Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05028686Recruiting
Using blood tests and AI to predict heart failure readmissions
This study looks at hospital and emergency patients with heart failure and uses “omics” (advanced lab data from the body) plus statistics and artificial intelligence to predict who is likely to return to the hospital soon. If it works, it could help doctors better plan follow-up care to reduce repeat hospital visits.
Toronto, OntarioAges 18–105 - NCT05230745Recruiting
Test device for heart failure safety and how well it works
This trial studies whether the ContraBand device can be safely placed in people with long-term, symptomatic heart failure and reduced heart pumping. It also looks at whether the approach is practical and tolerable, and gathers early safety information.
AalstAges 18–85 - NCT05485376Recruiting
Pulmonary artery catheter use in cardiogenic shock patients
This trial studies whether using a special pressure-monitoring tube in the heart’s main artery (a pulmonary artery catheter) helps people who are in cardiogenic shock from weak heart pumping. If you qualify, the goal is to improve how doctors monitor and treat this dangerous, fast-moving condition.
Boston, MassachusettsAges 18–90 - NCT05564793Recruiting
Noninvasive heart mapping to improve CRT outcomes
This trial tests whether a special noninvasive heart “mapping” test done on the body can help improve outcomes for people who need a CRT device. It studies whether mapping before implantation can better guide or predict how well the CRT will work.
AmsterdamAges 18–85 - NCT05712824Recruiting
Device to measure left-heart pressure in advanced heart failure
This trial tests a wirelessly implanted device that measures pressure in the left upper heart chamber (left atrial pressure) in people with advanced heart failure. By tracking that pressure, researchers hope to better understand disease status and guide care.
Tbilisi, GeorgiaAges 22–88 - NCT05723679Recruiting
Breathing-targeted program to improve function in HFpEF
This trial studies a breathing-focused treatment to help people with HFpEF (a type of heart failure) feel and function better. It may help improve daily activity by addressing breathing limits that commonly come with this condition.
Dallas, TexasAges 55–90 - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT05876000Recruiting
Heart pump study for very severe heart failure
This trial tests a left ventricular assist system (a mechanical heart pump for the left side of the heart) in people with very severe heart failure. It may help people who are too sick or not improving despite best available medical treatment.
GrazAges 18–75 - NCT06130059RecruitingPhase 2
Low-dose colchicine for heart failure with inflammation
This trial tests whether a low-dose colchicine (LoDoCo) can help people with heart failure and inflammation feel better and exercise more. It is for adults 50 and older with HFpEF who have signs of inflammation in their blood.
Dallas, TexasAges 50 years+ - NCT06147336Recruiting
Testing the V-Lap system for heart failure monitoring
This trial tests a new device called V-Lap that is placed in the heart to monitor pressure. It may help doctors better manage heart failure and reduce hospital stays. Researchers want to see if it works well in people with mild to moderate heart failure.
Boston, MassachusettsAges 22–88 - NCT06158698RecruitingPhase 3
Colchicine for heart inflammation with arrhythmias
This trial tests whether the drug colchicine can help people with heart muscle inflammation (myocarditis) that also causes abnormal heart rhythms, a weak heart pump, or high stress markers. Colchicine is an anti-inflammatory medicine that might reduce heart damage and improve symptoms.
Naples, CampaniaAges 18 years+ - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT06356727Recruiting
Blood vessel health test for heart recovery
This study checks if tiny blood vessel problems in the heart affect how well the heart muscle recovers after being weak. It uses special imaging during a routine heart catheterization to look at these small vessels.
FerraraAges 18–85 - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06543173Recruiting
Preventive heart ablation with defibrillator in high-risk patients
This study tests if doing a special heart procedure (catheter ablation) at the same time as implanting a defibrillator (ICD) can prevent dangerous heart rhythms better than the ICD alone. It is for people with a very weak heart pump due to blocked arteries who are getting a first-time ICD.
Copenhagen, Region HAges 18 years+ - NCT06561932Recruiting
Leadless pacemaker for heart failure resynchronization
This trial tests a completely leadless pacemaker (WiSE® CRT) for heart failure patients who need cardiac resynchronization therapy (CRT). It aims to avoid the long-term risks of traditional wires (leads) in the heart.
Birtinya, QueenslandAges 22 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06648733Recruiting
Better medication safety when leaving the hospital for palliative care
This trial studies how to improve medication management when patients with advanced illnesses move from hospital care to home care in Muenster. It aims to make the switch smoother and safer for people who need palliative (comfort-focused) treatment.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT05330221Recruiting
Healthy heart check-in for people at risk of heart failure
This study focuses on adults in the Detroit area who have high blood pressure and other risk factors for heart failure, but have not been diagnosed with heart failure yet. It aims to test an approach to help identify and reduce risk early.
Detroit, MichiganAges 18 years+ - NCT06741436Recruiting
Exercise testing after preeclampsia
This study looks at how the heart and blood vessels work after a pregnancy complicated by preeclampsia. It uses exercise testing to see if there are lasting effects, which may help improve long-term heart health monitoring and care.
Nashville, TennesseeAges 18 years+ - NCT06747429Recruiting
High-fat diet for heart failure metabolism
This trial tests whether a high-fat diet can help change how your heart uses energy, potentially improving heart function in people with non-ischemic heart failure.
ParisAges 18 years+ - NCT06849752Recruiting
Early heart failure screening for high-risk patients
This trial checks for early signs of heart failure in people who have multiple risk factors. It will use blood tests, a wearable device, and a handheld ultrasound to find any changes early, so treatment can start quickly.
Cleveland, OhioAges 40 years+ - NCT06956560Recruiting
Heart Scar Imaging Study for Heart Attack and Failure Patients
This study uses a special imaging agent to see a protein called PDGFRß in the heart, which may help detect scarring (fibrosis) after a heart attack or in heart failure. It aims to improve how we understand and treat heart muscle damage.
UppsalaAges 40–70 - NCT07022067Recruiting
Smartphone study for chronic coronary syndrome
This study tests if a smartphone app can help people with a chronic heart condition called coronary syndrome. It aims to make care easier and track symptoms at home.
Milan, ItalyAges 18 years+
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 396 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.