Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07457554Recruiting
Can respiratory quotient help ICU patients on ventilators?
This study looks at whether using a simple measurement called the respiratory quotient (a sign of how your body is using fuel) can help doctors make better decisions for patients on a breathing machine in the ICU. It may lead to safer, more personalized care.
Poznan, WielkopolskaAges 18–85 - NCT07448805Recruiting
Accuracy and safety of a glucose monitor in the ICU
This trial tests a continuous glucose monitoring system (Syai Tag) in the intensive care unit (ICU). It aims to see how well it measures blood sugar levels safely compared to standard methods.
MariborAges 18 years+ - NCT07447791Recruiting
Comparing low vs standard dialysis in ICU patients
This trial compares a lower dose versus a standard dose of continuous kidney replacement therapy (CRRT) for critically ill patients with acute kidney injury (AKI — sudden kidney failure). It aims to see if lower doses are safe and effective.
London, Greater LondonAges 18 years+ - NCT07436130Recruiting
Curcumin for adults with sepsis in the ICU
This trial tests if curcumin (a natural compound found in turmeric) can help critically ill patients fighting sepsis, a life-threatening response to infection. It is for adults who are already receiving food through a feeding tube in the ICU.
Guadalajara, JaliscoAges 18 years+ - NCT06814457Recruiting
Nursing care bundle for swallowing after breathing tube removal in children
This trial tests a special nursing care plan to help children who had a breathing tube eat and drink safely after it's removed. It aims to reduce swallowing problems in the intensive care unit.
Kafr ash Shaykh, Kafr Ash Shaykh, Kafr el-Sheikh, Egypt,Ages 6–18 - NCT07417969Recruiting
Albumin with furosemide for fluid overload in ICU
This study tests whether giving a medicine called albumin together with a water pill (furosemide) helps ICU patients who have too much fluid in their body and are making very little urine. The goal is to see if this combination can improve urine output and protect kidney function.
Querétaro City, QuerétaroAges 18–100 - NCT04534296Recruiting
Early mobilization for breathing muscles in critically ill children
This study looks at whether starting movement early in the first day of breathing support can help keep the diaphragm (a key breathing muscle) working better in critically ill children. The researchers will check diaphragm thickness using ultrasound and compare it to usual care.
ShanghaiAges 6 months–12 years - NCT07409727RecruitingPhase 4
Acetylcysteine inhalation to prevent pneumonia in ventilated patients
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
CairoAges 18–64 - NCT07407400RecruitingPhase 4
Sleep medication to prevent confusion in older ICU patients
This study tests whether a sleep medication called lemborexant can help older patients in the ICU sleep better and prevent post-surgery confusion. It may be a good fit if you are over 65 and will be in the ICU for at least two days after surgery.
BangkokAges 65 years+ - NCT07403474RecruitingPhase 4
Using rapid testing to guide antibiotic choice in ventilator pneumonia
This trial tests whether using a rapid test to find the exact bacteria causing your pneumonia can help doctors choose the right antibiotics faster, which might improve your recovery. The study compares this approach to usual care in patients on ventilators.
AlèsAges 18 years+ - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT04905537Recruiting
Genetic screening for newborns after a serious pregnancy loss
This trial looks at doing early genetic testing in newborns/early life cases after a serious pregnancy loss, to learn whether genetics can help understand why it happened. If you have the right timing and sample availability, the results may help future “more precise” care planning and research.
Shanghai, Shanghai MunicipalityAges Up to 3 months - NCT07384585Recruiting
Light therapy study for children in the ICU
This study tests whether light therapy can help children in the pediatric intensive care unit (ICU) feel better and recover. A parent or guardian must be at the bedside and speak English.
Columbus, OhioAges 4–17 - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07372794Recruiting
Lung imaging-guided breathing therapy for patients on ventilators for weeks
This study tests whether using a special lung imaging technique called EIT can help guide breathing exercises and physical therapy for people who have been on a breathing machine for 21 days or more. The goal is to see if this approach helps your lungs work better and speeds up recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+ - NCT07369258Recruiting
Music to prevent confusion in the ICU for older adults
This trial tests whether listening to music can help prevent delirium (sudden confusion) in older patients in the intensive care unit. If it works, it could offer a simple, drug-free way to protect your thinking during a hospital stay.
Buenos Aires, Buenos Aires F.D.Ages 65 years+ - NCT07364162RecruitingPhase 2
Ketone drink for confusion in intensive care patients
This trial tests whether giving a special ketone drink to patients in the ICU can reduce or treat delirium (confusion). If you or a loved one is in the ICU, this treatment might help clear up confusion faster.
Nashville, TennesseeAges 18 years+ - NCT07362862Recruiting
Electrical muscle stimulation to prevent ICU weakness
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Rochester, MinnesotaAges 18–85 - NCT07338240Recruiting
Testing a sickness scoring system in Turkish ICUs
This trial is studying how well a scoring system (SOFA-2) works in Turkish intensive care units (ICUs) to measure how sick patients are. It may help doctors better understand and treat people in ICUs in Türkiye.
Izmir, İzmirAges 18 years+ - NCT07330505Recruiting
Checking blood pressure monitor setup in the ICU
This study looks at how doctors set up the blood pressure monitors in the ICU. It checks if the position of the monitor affects the readings, and it may help improve care for patients on breathing machines and blood pressure support.
GothenburgAges 18 years+ - NCT07329530Recruiting
Muscle and metabolism study in ICU survivors
This study looks at muscle and metabolism changes in people who have been in the ICU for at least 7 days after major abdominal surgery. It aims to understand how recovery affects the body.
LiègeAges 18 years+ - NCT07323472Recruiting
Body positioning and breathing in critically ill patients on ventilators
This study tests whether turning patients on their side affects their breathing and lung health. It aims to improve care for people who need a breathing machine.
Recife, PernamuAges 18 years+
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 336 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.