heart surgery for kids with low albumin
This study tests whether giving albumin (a protein in the blood) before heart surgery helps protect the kidneys of young children with low albumin levels. It may help reduce the risk of kidney injury after surgery.
Seoul, SeoulAges Up to 7 years - NCT07024420Recruiting
Sigh breathing during heart surgery with heart-lung machine
This study tests if adding occasional deep breaths (sighs) during heart surgery helps patients recover better after using the heart-lung machine. It is for people having planned (not emergency) heart surgery.
Nanjing, JiangsuAges 18 years+ - NCT07314138Recruiting
Comparing two minimally invasive heart bypass surgeries for three-vessel disease
This trial compares two types of heart bypass surgery for people with blockages in three main heart arteries. It tests a hybrid approach that combines a small incision bypass with a stent, versus a standard off-pump bypass. This may mean less recovery time for some patients.
Leuven, Vlaams BrabantAges 18–85 - NCT07144267Recruiting
Comparing two heart medications during surgery
This trial compares two medicines, milrinone and epinephrine, given during heart surgery to see which one better helps the right side of the heart work. It may help patients with weaker right heart function.
Al MansurahAges 18–70 - NCT06487585RecruitingPhase 4
Angiotensin II as first pressor after heart surgery
This trial tests if starting Angiotensin II early, instead of other blood pressure medications, can help heart surgery patients maintain safe blood pressure. It may be an option if you have low blood pressure after surgery despite receiving fluids.
Towson, MarylandAges 18 years+ - NCT05740397Recruiting
Testing blood pressure targets during heart-lung bypass
This trial compares different strategies for keeping a specific blood pressure level during heart-lung bypass surgery. It may help reduce complications by finding the safest blood pressure target during the operation.
VeronaAges 18–80 - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT06355063Recruiting
CellFX device for atrial fibrillation during open-heart surgery
This trial tests a new device called CellFX that uses nanosecond pulsed field ablation to treat atrial fibrillation during open-heart surgery. It may help you if you already need heart surgery and also have AFib.
ViennaAges 18–85 - NCT07267546Recruiting
Study on heart-lung machine fluid and its effects in heart surgery
This study looks at how the fluid used to fill the heart-lung machine affects the body's chemistry and recovery in patients having heart surgery. It may help doctors choose the best fluid for better outcomes after bypass surgery.
LundAges 18 years+ - NCT06615102RecruitingPhase 3
Testing if angiotensin II prevents kidney injury after heart surgery
This trial tests whether giving a medicine called angiotensin II during heart surgery can help prevent acute kidney injury (a sudden drop in kidney function). It is for adults having certain types of heart surgery who have a higher risk of kidney problems.
BerlinAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for cardiac surgery with cardiopulmonary bypass?
- Yes. Clin2 currently lists 81 recruiting cardiac surgery with cardiopulmonary bypass studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery with cardiopulmonary bypass trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery with cardiopulmonary bypass trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.