Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT05198791RecruitingPhase 2
Eplerenone for heart injury without blocked heart arteries
This Phase 2 study tests whether eplerenone can improve outcomes after a heart attack (or similar heart injury) when coronary angiography shows no blocked heart arteries. It focuses on people with added cardiovascular risk factors and evaluates how well the treatment works for heart recovery and strain on the heart.
East Kilbride, LanarkshireAges 18 years+ - NCT07094737Recruiting
Heart rehab study for coronary disease or heart failure
This study tracks how well heart rehabilitation works for people with coronary artery disease or heart failure. It aims to improve future care by learning from your experience.
MilanAges 18 years+ - NCT06223633Recruiting
Stent for sudden heart artery tears
This trial tests a special covered stent (a small mesh tube) for treating sudden tears in heart arteries or bypass grafts. If you have a perforation in a vessel of a certain size, this stent may help seal it and stop bleeding.
Dallas, TexasAges Any age - NCT06586749Recruiting
Nurse-led education and phone support to reduce infections after heart bypass
This study tests whether a special nurse-led program of phone calls and education can help reduce infections after heart bypass surgery. You may be eligible if you are at higher risk for infection and have a smartphone.
Heraklion, CreteAges 18 years+ - NCT07390903Recruiting
Heart function test for difficult bypass weaning
This trial studies whether a heart ultrasound test called GLS can help predict complications when patients are taken off the heart-lung machine after heart surgery. It aims to improve management for better outcomes.
RomeAges 18 years+ - NCT05133843Recruiting
Test heart blood-flow measurements before and after TAVI
This study checks whether special heart tests can better understand “in-between” blocked heart arteries before and after TAVI (a valve replacement done through a catheter). It may help doctors choose the safest, most accurate treatment when coronary artery disease is unclear.
LeipzigAges 18 years+ - NCT06424834RecruitingPhase 2/Phase 3
Targeted medicines for chest pain without blocked arteries
This study tests if specific heart medicines (like beta-blockers or calcium channel blockers) can help people with chest pain that is not caused by blocked arteries. It aims to treat the tiny blood vessels or spasms that may be the real cause of your pain.
Palo Alto, CaliforniaAges 18 years+ - NCT05272618Recruiting
Testing heart vessel dysfunction after a heart attack
This trial looks at how to assess small blood-vessel (microvascular) problems in people who had a heart attack but whose main heart arteries are not blocked. It may help doctors better find what’s driving symptoms and choose the right tests and treatments.
Gwangju, GwangjuAges 19 years+ - NCT04889053Recruiting
CT heart scan study in adults with type 2 diabetes
This trial uses a low-dose CT scan of the heart’s arteries to measure coronary artery calcification in people with type 2 diabetes. It aims to better understand heart calcium buildup and may help improve risk assessment for people with diabetes.
HengyangAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06603961Recruiting
Preventing leg swelling after bypass surgery with a special bandage
This trial tests a custom pressure-guided elastic bandage to prevent leg swelling after coronary artery bypass surgery. The bandage is wrapped around the leg where a vein was taken for the bypass.
Bangkok, Bangkok NoiAges 18 years+ - NCT05672706Recruiting
Pressure wave test for people with angina
This study looks at how a pressure waveform in the heart’s blood vessels can be analyzed to learn more about angina (chest discomfort from reduced blood flow). You may be asked to undergo specific heart/blood-flow measurements, which could help improve understanding and future care.
HsinchuAges 21 years+ - NCT04944615Recruiting
IVUS-guided stent placement for blocked heart artery using longer guidance
This trial compares two ways to place a stent (a small mesh tube) for a completely blocked heart artery: using an IVUS camera inside the artery versus using a standard x-ray approach. It may help people get better heart outcomes by improving how accurately the stent is placed in long-term blockages.
BeijingAges 18 years+ - NCT05529459Recruiting
Guidance method for opening heart blockages with stents
This study compares two ways of deciding how completely to open blocked heart arteries using drug-eluting stents. It aims to see which guidance approach improves results and safety for people with coronary artery disease who need a PCI (heart catheter procedure).
AnyangAges 19 years+ - NCT06275399Recruiting
Study of plaque and platelets in narrowed heart arteries
This study looks at how plaque buildup and blood platelets interact in partially blocked heart arteries. It might help find better ways to treat people with chronic coronary syndrome.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07373119Enrolling by invitation
Frailty reduction in stable heart disease patients
This study tests a program to reduce frailty in older adults with stable coronary artery disease. The goal is to improve strength and well-being in people who are not having recent heart problems.
Barcelona, Select...Ages 70 years+ - NCT04599192Enrolling by invitation
Test heart procedure planning in women using pressure measurements
This trial compares two strategies for deciding which heart blockages to treat, using special pressure and blood-flow measurements during a heart procedure. It may help doctors choose more accurate treatment by tailoring the plan to each person’s heart blood flow.
New Haven, ConnecticutAges 18 years+ - NCT05782270RecruitingPhase 4
Blood thinner medicines after bypass surgery with artery unblocking
This trial studies which blood-thinning medicine combination is safest and most helpful after coronary bypass surgery combined with a procedure to unblock the artery (endarterectomy). It focuses on preventing dangerous blood clots while also avoiding excess bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06472908RecruitingPhase 3
Colchicine after stent procedure for heart disease
This trial tests whether colchicine (a medicine used for gout) can help prevent heart problems after a stent procedure (PCI). It's for people who are in the hospital getting a stent and follow standard heart care.
Lanzhou, GansuAges 18–80 - NCT07004569Recruiting
Angiolite Registry Study for heart artery stents
This study is testing a new type of stent for people with a blockage in the main artery of the heart. It aims to see how well the stent works and if it's safe.
Hong Kong, ShatinAges 19 years+ - NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT06539689Recruiting
Sperstent for remaining blockages after balloon treatment in leg arteries
This trial tests a special stent called Sperstent for people who still have blockages or tears in their leg arteries after balloon treatment. It is designed to help improve blood flow and reduce symptoms like leg pain or sores.
Beijing, Beijing MunicipalityAges 18–85 - NCT06179329Recruiting
Comparing two types of heart bypass grafts in women
This trial compares two types of grafts (the radial artery from the arm and a vein from the leg) used in women having heart bypass surgery for the first time. It aims to see which graft works better and stays open longer.
São Paulo, São PauloAges 18–75
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.