Clinical trials
Critically Ill Patients clinical trials
Below are recruiting critically ill patients clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07596043Recruiting
Higher protein for intensive care patients with kidney failure
This study compares giving a higher amount of protein to a standard amount in ICU patients with sudden kidney failure who need dialysis. The goal is to see if more protein helps recovery.
Bangkok, BangkokAges 18 years+ - NCT07571317Recruiting
Predicting breathing tube removal success in ICU patients
This study tests whether two simple breathing measurements can predict whether patients in the ICU are ready to have their breathing tube removed. If successful, it could help doctors make safer decisions about when patients can breathe on their own.
Istanbul, IstanbulAges 18 years+ - NCT05830669Recruiting
Remote preconditioning therapy for newly sick sepsis patients
This trial studies whether a “remote preconditioning” treatment given during early sepsis can help protect the kidneys and improve outcomes. It is for adults in the ICU very soon after sepsis begins.
MünsterAges 18 years+ - NCT06472999Recruiting
Kidney protection in critically ill ICU patients
This trial tests ways to protect the kidneys in intensive-care patients who have moderate or severe acute kidney injury. If you are on a ventilator or medications to support blood pressure, this study may offer extra kidney care to help prevent further damage.
InnsbruckAges 18 years+ - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT07499401Recruiting
Fluid response test in ICU patients with vein congestion
This study looks at how tiny blood vessels respond to extra fluids in ICU patients who have vein congestion. It helps doctors understand if giving more fluid is helpful or harmful for you.
Ancona, ItalyAges 18 years+ - NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT07447791Recruiting
Comparing low vs standard dialysis in ICU patients
This trial compares a lower dose versus a standard dose of continuous kidney replacement therapy (CRRT) for critically ill patients with acute kidney injury (AKI — sudden kidney failure). It aims to see if lower doses are safe and effective.
London, Greater LondonAges 18 years+ - NCT07436130Recruiting
Curcumin for adults with sepsis in the ICU
This trial tests if curcumin (a natural compound found in turmeric) can help critically ill patients fighting sepsis, a life-threatening response to infection. It is for adults who are already receiving food through a feeding tube in the ICU.
Guadalajara, JaliscoAges 18 years+ - NCT07417969Recruiting
Albumin with furosemide for fluid overload in ICU
This study tests whether giving a medicine called albumin together with a water pill (furosemide) helps ICU patients who have too much fluid in their body and are making very little urine. The goal is to see if this combination can improve urine output and protect kidney function.
Querétaro City, QuerétaroAges 18–100 - NCT07403474RecruitingPhase 4
Using rapid testing to guide antibiotic choice in ventilator pneumonia
This trial tests whether using a rapid test to find the exact bacteria causing your pneumonia can help doctors choose the right antibiotics faster, which might improve your recovery. The study compares this approach to usual care in patients on ventilators.
AlèsAges 18 years+ - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+ - NCT07323472Recruiting
Body positioning and breathing in critically ill patients on ventilators
This study tests whether turning patients on their side affects their breathing and lung health. It aims to improve care for people who need a breathing machine.
Recife, PernamuAges 18 years+ - NCT07307508Recruiting
Scalp block for headache after aneurysm bleeding
This trial tests if a scalp nerve block can better manage severe headaches after a brain aneurysm rupture. It is for patients who had an aneurysm treated with coiling in the intensive care unit.
DohaAges 18 years+ - NCT07306091Enrolling by invitation
Tracheostomy tube removal in critically ill patients
This trial studies the process of removing a tracheostomy tube from critically ill patients who are ready. It focuses on making sure patients can breathe on their own and swallow safely before the tube is taken out.
BursaAges 18 years+ - NCT06683781Recruiting
Breathing machine settings and weaning success study
This study looks at how breathing machine settings and monitoring can help predict if a patient will successfully come off the ventilator. It may help doctors choose better settings for patients who are ready to try breathing on their own.
Buenos AiresAges 18–100 - NCT07254299Recruiting
Hypnosis for ICU recovery and wellbeing
This study tests whether hypnosis sessions during an ICU stay can improve mental and physical recovery after a serious illness. It aims to reduce long-term problems like anxiety, depression, and memory issues.
GenevaAges 18 years+ - NCT07221370RecruitingPhase 2/Phase 3
Vancomycin to prevent C. diff infection in ICU patients
This trial tests whether giving vancomycin through a tube into the stomach can prevent a serious gut infection called C. diff in people who are very sick in the ICU and taking antibiotics. If you qualify, you might receive this medicine to lower your risk.
Moreno Valley, CaliforniaAges 18 years+ - NCT06920173RecruitingPhase 2
Low-dose vasopressors for shock in the ICU
This study tests whether giving low-dose blood pressure medicines through a standard IV (instead of a larger central line) is safe and effective for patients with shock in the intensive care unit.
Kingston, OntarioAges 18 years+ - NCT06928649Recruiting
Studying cell damage in critically ill ICU patients
This trial looks at specific cell damage processes (called ferroptosis and pyroptosis) in very sick ICU patients. The goal is to learn more about these processes so doctors can better treat life-threatening organ failure caused by conditions like sepsis, trauma, or severe bleeding.
EdegemAges 18 years+ - NCT07205952Recruiting
Detecting breathing difficulty in ventilated patients
This study looks at whether a computer system can automatically detect when a patient on a breathing machine (ventilator) is having trouble breathing. It may help doctors respond faster to the patient's needs.
Buenos Aires, Buenos AiresAges Any age - NCT07211620Recruiting
Using procalcitonin blood tests to guide antibiotic decisions in the ICU
This study compares two ways of using a blood test called procalcitonin to decide when to start antibiotics in critically ill patients with a new infection. The goal is to reduce unnecessary antibiotic use while still effectively treating infections.
BudapestAges 18 years+ - NCT07191743Recruiting
Functional Assessment in ICU Patients
This study observes how well adults in the intensive care unit (ICU) can function in daily activities, like moving and caring for themselves. It aims to understand recovery and may help improve care for future ICU patients.
Rio de Janeiro, Rio de JaneiroAges 18 years+
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Common questions
- Are there clinical trials for critically ill patients?
- Yes. Clin2 currently lists 295 recruiting critically ill patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.