Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06805253Recruiting
Heart recovery after surgery for leaky aortic valve
This trial studies how well the heart's main pumping chamber (left ventricle) recovers after surgery to fix a leaky aortic valve. It is for people who also have a leaky mitral valve and an enlarged left ventricle, and who are having their first planned valve surgery.
MoscowAges 18 years+ - NCT06940544Recruiting
Heart failure screening study for adults 40+
This study is looking for people who may have undiagnosed heart failure. It tests a self-screening method at home to find heart problems earlier.
UppsalaAges 40 years+ - NCT07201714RecruitingEarly Phase 1
Carnitine supplement for heart failure with kidney issues
This trial tests whether taking carnitine supplements by mouth can help people who have both heart failure and early-to-moderate kidney problems. It's an early-phase study to see if the supplement is safe and works for this group.
London, OntarioAges 18 years+ - NCT07402239Recruiting
Heart failure therapy and monitoring device study
This trial tests a device that treats and monitors heart failure. It may help people with chronic heart failure and reduced heart function who still have symptoms despite standard treatments.
Fuzhou, FujianAges 18 years+ - NCT07552142Recruiting
Heart Failure Check-In: Using Questionnaires to Spot Early Warning Signs
This study asks heart failure patients who recently were hospitalized to answer regular questionnaires about how they're feeling. Researchers want to see if these questions can detect when heart failure is getting worse before a patient needs emergency care.
Moscow, Non-US/Non-CanadianAges 18 years+ - NCT07485816Enrolling by invitation
Heart-brain oxygen and thinking changes in heart failure
This study looks at how well your heart and brain work together to use oxygen, and how that relates to changes in thinking and memory for people with heart failure.
Kunming, YunnanAges 18–70 - NCT07166965Enrolling by invitation
Supplement for Heart Failure: Ketones and Hawthorn
This trial tests whether adding a supplement containing ketones and hawthorn extract can help people with heart failure feel better and improve their heart function. You will take the supplement daily and have imaging scans and exercise tests to monitor your progress.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Stanford, CaliforniaAges 18–75 - NCT07180368Recruiting
Managing multiple medications in older adults
This study looks at how to better manage multiple medications in older adults with long-term health conditions. It aims to improve safety and reduce drug-related problems.
Xi'an, ShaanxiAges 65 years+ - NCT07667452Recruiting
AI patch study for heart failure recognition
This trial tests a new AI computer model that uses a single feature from a wearable patch to help recognize heart failure more easily. If you have heart failure with moderate to severe symptoms, this study may help improve how we monitor your condition.
Hangzhou, ZhejiangAges 18 years+ - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT02898181Recruiting
Ear cartilage stimulation for sudden heart failure worsening
This trial tests whether a gentle stimulation near your ear (on the tragus, a small ear area) can help people whose heart failure has recently gotten worse while in the hospital. If it works, it may improve symptoms and recovery during this acute phase.
Oklahoma City, OklahomaAges 18–80 - NCT05323487RecruitingPhase 1
Study why water pills (diuretics) stop working in heart failure
This Phase 1 study looks at why “water pills” sometimes stop relieving fluid overload in people with heart failure. It may help researchers understand the causes of diuretic resistance and improve future treatment for fluid management.
New Haven, ConnecticutAges 18 years+ - NCT05753059RecruitingPhase 1
Study why some water pills stop working in heart failure
This Phase 1 study looks at why “water pills” (diuretics) like bumetanide may not remove fluid as expected in people with heart failure. The results may help clinicians improve treatment strategies for fluid control in the future.
New Haven, ConnecticutAges 18 years+ - NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06209359RecruitingPhase 1
Testing a second diuretic for heart failure patients
This trial tests whether adding a second type of diuretic (water pill) can help people with heart failure who don't respond well to their current diuretic. It aims to find better ways to manage fluid buildup.
New Haven, ConnecticutAges 18 years+ - NCT06495892RecruitingPhase 4
PVP-guided fluid removal for heart failure patients
This study tests a new way to guide fluid removal (decongestive therapy) in people hospitalized for heart failure. It aims to help doctors safely reduce fluid buildup, no matter what type of heart failure you have.
AnkaraAges 18–99 - NCT07009132Recruiting
Liver function test for adults with Fontan or heart failure
This study tests a simple liver function test (called dual cholate clearance) to see how well it works in adults with a Fontan circulation or right heart failure. It aims to help doctors better detect liver problems in these heart conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07296081Recruiting
PET scan study for heart scarring in heart failure
This study uses a special PET scan to look for scarring (fibrosis) in the heart muscle of people with heart failure. It may help doctors better understand why some hearts get stiff or weak.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07375433Recruiting
Heart failure and COPD study for patients aged 50 to 70
This trial looks at how heart failure with preserved pumping function affects people who also have COPD. It aims to understand the course of the disease and long-term outlook.
Kazan'Ages 50–70 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT06992089Recruiting
Pacemaker study for heart failure with low heart rate
This trial tests a special pacemaker setting to help your heart beat faster during exercise. It may improve your ability to be active if you have heart failure with preserved ejection fraction (HFpEF) and a low resting heart rate.
ValenciaAges 18 years+ - NCT07499661Recruiting
Study of blood clots in the lungs with heart failure
This study looks at whether a blood clot in the lungs (pulmonary embolism) is a hidden cause in patients who are hospitalized for acute heart failure. It involves additional imaging tests to find a clot if present, which could change your treatment.
AgenAges 18 years+ - NCT05955456Recruiting
Check ways to spot early heart failure
This study looks for people who may be developing heart failure early, using heart imaging and related checks. If you fit the risk pattern, the results may help find heart failure sooner in similar people.
Manchester, Greater ManchesterAges 50 years+
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 396 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.