Clinical trials
Disc Disease clinical trials
Below are recruiting disc disease clinical trials, each written for real people, not researchers. We’re tracking 76 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06209684Recruiting
Carbon fiber screws vs titanium for spine surgery
This trial compares a new carbon fiber screw system to standard titanium screws for people needing spinal fusion surgery to treat degenerative spine conditions. It aims to see which type of screw works better for pain and stability.
BolognaAges 18 years+ - NCT06704919Recruiting
Spinal fusion using conduit cages and bone graft putty
This trial tests a new combination of a cage and bone graft putty for spinal fusion surgery. It is for people with degenerative disc disease or a herniated disc in the neck or lower back that needs surgery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07168603RecruitingPhase 1/Phase 2
Testing own disc cells for low back pain from a herniated disc
This trial tests whether your own disc cells (nucleus pulposus cells) can help heal a herniated disc and reduce pain. It is for people who have had low back pain for more than six weeks and are scheduled for disc surgery.
TaipeiAges 20 years+ - NCT06011551Recruiting
Gel injection for painful lumbar discs
This trial tests a gel (HYDRAFIL-D) injected into painful discs in your lower back to see if it relieves pain. It's for people whose back pain hasn't improved with other treatments.
Birmingham, AlabamaAges 22–85 - NCT04631133Recruiting
Study of outcomes after surgery using the LISA implant
This study follows adults who get back surgery using the LISA implant to see how well they do afterward and how outcomes change over time. It focuses on people whose long-term, non-surgical care did not relieve low-back pain from specific age-related disc changes.
SilkeborgAges 18 years+ - NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT05701059Recruiting
Tests different artificial discs for neck nerve and spinal cord problems
This trial compares two types of artificial disc implants used for certain neck problems. It may help people who have tried non-surgical treatments but still have ongoing nerve symptoms or spinal cord issues from a damaged disc in the neck.
Los Angeles, CaliforniaAges 18–60 - NCT07338877Enrolling by invitation
Stem cell therapy for disc-related low back pain
This trial tests a new treatment that uses your own stem cells to help heal damaged discs in your lower back. The stem cells are injected into the disc during a minimally invasive procedure to reduce pain and improve function.
Košice, Košice RegionAges 18 years+ - NCT07001969Enrolling by invitation
Percutaneous facet spine fixation for instability
This study tests a minimally invasive procedure to fix unstable vertebrae in the neck or lower back using a small incision. It may help people with spinal instability causing nerve symptoms or pressure on the spinal cord.
Cairo, ShoroukAges Any age - NCT05444751Enrolling by invitationPhase 3
Different pain medicine plans for back surgery
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
New York, New YorkAges 18–80 - NCT07368972RecruitingPhase 2
Study of DISC-0974-201 for IBD and Anemia
This trial tests a new medicine called DISC-0974-201 for people with inflammatory bowel disease and anemia. It aims to see if the drug can improve anemia symptoms and is for people with mild disease activity who have not responded well to standard treatments.
Scottsdale, ArizonaAges 18 years+ - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT05299762Recruiting
INFUSE bone graft for lower back fusion: patient follow-up study
This study tracks patients who receive INFUSE bone graft during a specific type of lower back fusion surgery. It helps confirm how the device performs in real-world care and monitors safety and outcomes after surgery.
SeoulAges 18 years+ - NCT07615491Recruiting
Safety and effectiveness study of spinal implants and bone materials
This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.
IzmirAges 18 years+ - NCT06240221Enrolling by invitation
Tracking real-world use of the Saber-C cervical fusion device
This registry tracks how the Saber-C implant works in real-life neck surgeries. It gathers information to help doctors understand outcomes for people like you.
Paducah, KentuckyAges 18 years+ - NCT07662668Recruiting
NSAID effect on periostin in back pain patients
This trial tests how a common anti-inflammatory drug (NSAID) affects a protein called periostin, which may be linked to spine problems. It could help people with herniated discs or spinal stenosis.
DaeguAges 20–80 - NCT07664904Recruiting
Periostin protein levels and quality of life in back pain patients
This study looks at how a protein called periostin relates to back function and quality of life in people with disc herniations or spinal stenosis. You'll fill out two questionnaires and have your periostin measured from a blood draw or MRI.
Daegu, DaeguAges 20–80 - NCT07222787Recruiting
Testing a new spinal implant for lower back fusion
This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.
Scottsdale, ArizonaAges 18–80 - NCT06029764Recruiting
Extended fusion for spinal disc vacuum signs
This trial tests a surgery that fuses one extra spinal disc to treat a 'vacuum sign' (air pockets in the disc) that hasn't caused symptoms yet. It aims to prevent future problems in people with lumbar disc disease who need fusion surgery.
Beijing, Beijing MunicipalityAges 18–60 - NCT07250126Recruiting
3D printed spine model for spinal surgery
This trial is testing a new 3D-printed model of the spine to help plan surgeries. It may offer a more personalized approach to spine care.
Milan, MIAges 30–70 - NCT05296889Recruiting
Safety follow-up for Ennovate cervical device
This study checks how safely and effectively a cervical device (Ennovate® Cervical) works after it’s been used in routine care. It may help by monitoring real-world safety and performance over time.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT04388332Recruiting
Neck surgery compares two bone graft materials
This study compares two materials used during neck surgery for degenerative disc disease: donor bone (structural allograft) versus a titanium cage (Tritanium C). It aims to see which option works better for healing the fused neck bones and improving symptoms.
Pittsburgh, PennsylvaniaAges 18–80 - NCT04467944Recruiting
Lumbar fusion outcomes with arthritis in nearby spine segments
This study looks at how well lumbar fusion surgery works long-term when the joint just above or below (adjacent segment) already shows wear-and-tear. It may help predict who benefits most and guide treatment planning.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for disc disease?
- Yes. Clin2 currently lists 76 recruiting disc disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disc disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disc disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.