Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06578078RecruitingPhase 3
Best heart failure care for older patients with kidney disease
This study tests the best way to manage heart failure in older adults who also have kidney problems and high potassium levels. It compares different treatment strategies to see which one is safest and most effective.
Alcorcón, MadridAges 70 years+ - NCT06578520RecruitingPhase 4
Testing dapagliflozin for heart failure on dialysis
This trial tests whether adding dapagliflozin (a medication that helps protect the heart and kidneys) helps people with heart failure who are also on peritoneal dialysis. It may offer extra support for your heart and kidney health.
ValenciaAges 18 years+ - NCT06593223Recruiting
Noninvasive heart sound test for heart failure congestion
This trial tests a new, noninvasive device that uses low-frequency heart sounds to check for fluid buildup (congestion) in people with heart failure. It may help doctors monitor your condition without needles or surgery.
Shenzhen, GuangdongAges 18 years+ - NCT06601465RecruitingPhase 2
Vericiguat for cognitive health in heart failure
This study tests whether the heart failure medication vericiguat can also improve thinking and memory in people with heart failure who have mild cognitive problems. It involves taking vericiguat pills and having brain scans to track changes.
Calgary, AlbertaAges 18 years+ - NCT06626685Recruiting
Clonal blood cells in heart failure
This study looks at whether changes in blood cells (called clonal hematopoiesis) are linked to heart failure. By testing your blood, researchers hope to learn more about how heart failure progresses and find new ways to treat it.
BergamoAges 18 years+ - NCT06675448Recruiting
Best practices for heart failure with leaky mitral valve
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
Falls Church, VirginiaAges 18–99 - NCT06676696RecruitingPhase 4
Stopping immunosuppression after failed kidney transplant
This study compares what happens when patients with a failed kidney transplant (still in the body) stop their immunosuppressant medicines at 6 months versus continuing them. The goal is to safely prevent your immune system from becoming too sensitive, which can make finding a new donor kidney harder.
BarcelonaAges 18 years+ - NCT07687186RecruitingPhase 3
Qishen Yiqi pills for chronic heart failure
This trial tests whether Qishen Yiqi Dripping Pills, a Chinese herbal medicine, can help people with chronic heart failure caused by coronary heart disease. It is for adults who have been on stable heart failure treatment for at least two weeks.
Bozhou, AnhuiAges 18–80 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Houma, LouisianaAges 18–85 - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT06758128Recruiting
Genes and immunity in worsening heart failure
This study looks at how your genes and immune system affect heart failure. Researchers want to understand why some people have flare-ups (exacerbations) and how the body responds.
San Giovanni Rotondo, FoggiaAges 18 years+ - NCT06783335Recruiting
Cordella sensor for chronic heart failure
This trial studies a small sensor placed in the lung artery to help manage chronic heart failure. It compares patients who get the sensor to those who receive standard care, to see if the sensor improves outcomes.
Naperville, IllinoisAges 18 years+ - NCT06785506Recruiting
Personalized heart failure treatment using multiple biomarkers
This trial tests if using a combination of biomarkers can help personalize treatment for people with a specific type of heart failure called HFpEF (or heart failure with preserved ejection fraction). It aims to find better treatments based on your individual test results.
Alkmaar, North HollandAges 18 years+ - NCT06851949RecruitingPhase 2
Vsling device for ventricular repair in heart failure
This trial tests a new device called Vsling, which is placed inside the heart to help reshape the main pumping chamber (left ventricle) in people with heart failure. It may improve your heart's strength and reduce symptoms like shortness of breath.
Be’er Ya‘aqovAges 18 years+ - NCT06909682Recruiting
AI monitoring with wearables for chronic heart failure
This trial tests an AI system that uses wearable devices and mini-invasive tools to monitor people with chronic heart failure. The goal is to detect changes early and help manage the condition at home.
SalernoAges 19 years+ - NCT06929806RecruitingPhase 3
Iron infusion for iron deficiency with heart failure
This study tests whether giving iron through a vein can help people with heart failure and low iron levels feel better. It compares iron treatment to no iron treatment.
Pasadena, CaliforniaAges 18 years+ - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT06961929Recruiting
Heat and Heart Failure Study
This study looks at how heat affects the body in people with stable heart failure compared to healthy volunteers. It may help researchers understand how to better manage heart failure in daily life.
Dallas, TexasAges 45 years+ - NCT06979726RecruitingPhase 4
Lasix under the skin for heart failure symptoms
This study tests a way to give a common water pill (called Lasix, or furosemide) under the skin using a small pump at home, instead of in the hospital. It may help people with heart failure who have fluid buildup that isn't getting better with oral water pills.
Gainesville, FloridaAges 18–80 - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07023536Recruiting
Heart rehab program from home for chronic heart failure
This trial tests a cardiac telerehabilitation program for people with chronic heart failure. It is designed to see if doing rehab at home using digital tools helps improve health and quality of life.
SalernoAges 18 years+ - NCT07047547Recruiting
Vericiguat study for kidney disease and heart failure patients
This trial tests how a medication called vericiguat works in people with both chronic kidney disease and heart failure. It aims to see if the drug helps manage these conditions together.
Guangzhou, GuangdongAges 18–80 - NCT07149714Recruiting
Heart pump support for high-risk angioplasty
This trial tests the iVAC 2L device, a temporary heart pump placed in the main artery, to help patients who need a high-risk angioplasty (PCI) because of a very narrowed or blocked coronary artery. The goal is to prevent the heart from failing during the procedure.
MoscowAges 18 years+ - NCT07185100Recruiting
Finding early heart failure in at-risk adults across Germany
This study uses heart MRI scans to find unrecognized heart failure in people who have risk factors like diabetes, kidney disease, high blood pressure, or obesity but haven't been diagnosed with heart failure yet. If you join, you will help researchers learn how common hidden heart failure is and take an important step for your own heart health.
BerlinAges 40–69
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 396 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.