Clinical trials
Cardiac Surgery With Cardiopulmonary Bypass clinical trials
Below are recruiting cardiac surgery with cardiopulmonary bypass clinical trials, each written for real people, not researchers. We’re tracking 80 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06917859RecruitingPhase 1
Steroid to protect kidneys during heart surgery
This trial is testing whether a single dose of the steroid methylprednisolone, given before heart surgery, can protect your kidneys from damage during the operation. If you qualify, you'll receive the drug or a placebo, and your kidney function will be monitored closely.
Cairo, AbbasiaAges 18–65 - NCT07077772Recruiting
Guiding fluid removal after heart surgery
This trial tests a method to guide how much fluid is removed after heart surgery using a urine salt test, to see if it helps patients recover better. If you are having planned heart surgery with a heart-lung machine, you may be able to join.
AmiensAges 18 years+ - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT07632131Recruiting
Storytelling therapy to prevent PTSD after heart surgery
This study tests whether a special therapy called narrative exposure—where you talk through your surgery experience with a trained counselor—can help prevent PTSD (post-traumatic stress) in people recovering from heart surgery in the ICU. The goal is to help you process what happened so you feel less distressed afterward.
Fuzhou, FujianAges 18 years+ - NCT07549243Enrolling by invitation
Ear Nerve Stimulation to Protect Kidneys During Heart Surgery
This trial tests whether gentle electrical stimulation applied to your ear can help protect your kidneys during heart surgery that uses a heart-lung machine. Kidney damage after this type of surgery is common, and researchers want to see if this non-invasive stimulation can prevent it.
Hangzhou, ZhejiangAges 18 years+ - NCT06516432Recruiting
Nerve block and lactate in heart surgery
This study looks at how a nerve block near the breastbone (parasternal block) affects lactate levels in the blood for patients having heart surgery. It aims to understand if this pain management technique can help keep lactate levels normal during recovery.
Guadalajara, JaliscoAges 18 years+ - NCT07032792RecruitingPhase 2
FEIBA versus plasma for bleeding after heart surgery
This trial compares two treatments for bleeding after heart surgery: a medicine called FEIBA (which helps blood clot) and fresh frozen plasma (a blood product). The goal is to see which works better as a first treatment for bleeding during recovery.
Manhasset, New YorkAges 18 years+ - NCT07418242Recruiting
New markers for kidney risk after heart surgery
This study looks at whether certain blood or urine markers can predict kidney problems in people having high-risk heart surgery. The goal is to find early warning signs so doctors can take steps to protect your kidneys.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07037043RecruitingPhase 3
Steroid medicines for high-risk heart surgery patients
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
AmiensAges 18 years+ - NCT04754022Recruiting
Blood use during heart surgery in younger adults
This study looks at how much donated blood (blood products) is needed for younger adults during heart surgery that uses a heart-lung machine. It may help doctors choose safer, more appropriate blood-saving plans for people like you.
Portland, MaineAges 18–65 - NCT05879432RecruitingPhase 2
Peptide treatment to prevent or lessen kidney injury after heart surgery
This Phase 2 trial tests an LSALT peptide given around the time of “on-pump” heart surgery to help prevent or reduce acute kidney injury (a sudden drop in kidney function). It may help people who are at higher risk for kidney injury during or after surgery.
Calgary, AlbertaAges 18 years+ - NCT03204357Recruiting
Using your own blood after heart-lung machine surgery
This trial studies giving a “fresh” blood transfusion from your own blood after heart surgery that uses a heart-lung machine. It may help patients avoid needing donated blood, but it only works for people who meet specific safety and timing requirements.
Aurora, ColoradoAges 18–90 - NCT07024420Recruiting
Sigh breathing during heart surgery with heart-lung machine
This study tests if adding occasional deep breaths (sighs) during heart surgery helps patients recover better after using the heart-lung machine. It is for people having planned (not emergency) heart surgery.
Nanjing, JiangsuAges 18 years+ - NCT06710353Recruiting
Albumin before heart surgery for kids with low albumin
This study tests whether giving albumin (a protein in the blood) before heart surgery helps protect the kidneys of young children with low albumin levels. It may help reduce the risk of kidney injury after surgery.
Seoul, SeoulAges Up to 7 years - NCT06487585RecruitingPhase 4
Angiotensin II as first pressor after heart surgery
This trial tests if starting Angiotensin II early, instead of other blood pressure medications, can help heart surgery patients maintain safe blood pressure. It may be an option if you have low blood pressure after surgery despite receiving fluids.
Towson, MarylandAges 18 years+ - NCT05740397Recruiting
Testing blood pressure targets during heart-lung bypass
This trial compares different strategies for keeping a specific blood pressure level during heart-lung bypass surgery. It may help reduce complications by finding the safest blood pressure target during the operation.
VeronaAges 18–80 - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT06355063Recruiting
CellFX device for atrial fibrillation during open-heart surgery
This trial tests a new device called CellFX that uses nanosecond pulsed field ablation to treat atrial fibrillation during open-heart surgery. It may help you if you already need heart surgery and also have AFib.
ViennaAges 18–85 - NCT07267546Recruiting
Study on heart-lung machine fluid and its effects in heart surgery
This study looks at how the fluid used to fill the heart-lung machine affects the body's chemistry and recovery in patients having heart surgery. It may help doctors choose the best fluid for better outcomes after bypass surgery.
LundAges 18 years+ - NCT05927233RecruitingPhase 4
Methylprednisolone in children after open-heart surgery
This trial tests whether giving methylprednisolone (a steroid medicine) can lower the body’s inflammatory response in children during the first day after congenital open-heart surgery. It may help reduce harmful inflammation and improve recovery for some children undergoing their first surgery.
Karachi, SindhAges 1 month–18 years - NCT06615102RecruitingPhase 3
Testing if angiotensin II prevents kidney injury after heart surgery
This trial tests whether giving a medicine called angiotensin II during heart surgery can help prevent acute kidney injury (a sudden drop in kidney function). It is for adults having certain types of heart surgery who have a higher risk of kidney problems.
BerlinAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT06013189Recruiting
Adjusting gas flow during heart-lung machine rewarming
This study tests how adjusting the amount of sweep gas (a gas mixture) during the rewarming phase of heart-lung machine use might affect patients. It's for people having planned heart surgery with a standard heart-lung machine, not minimally invasive or robotic surgery.
Istanbul, AltunizadeAges 18 years+ - NCT06959121Recruiting
Treating AFib during open-heart surgery with a new device
This trial tests a new device used during open-heart surgery to treat atrial fibrillation (AFib) by delivering tiny, fast electrical pulses to the heart tissue. It is for people who are already having heart surgery and want to also treat their AFib at the same time.
St. Helena, CaliforniaAges 18–85
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Common questions
- Are there clinical trials for cardiac surgery with cardiopulmonary bypass?
- Yes. Clin2 currently lists 80 recruiting cardiac surgery with cardiopulmonary bypass studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery with cardiopulmonary bypass trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery with cardiopulmonary bypass trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.