Clinical trials · Chicago, IL
Diabetes clinical trials in Chicago
We’re tracking 87 recruiting diabetes studies with a site in or near Chicago — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chicago, IllinoisAges 55 years+ - NCT06887049Recruiting
Screening for emotional health in type 2 diabetes
This study tests a program to regularly screen and support emotional health in adults with type 2 diabetes and high blood sugar (A1C greater than 8%). It aims to improve both emotional well-being and diabetes management.
Chicago, IllinoisAges 18 years+ - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Chicago, IllinoisAges 18–75 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Chicago, IllinoisAges 18 years+ - NCT07417865Recruiting
Diabetes care study for health centers
This study looks at how well diabetes care works at certain community health centers. If you are 18 or older and have diabetes, your data may help improve care for others like you.
Chicago, IllinoisAges 18 years+ - NCT06988306Recruiting
Lifestyle program to prevent diabetes after pregnancy
This study tests a lifestyle program (like diet and activity guidance) to help prevent diabetes after pregnancy in people who had gestational diabetes. You'll be part of a home visiting program and learn ways to stay healthy.
Chicago, IllinoisAges 18 years+ - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Chicago, IllinoisAges 18 years+ - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Chicago, IllinoisAges Any age - NCT05199454Recruiting
Study how “fat-like” particles affect blood vessel function
This study looks at whether tiny fat-based particles (“adiposomes”) can affect how well your blood vessels work, especially in people with diabetes and higher body weight. You may be asked to do moderate exercise and other study procedures after passing safety checks.
Chicago, IllinoisAges 18–50 - NCT06950788Recruiting
Glucose changes in cirrhosis patients around liver transplant
This study looks at how the body processes sugar (glucose) in people with cirrhosis who are waiting for a liver transplant. It aims to track changes in blood sugar control before and after transplant, which may help improve care for patients with liver disease.
Chicago, IllinoisAges 18–75 - NCT01630850Recruiting
Islet cell transplant for brittle type 1 diabetes
This trial studies whether transplanting insulin-producing islet cells can improve blood sugar control and reduce severe low blood sugar in people with “brittle” type 1 diabetes. It’s meant for adults with long-standing insulin dependence and troublesome, hard-to-control hypoglycemia.
Chicago, IllinoisAges 18–70 - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Chicago, IllinoisAges 18 years+ - NCT07271186RecruitingPhase 2
Study of a New Drug for Diabetic Kidney Disease
This study tests an investigational drug that blocks a protein called ANGPTL3, which may help protect the kidneys in people with type 2 diabetes and diabetic kidney disease. It aims to see if the drug can reduce kidney damage and improve overall health.
Chicago, IllinoisAges 18–80 - NCT06517576Enrolling by invitation
Remote monitoring for type 2 diabetes
This trial tests using a smartphone to help manage your blood sugar. It's for people with type 2 diabetes who take insulin and whose blood sugar is not well controlled (HbA1c 8% or higher).
Chicago, IllinoisAges 18 years+ - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Chicago, IllinoisAges 12–35 - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Chicago, IllinoisAges 18 years+ - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Chicago, IllinoisAges 18–50 - NCT06986161Recruiting
How eating mangoes at different times affects blood sugar
This study tests whether eating mangoes at breakfast or as a snack helps control blood sugar better. It's for people with prediabetes who want to see if fruit timing can improve their health.
Chicago, IllinoisAges 20–60 - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT07091318RecruitingEarly Phase 1
CBT for insomnia in type 1 diabetes
This study tests whether cognitive behavioral therapy for insomnia (CBTi) can improve sleep in people with type 1 diabetes. It may help those who have poor sleep quality and use a continuous glucose monitor.
Chicago, IllinoisAges 18–65 - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
Chicago, IllinoisAges 18 years+ - NCT06555952Recruiting
Grape seed extract for blood pressure and heart health
This trial tests whether a grape seed extract can help lower blood pressure in people with mildly high blood pressure and slightly elevated blood sugar. It's designed for adults aged 40-60 who are not on blood pressure or diabetes medications.
Chicago, IllinoisAges 40–60 - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Chicago, IllinoisAges 18 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+
Hear when a new Diabetes trial opens near Chicago, IL
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Diabetes trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting diabetes studies listed above.
- University of Chicago · 6 studies
- Northwestern University · 5 studies
- University of Illinois · 3 studies
- Clinical Nutrition Research Center · 2 studies
- Research Site · 2 studies
- Accellacare - Duly Health and Care
- Accellacare of Duly Health and Care
- Alliance for Clinical Trials in Oncology
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting diabetes studies in Illinois.
Common questions
- Are there diabetes clinical trials near Chicago?
- Yes. We're currently tracking 87 recruiting diabetes studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.