Clinical trials
Delirium clinical trials
Below are recruiting delirium clinical trials, each written for real people, not researchers. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06256354Recruiting
Managing body temperature during cancer surgery to prevent confusion
This trial tests whether carefully managing a patient's body temperature during cancer surgery can reduce the risk of postoperative delirium and improve long-term survival. It is for older adults undergoing major cancer surgery.
Chizhou, AnhuiAges 65 years+ - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06107517Recruiting
Reducing delirium after heart bypass with early activity and sleep routines
This trial tests a program that combines gentle early activity and sleep-friendly routines after heart bypass surgery. It aims to reduce the risk of delirium—sudden confusion that can happen after surgery.
SingaporeAges 21–99 - NCT06092671Recruiting
Can FPCA prevent confusion in young kids after surgery?
This study tests whether a medicine called FPCA can prevent sudden confusion (delirium) in young children after surgery. If your child is having short surgery with mask anesthesia for the first time, this study may help them have a smoother recovery.
Wenzhou, ZhejiangAges 2–6 - NCT06052397Recruiting
Sleep and body clock markers for confusion after surgery
This trial tests whether sleep patterns and body clock signals can help predict confusion after major orthopedic surgery. You would wear a watch that tracks movement to see how your sleep relates to recovery.
Boston, MassachusettsAges 70 years+ - NCT05431595RecruitingPhase 2/Phase 3
Test a less sedating plan for agitated delirium in cancer
This study looks at whether using certain sleep/behavior medicines (called neuroleptics) with anti-seizure medicines can calm agitation from delirium without needing as much of the usual “neuroleptic” medicines. It may help people with advanced cancer who are confused and very restless or hard to settle.
Houston, TexasAges 18 years+ - NCT06007755Recruiting
Finding blood markers for confusion after heart surgery
This study is looking for certain substances in the blood that may show up if a person becomes confused or delirious after heart surgery. The goal is to find early warning signs so doctors can help prevent or treat this confusion.
Wuhan, HubeiAges 18 years+ - NCT05837039Recruiting
Comparing caregiver and nurse views of discomfort in advanced cancer
This study compares how healthcare providers and family caregivers judge discomfort in people with advanced cancer who are very hard to rouse and may be actively dying. It aims to understand whether caregiver and staff perceptions match, which could improve comfort care for patients near the end of life.
Houston, TexasAges 18 years+ - NCT05800639Recruiting
Testing brain-wave patterns during pediatric anesthesia awakening
This study looks at brain-wave activity (measured with sensors) in young children during and after general anesthesia for planned eye surgery. It may help doctors understand why some children become very upset or confused as they wake up.
SeoulAges 2–8 - NCT05713877RecruitingPhase 2
Melatonin to treat confusion in ICU patients
This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.
Montreal, QuebecAges 18 years+ - NCT05525702Recruiting
VR sessions to lower confusion in ICU patients
This trial tests whether virtual reality (VR) activities can reduce delirium—new, sudden confusion—in people staying in the ICU. It may help patients feel clearer and more oriented during a longer ICU stay.
Beijing, Beijing MunicipalityAges 18–90 - NCT05541276RecruitingPhase 3
Melatonin to prevent waking confusion in young children after surgery
This study tests whether giving melatonin before surgery can help prevent agitation and confusion in young children after they wake up from anesthesia. Participation may help your child have a smoother recovery after their procedure.
Copenhagen, Capital RegionAges 1–6 - NCT03124303Recruiting
Testing ways to measure and prevent delirium after surgery
This study looks at interventions to help with “postoperative delirium,” a sudden confusion that can happen after surgery, and uses brain measures like EEG and optional MRI. It may help doctors identify who is at risk and learn what approaches are most helpful after surgery.
Madison, WisconsinAges 60 years+ - NCT05127265Recruiting
AI and sensors to monitor patients in the ICU
This study uses AI and sensor data to better monitor people while they are in an intensive care unit (ICU). It may help teams notice changes sooner and improve care for ICU patients.
Gainesville, FloridaAges 18 years+ - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT04876742Recruiting
Wheat beer to help prevent confusion in ICU patients
This study tests whether drinking wheat beer can lower the risk of delirium, a sudden confusion that can happen in intensive care. If you’re at higher risk and can take the study drink safely, this could help you avoid or reduce delirium.
BaselAges 18 years+ - NCT04832568Recruiting
EEG monitoring to predict and prevent postoperative delirium
This study checks brain-wave signals during heart surgery (using EEG monitoring) to understand who is at risk for confusion after surgery. If you qualify, your team will track your thinking after the operation to help reduce or better manage postoperative delirium.
Wuhan, HubeiAges 18 years+ - NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults
This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.
New Delhi, National Capital Territory of DelhiAges 65 years+ - NCT04669457Enrolling by invitationPhase 4
Study of delirium risk in young children having ear surgery
This trial looks at confusion or “delirium” after anesthesia in babies and young children having a myringotomy (ear procedure). It may help doctors understand which children are more likely to experience delirium and how to reduce that risk.
Worcester, MassachusettsAges 3 months–9 years - NCT04355195Recruiting
Preventing delirium after surgery in older patients
This trial tests a “care plan” meant to lower the risk of confusion (delirium) after surgery in people age 70 and older. If you qualify, you may receive additional prevention-focused care before and around your operation.
BerlinAges 70 years+ - NCT04091724Recruiting
EEG monitoring during surgery to reduce delirium in children
This study checks whether using an EEG machine (small sensors that record brain electrical activity) during elective surgery can help prevent or lessen emergence delirium—confusion and agitation right after waking up. It focuses on children under 16 and compares their experience around the time they come out of anesthesia.
Wuhan, HubeiAges Up to 16 years - NCT03774420Recruiting
Study of memory and thinking changes after breast surgery
This trial looks at whether certain anesthesia medications and airway devices are linked to short-term memory or thinking problems after breast surgery. If you’re having breast surgery under general anesthesia, your care team may compare outcomes to learn how to reduce “post-op cognitive dysfunction.”
Treviso, TVAges 18 years+ - NCT04792554Recruiting
Study of aging around major non-heart surgery
This study looks at changes in health and function in older adults before and after major surgery. It may help doctors understand how “aging” affects recovery and what could improve outcomes.
SingaporeAges 65–100 - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+
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Common questions
- Are there clinical trials for delirium?
- Yes. Clin2 currently lists 191 recruiting delirium studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a delirium trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a delirium trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.