Clinical trials · New York
Depression clinical trials in New York
We’re tracking 110 recruiting depression studies with a site in New York — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in New York
- NCT05183230Recruiting
Mobile program to help prevent suicide after hospital stay
This trial tests a phone-based (mobile) support program for middle-aged and older adults after a recent hospital stay for suicidal thoughts or an attempt. The goal is to reduce the chance of another suicidal crisis by providing structured support after discharge.
White Plains, New YorkAges 50–90 - NCT04621877Recruiting
Lay-led therapy for depression and anxiety at senior centers
This trial tests a structured, coach-led program called behavioral activation delivered in senior centers. It aims to improve symptoms of depression and generalized anxiety by teaching practical, step-by-step activity planning.
New York, New YorkAges 60 years+ - NCT07220460RecruitingPhase 2
Study of an oral drug for bipolar depression
This trial tests an experimental pill (ABB-932) for people with bipolar I or II disorder who are currently in a depressive episode. The goal is to see if the drug is safe and helps improve mood.
Brooklyn, New YorkAges 18–65 - NCT05574127RecruitingPhase 2
Behavioral therapy for depression in older cancer survivors
This trial tests a brief behavioral program to help older adults (65+) who have had cancer and are feeling depressed. It focuses on teaching simple, practical skills to improve mood and daily activity, delivered over video or phone.
New York, New YorkAges 65 years+ - NCT06455527Recruiting
Heart-guided brain stimulation for depression
This trial tests whether a non-invasive brain stimulation technique called tDCS, guided by your heart rate, can help improve depression symptoms. If you have mild to moderate depression and are not on medication, you may be eligible.
New York, New YorkAges 18–65 - NCT07188467Recruiting
Stress and well-being support for international students
This study tests a self-help program called 'SH+' designed to reduce stress and improve well-being in international students at The New School. If you are an international student feeling at least mildly distressed, this program may help you develop coping skills.
Brooklyn, New YorkAges 18 years+ - NCT07225088Recruiting
Mental health support for Latino cancer patients
This study tests a mental health intervention called DESCANSO to help Latino people with cancer who feel depressed, have trouble sleeping, or are very tired. You may join if you are a Latino adult with stage I-III solid tumor cancer, speak Spanish, and are currently or recently finished treatment.
Commack, New YorkAges 18 years+ - NCT06689878Recruiting
Mobile therapy for anxiety and depression after stroke
This study tests if a mobile cognitive behavioral therapy app can help reduce anxiety and depression in people who have had a stroke. If you are between 40 and 79 and have ongoing feelings of worry or low mood after your stroke, this therapy might be a convenient option.
New York, New YorkAges 40–79 - NCT06748222RecruitingPhase 3
Online mindfulness program for breast cancer survivors
This trial tests a 6-week online mindfulness program to help breast cancer survivors manage mild to moderate depression. You may qualify if you finished active treatment within the last 5 years and can use a digital device.
Astoria, New YorkAges 18–50 - NCT07717385Recruiting
90-day trial of a probiotic for stress and sleep
This study tests whether a daily probiotic capsule called Neuralli Mood can help adults who feel stressed, have trouble sleeping, or experience low mood. It lasts 90 days and involves taking two capsules each day and filling out online surveys.
New York, New YorkAges 18 years+ - NCT04300998Recruiting
CAR-T therapy study for older adults
This study looks at how well CAR-T cell therapy works and how safely it can be given to older adults. It is for people whose cancer or related blood condition has come back or did not respond, and who are receiving a standard (commercial) CAR-T product.
New York, New YorkAges 60 years+ - NCT04752618Recruiting
Support program for mothers with trauma and young children
This study offers a structured support program for mothers dealing with trauma symptoms like PTSD, aiming to improve wellbeing and support parenting. It also involves clinicians connected to the Safe Mothers, Safe Children program.
New York, New YorkAges 18 years+ - NCT06605105Enrolling by invitationPhase 3
Long-term extension trial of CYB003 for depression
This long-term study is for people who already completed an earlier trial of the experimental drug CYB003 for major depression and who stayed on their regular antidepressant. It looks at the safety and effects of taking CYB003 again over many months.
New York, New YorkAges 18–85 - NCT04940585Recruiting
Study for pregnant women with stress or depression symptoms
This study supports pregnant people who are in their second trimester and have signs of stress, trauma, or depression. The goal is to learn whether the program can help improve emotional well-being during pregnancy.
New York, New YorkAges 18–100 - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
Orangeburg, New YorkAges 60 years+ - NCT05447689Recruiting
Group mind-body skills for anxious graduate students
This trial offers a weekly group program teaching mind-body skills to help reduce anxiety. It’s for graduate students who screen as having moderate or higher anxiety and can attend meetings regularly.
White Plains, New YorkAges 18 years+ - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT05734313Recruiting
Teletherapy CBT for anxiety and depression in people with diabetes
This trial tests a unified, talk-therapy program delivered by video (telemedicine) to help with anxiety and depressive symptoms. If you have type 1 diabetes and symptoms of anxiety or depression, it may help you learn coping skills and improve mood.
The Bronx, New YorkAges 18–64 - NCT05779761Recruiting
Brief coping exercises for high distress and worry
This study tests brief coping interventions to help people who feel very worried, stuck in negative thoughts, or overly self-critical. You would likely complete short activities using your smartphone and internet while the study checks how your distress changes over time.
New York, New YorkAges 18–65 - NCT05800925Recruiting
Triage survey to check who can join psychiatry research
This study uses a short questionnaire to figure out who is eligible to join future psychiatry research. It may help people get routed into studies that match their situation and safety needs.
New York, New YorkAges 18 years+ - NCT05833555Recruiting
Harlem Strong mental health support for adults
This program is for Black and Latino adults in Harlem who are dealing with mild to moderate depression symptoms. It aims to identify people who may benefit from mental health support and connect them with the right level of care.
New York, New YorkAges 18–65 - NCT05897619Recruiting
CBT skills app for pregnancy and postpartum stress and coping
This study tests whether a new phone app that teaches “cognitive behavioral therapy” (CBT) skills is helpful and easy to use for people who are pregnant or recently gave birth. It also checks safety and whether participants feel the app is acceptable to use over time.
New York, New YorkAges 18 years+ - NCT05922878RecruitingPhase 2
ALTO-300 study for moderate to severe depression
This trial tests ALTO-300 as an add-on treatment for people with moderate to severe major depressive disorder (MDD). It aims to see whether ALTO-300 helps improve depression symptoms when you’re already on a stable antidepressant.
Rochester, New YorkAges 18–70 - NCT06004414Recruiting
SilverCloud mental health app study for high school students
This study tests a mental health app called SilverCloud in high school students who are feeling anxious or depressed. It aims to see if the app can help improve their mood and wellbeing.
Brooklyn, New YorkAges 13–22
Depression trials by city in New York
Where these studies are running in New York
Institutions with a site for the recruiting depression studies listed above.
- Weill Cornell Medicine · 5 studies
- Memorial Sloan Kettering Cancer Center · 3 studies
- NYU Langone Health · 3 studies
- Adams Clinical Bronx · 2 studies
- Adams Clinical Harlem · 2 studies
- Albert Einstein College of Medicine
- Carver Senior Center
- CUNY Graduate School of Public Health and Health Policy
What taking part in a depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Depression trials in other states
Common questions
- Are there depression clinical trials in New York?
- Yes. We're currently tracking 110 recruiting depression studies with a site in New York, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a depression study in New York?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in New York to take part?
- Not necessarily. These studies have a site in New York, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New depression studies open in New York regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.