Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07205952Recruiting
Detecting breathing difficulty in ventilated patients
This study looks at whether a computer system can automatically detect when a patient on a breathing machine (ventilator) is having trouble breathing. It may help doctors respond faster to the patient's needs.
Buenos Aires, Buenos AiresAges Any age - NCT06584604Recruiting
Calibrating esophageal balloon for breathing machine patients
This trial is testing how to calibrate an esophageal balloon (a thin tube that measures pressure in your chest) for people on a breathing machine. If you are already sedated and have this tube in place, participating may help doctors get more accurate readings to improve your breathing support.
Leiden, South HollandAges 18 years+ - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT06547892RecruitingPhase 2
Vasopressin to prevent kidney injury in the ICU
This trial tests if a drug called vasopressin can help prevent acute kidney injury in patients at high risk. It's for adults in the ICU who have a predicted risk score of 5 or higher based on their lab and health data.
São Paulo, São PauloAges 18 years+ - NCT06014801RecruitingPhase 2/Phase 3
Comparing low vs. medium continuous dialysis for kidney injury in the ICU
This study compares two intensities (low vs. medium) of continuous dialysis for people with sudden kidney failure in the ICU. It aims to find which level of treatment works best for critically ill patients.
Sendai, MiyagiAges 18 years+ - NCT06496555Recruiting
Predicting kidney injury in ICU patients
This study tests a tool called U-AKIpredTM to see if it can predict whether a critically ill patient will develop acute kidney injury within the first 12 hours in the ICU. If you are in the ICU and have not had kidney problems before, this trial may help improve your care.
Hangzhou, ZhejiangAges 18 years+ - NCT06487728Enrolling by invitation
Predicting muscle weakness in ICU patients with urine test
This study checks if a urine test and muscle measurements can help predict muscle weakness in critically ill patients. It aims to find an easier way to identify who might get weaker in the ICU.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT07220733RecruitingPhase 1/Phase 2
Exoskeleton rehab after chest surgery in the ICU
This trial tests whether a self-balancing exoskeleton can help people who had chest surgery and are weak (bedbound or nearly so) start walking earlier in the ICU. It aims to see if it is safe and possible to use this device for rehabilitation.
Boston, MassachusettsAges 18 years+ - NCT07048951Recruiting
Memory and awareness after ICU: understanding moments of disconnect
This trial studies episodes of lost or altered consciousness that some people experience after a long stay in the ICU. It aims to understand how these episodes affect memory and recovery.
Liège, LiègeAges 18 years+ - NCT07052123Recruiting
Blood pressure monitoring in ICU with DARE device
This trial tests a new non-invasive device (DARE) to measure blood pressure and core body temperature in patients who are already receiving standard monitoring with an arterial line and a urinary catheter in the ICU.
Saint-Denis, FranceAges 18 years+ - NCT07555041Recruiting
Blood Flow Measurement Comparison in Critically Ill Patients
This study compares two quick methods for checking blood flow and oxygen delivery in very sick patients in the ICU. It helps doctors understand which measurement works better to spot patients who need urgent help.
BronAges 18 years+ - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT07740304Recruiting
Blood flow test to predict survival in sepsis patients
This study checks if a simple blood flow measurement can help predict which patients with sepsis are at higher risk of dying within 28 days. The goal is to see if this test can guide treatment decisions in the ICU.
Edirne, MerkezAges 18 years+ - NCT07737353Recruiting
Education for families of ICU patients with tracheostomy
This study tests whether a structured education program for family members of ICU patients who need a tracheostomy helps them feel more prepared and less stressed. You would be asked to attend training sessions and fill out some questionnaires.
Giresun, GiresunAges 18 years+ - NCT07722897Recruiting
Monitoring brain activity during emergency intubation
This study tests whether monitoring brain activity (using a sensor on the forehead) during emergency intubation helps prevent unstable blood pressure or heart rate. It is for adults who need a breathing tube placed quickly in the emergency room.
AntalyaAges 18 years+ - NCT07718971Enrolling by invitation
Whole-genome sequencing for unexplained medical conditions
This study uses whole-genome sequencing (a complete read of your DNA) to try to find a genetic cause for unexplained medical conditions. If you have a puzzling illness without a clear diagnosis, this test might give you answers.
Seattle, WashingtonAges 18–50 - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT06229990RecruitingPhase 4
Using furosemide stress test to stop kidney replacement therapy
This study tests whether a furosemide (a water pill) stress test can help doctors decide when to safely stop continuous kidney replacement therapy in ICU patients with severe acute kidney injury. It may allow you to come off the machine sooner if your kidneys respond well.
Chiang MaiAges 20 years+ - NCT07707622Enrolling by invitation
Sepsis treatment study for ICU patients
This trial studies treatments for sepsis, a serious infection complication, in ICU patients. It aims to find better ways to care for critically ill patients with sepsis.
BeijingAges 18 years+ - NCT03244293Recruiting
Using a brain monitoring number to grade sepsis severity
This trial tests whether a bedside monitoring number called BIS can help sort sepsis into severity levels. If you have sepsis in the ICU, it may help clinicians track how serious it is and guide care.
Dalian, DalianAges Any age - NCT03451968Recruiting
Amino acid levels in long ICU stays after surgery or trauma
This study measures amino acids (building blocks from food) in people who are critically ill after surgery or trauma while they stay in the ICU for more than a week. It also compares results with healthy adults to better understand how critical illness affects nutrition needs.
Petah TikvaAges 18 years+ - NCT03457831Recruiting
Check a treatment approach for prolonged seizure emergencies
This trial is for adults in the intensive care unit who are having seizures that last at least 5 minutes or keep coming back without fully recovering. It tests a study approach for managing a dangerous seizure emergency and may help doctors improve care for critically ill patients.
AngoulêmeAges 18 years+ - NCT03470467Recruiting
ICU study of a reversible brain swelling condition
This trial looks at Posterior Reversible Encephalopathy Syndrome (PRES) in adults in the ICU. It may help doctors better understand and manage a condition that can cause seizures, confusion, headaches, and vision problems, and that typically shows specific changes on brain scans.
Le ChesnayAges 18 years+ - NCT03753412Recruiting
Rehab program for adults after ICU recovery on ECMO
This trial looks at a recovery and rehabilitation approach for adults who were very sick and needed a machine called ECMO to support breathing and heart function. It may help people regain strength and function after a severe ICU illness.
LondonAges 18 years+
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 352 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.