Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06681649Recruiting
ICU follow-up care for survivors and their caregivers
This study tests a bundle of follow-up care for ICU survivors and their caregivers after leaving the hospital. It aims to improve recovery and support for both patients and their families.
Kingston, OntarioAges 18 years+ - NCT07596043Recruiting
Higher protein for intensive care patients with kidney failure
This study compares giving a higher amount of protein to a standard amount in ICU patients with sudden kidney failure who need dialysis. The goal is to see if more protein helps recovery.
Bangkok, BangkokAges 18 years+ - NCT07599306Recruiting
Telehealth Rehabilitation for Heart Patients After ICU Recovery
This study tests whether supervised remote rehabilitation exercises can help people recover better after a long ICU stay. Many patients struggle with weakness, memory problems, or mood changes after intensive care—this trial aims to improve those symptoms through video-guided therapy.
Milan, MilanoAges 30–75 - NCT07571317Recruiting
Predicting breathing tube removal success in ICU patients
This study tests whether two simple breathing measurements can predict whether patients in the ICU are ready to have their breathing tube removed. If successful, it could help doctors make safer decisions about when patients can breathe on their own.
Istanbul, IstanbulAges 18 years+ - NCT05830669Recruiting
Remote preconditioning therapy for newly sick sepsis patients
This trial studies whether a “remote preconditioning” treatment given during early sepsis can help protect the kidneys and improve outcomes. It is for adults in the ICU very soon after sepsis begins.
MünsterAges 18 years+ - NCT06472999Recruiting
Kidney protection in critically ill ICU patients
This trial tests ways to protect the kidneys in intensive-care patients who have moderate or severe acute kidney injury. If you are on a ventilator or medications to support blood pressure, this study may offer extra kidney care to help prevent further damage.
InnsbruckAges 18 years+ - NCT07562048Recruiting
Comfort Cuddling for Children in Critical Care
This study looks at whether gentle cuddling and physical comfort help children feel better while they're in the intensive care unit. Researchers believe close contact with caregivers may reduce stress and improve how children recover.
Calgary, AlbertaAges Up to 18 years - NCT07551258Recruiting
Immune System Changes and Lung Infection in Critically Ill Older Adults
This study looks at how the immune system changes in older patients on breathing machines in the ICU, and whether these changes affect the risk of developing pneumonia. Understanding this may help doctors better protect critically ill patients from infection.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07542613Recruiting
Educational Program for ICU Patients' Recovery
This study tests whether teaching ICU patients and their families about recovery can help patients regain strength and function after leaving the hospital. Researchers will follow patients for several months after discharge to see if the education makes a difference in their recovery.
Orihuela, AlicanteAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT05671614Recruiting
Prevent muscle stem cell failure after critical illness
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
Prague, Czech RepublicAges 18 years+ - NCT07522580Recruiting
Heart Fluid Response Monitoring in Critically Ill Children
This study tests a simple, non-invasive device that measures how well a child's heart responds when doctors give extra fluids during intensive care. It helps doctors decide if more fluids will actually help the child feel better.
Le Plessis-Robinson, FranceAges birth–8 years - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT07514650Recruiting
Citrate Blood Thinner Safety in Critical Kidney Care
This study tests whether a specific blood-thinning method using citrate works safely and effectively in critically ill patients whose kidneys have suddenly stopped working and need a special filtering machine. Researchers want to confirm that this approach prevents dangerous blood clots while keeping patients safe.
Barcelona, BarcelonaAges 18 years+ - NCT07511582RecruitingPhase 2
Steroids for severe breathing problems in the ICU
This study tests whether a corticosteroid (a type of anti-inflammatory medicine) can help people with severe breathing problems or serious infections who have a specific 'hyperinflammatory' pattern. If you are in the ICU on a ventilator, this trial may be an option for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07499401Recruiting
Fluid response test in ICU patients with vein congestion
This study looks at how tiny blood vessels respond to extra fluids in ICU patients who have vein congestion. It helps doctors understand if giving more fluid is helpful or harmful for you.
Ancona, ItalyAges 18 years+ - NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT07496255Recruiting
Virtual reality for memory help after ICU confusion
This trial tests whether using virtual reality (VR) can help older adults recover their thinking and memory after a serious illness and confusion in the ICU. You may be eligible if you are 50 or older, spent time on a breathing machine, and had delirium in the ICU.
Indianapolis, IndianaAges 50 years+ - NCT06775106Recruiting
Breath test to find lung infections faster
This study tests a new breath analysis method to quickly diagnose respiratory infections in ICU patients on breathing machines. If successful, it could lead to faster treatment for serious lung conditions.
Portland, OregonAges 18–120 - NCT06027684Recruiting
Intensive care decisions, survival, and dying well
This study talks to adults who have been in an intensive care unit (ICU) to understand their views on life-sustaining treatments, end-of-life wishes, and when they would want less or more care. It aims to improve how doctors and families make these hard decisions together.
ManchesterAges 18 years+ - NCT07478380Recruiting
Skin oxygen monitoring in pediatric ICU
This study checks if a skin sensor can accurately measure oxygen levels in the blood of children in the intensive care unit, compared to standard blood tests. It may help reduce the need for frequent needle sticks.
Istanbul, KadıkoyAges 1 month–18 years - NCT07468006Recruiting
Comparing carbon dioxide measurements in critically ill children
This trial tests if a sticker on the skin can accurately measure carbon dioxide levels in the blood, reducing the need for needle sticks in children in the intensive care unit.
BrnoAges 1–18 - NCT07460141Recruiting
Blood tests to predict death risk after surgery in the ICU
This study is looking at whether certain blood tests can help predict the risk of death after surgery in ICU patients. If you have had surgery and are now in the ICU, your blood samples may help doctors learn more.
TrabzonAges 18 years+
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 336 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.