Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 297 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07004634Recruiting
Comparing Drain Types After Minimally Invasive Esophageal Cancer Surgery
This study compares two different ways of placing drains after minimally invasive surgery for esophageal cancer. It aims to find which method helps you recover better and with fewer complications.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07060495RecruitingPhase 3
RADA16 gel for pain after adult tonsillectomy
This trial tests a new gel (RADA16) placed on the tonsil area after surgery to see if it helps reduce pain and speed healing. It is for adults having a standard tonsillectomy.
Livingston, New JerseyAges 18 years+ - NCT07090928RecruitingPhase 4
Numbing medicine for less pain after knee scope surgery
This study tests whether giving bupivacaine (a numbing medicine) around the time of knee arthroscopy can reduce pain at the surgery sites and help you move your knee better after the operation.
Peshawar, KPKAges 18–70 - NCT07187310Recruiting
Two types of nerve blocks for gallbladder surgery
This trial compares two different nerve blocks (EXORA and ESP) to see which one works better for pain control during and after laparoscopic gallbladder removal. If you're having elective gallbladder surgery, you may be able to join.
El Fayoum Qesm, Faiyum GovernorateAges 18–65 - NCT07200544RecruitingPhase 4
Meloxicam for skin cancer surgery pain
This study tests if meloxicam, an anti-inflammatory painkiller, helps control pain after Mohs surgery for skin cancer. It aims to reduce the need for stronger opioid pain medicines.
Oklahoma City, OklahomaAges 18–110 - NCT07221617RecruitingPhase 4
Methadone for pain after heart surgery
This trial tests whether a single dose of methadone given during heart surgery can improve pain control and recovery. It may be an option for people having planned (not emergency) heart surgery.
Rochester, MinnesotaAges 18 years+ - NCT07241949Recruiting
Nerve block for gallbladder surgery pain relief
This study tests a nerve block called the external oblique intercostal block to reduce pain after laparoscopic gallbladder removal. If you are having this surgery, the block may help you need less pain medication and feel more comfortable after the procedure.
AdanaAges 18–65 - NCT07264699Recruiting
Guided nerve block for hernia repair pain control
This trial tests whether a visually guided nerve block (TAP block) during laparoscopic hernia repair reduces pain and improves recovery. If you are having planned hernia surgery, this study may help you experience less pain after the procedure.
Olsztyn, Warmisko-mazurskieAges 18–80 - NCT07310212Recruiting
Comparing two root canal techniques for pain and success
This study compares two methods of filling a root canal after cleaning it: a traditional lateral condensation technique and a newer warm vertical obturation technique. The goal is to see which one causes less pain afterward and has a better success rate.
Amman, Amman GovernateAges 18 years+ - NCT07369726Recruiting
Mobilization and caffeine after cesarean
This trial tests whether getting out of bed and drinking coffee after a planned cesarean can help reduce pain and speed up recovery. It is for women who have moderate to severe pain after surgery.
KonyaAges 18–35 - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89 - NCT07408414Recruiting
Pain relief after laser pilonidal sinus treatment
This trial studies which local numbing method works best to reduce pain after laser treatment for pilonidal sinus. It may help people with this condition feel more comfortable after their procedure.
PožegaAges 18 years+ - NCT07429669Recruiting
Comparing shoulder nerve blocks for pain and breathing
This study compares two different shoulder nerve blocks to see which one provides better pain relief after shoulder surgery while also checking how they affect your breathing. If you are having a shoulder arthroscopy, you may be eligible to help find the safest and most effective pain control option.
Yenimahalle, AnkaraAges 18–65 - NCT07437469Recruiting
Binaural beats for pain and anxiety after surgery
This trial tests if listening to binaural beats (a type of sound therapy) after hip or knee replacement surgery can help reduce pain and anxiety. You would receive the sound therapy through headphones while in the recovery room.
Miami, FloridaAges 18–99 - NCT07439679Recruiting
Anxiety Before Double Jaw Surgery and Your Recovery
This trial studies how anxiety before double jaw surgery affects your body during surgery and your recovery (pain, swelling, and ability to open your mouth). Researchers will use a simple anxiety questionnaire to see if feeling anxious changes your surgical experience.
IstanbulAges 18 years+ - NCT07442435Recruiting
Reiki for recovery after knee replacement surgery
This study tests whether adding Reiki (a gentle hands-on relaxation therapy) to standard care helps people feel better and recover more comfortably after a first-time knee replacement. It may be a good fit if you are having your first knee replacement, are not on certain medications, and haven't tried energy therapies before.
SinopAges 18 years+ - NCT07442721Recruiting
Comparing two types of nerve blocks for hip replacement pain
This study compares two different nerve block methods to see which provides better pain relief for people having a partial hip replacement. It will help doctors choose the best way to manage pain after surgery.
El Fayoum Qesm, Faiyum GovernorateAges 50–90 - NCT05415384Recruiting
Cryotherapy plus surgery for broken ribs
This trial tests whether adding cryotherapy (freezing treatment to the injury area) to standard surgery for broken, displaced ribs can improve recovery. It’s for adults with multiple broken ribs who are getting a surgical stabilization procedure soon after injury.
Winston-Salem, North CarolinaAges 18–80 - NCT07668648Recruiting
Two nerve blocks for shoulder surgery pain relief
This study compares two types of nerve blocks to reduce pain after shoulder surgery. One block is placed near the neck (interscalene) and the other is placed further away (serratus posterior superior intercostal plane block). The goal is to see which works better and has fewer side effects.
Bursa, NilüferAges 18–75 - NCT07510269Recruiting
Nerve blocks for pain control during mastectomy
This study tests two different numbing shots for the chest wall to see which one provides better pain relief during and after mastectomy surgery.
Bursa, NilüferAges 18–75 - NCT07525986RecruitingPhase 4
Pain control after laparoscopic colon surgery using a button-press system
This trial tests a new pain medication (anrikefon) that patients can control themselves by pressing a button after laparoscopic colon surgery. The goal is to see if it works better or safer than standard pain relief, especially for patients whose nerve blocks alone don't fully control pain.
Beijing, Beijing MunicipalityAges 18–75 - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT07561333Recruiting
Pain Relief Methods for Knee Replacement Surgery
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
Çorum, CentreAges 18–80 - NCT07577934Recruiting
Liposomal Bupivacaine for Pain Relief in Gallbladder Surgery
This trial tests a long-acting numbing medication (liposomal bupivacaine) injected around abdominal muscles during laparoscopic gallbladder removal to reduce pain after surgery. The goal is to see if it provides better pain control compared to standard approaches.
Tianjin, Tianjin MunicipalityAges 18–65
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 297 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.