Clinical trials
Heart Diseases clinical trials
Below are recruiting heart diseases clinical trials, each written for real people, not researchers. We’re tracking 734 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT02306200Recruiting
A study to improve heart and aorta health
This trial looks at ways to improve cardiovascular (heart and blood vessel) health, especially conditions that affect the aorta, such as aneurysms, or vascular problems that may run in families. If you have an aortic-related or other cardiovascular diagnosis (or you’re a healthy comparison participant), you may be invited to take part in this health-improvement program.
Ann Arbor, MichiganAges Any age - NCT00471250Recruiting
Lung fluid and tissue sample collection for research
This study collects samples from your lungs and airways to help researchers better understand lung diseases. It is not a treatment study, but your participation could help improve future care for people with lung conditions.
Bethesda, MarylandAges 5–100 - NCT05904093RecruitingPhase 1
Testing a new pill for sickle cell disease safety
This study tests a medication called fostamatinib to see if it is safe and tolerable for people with sickle cell disease. It may offer a new treatment option for managing the condition.
Bethesda, MarylandAges 18–65 - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT07023666RecruitingPhase 2
Early heart screening and treatment for sickle cell disease
This trial tests early screening and treatment to prevent heart problems in people with sickle cell disease. It focuses on those with high iron levels or heart symptoms, using regular heart imaging to monitor and treat complications early.
Fairfax, VirginiaAges 18 years+ - NCT06009276Recruiting
Gut bacteria, muscle blood flow, and fitness study
This study looks at how the bacteria in your gut affect blood flow to your muscles and your overall fitness. You will provide samples and do some exercise tests to help researchers understand this link.
Charlottesville, VirginiaAges 18 years+ - NCT05775445Recruiting
People with very blocked or very normal coronary arteries
This study compares people with very severe coronary artery disease to those without significant disease, using heart imaging data. It aims to understand what differs between extreme cases and how that information could guide future care.
SingaporeAges 21–99 - NCT05958706Recruiting
Testing how heart cells use fuel in heart failure
This study looks at how the heart uses energy fuel in people with heart failure, including those with type 2 diabetes. It may help researchers understand what’s going on inside the heart and how it could be treated in the future.
DüsseldorfAges 20–85 - NCT07393412Recruiting
Heart and vessel disease study for Korean patients at Samsung Medical Center
This study looks at people who have visited Samsung Medical Center for heart or blood vessel problems. It aims to find what factors affect their health over time, which could help doctors predict and prevent future issues.
SeoulAges Any age - NCT07500610Recruiting
How inflammation affects heart and mobility in PAD
This study looks at how inflammation affects people with peripheral artery disease (PAD), and how it relates to heart health and walking ability. The goal is to understand these connections better, which could help doctors treat PAD more effectively.
Vancouver, British ColumbiaAges 19 years+ - NCT06813443Recruiting
Studying cardiomyopathy to find who needs a heart transplant
This study is looking at people with cardiomyopathy to understand which patients are most in need of a heart transplant. By joining, you will help doctors learn more about critical cases and improve care for heart muscle disease.
Bologna, Emilia-Romagna/BolognaAges 12 years+ - NCT05366153Recruiting
Plan to lower future heart attack risk after past cancer treatment
This trial tests whether a “risk-guided” care plan can help prevent coronary artery disease (the buildup that can lead to heart attacks) in people who had cancer treatment that can affect the heart. You may get closer heart risk monitoring and guidance to reduce risk factors, such as cholesterol—especially if you can safely take statins.
Hobart, TasmaniaAges 40–70 - NCT06512493Recruiting
South East Netherlands Heart Registry
This is a heart registry that collects information from all patients to get a complete picture of heart care in the region. By including everyone, it aims to improve future treatments without bias.
Heerlen, LimburgAges Any age - NCT07797335RecruitingPhase 3
Zenagamtide for diabetes and weight loss
This study compares a new once-weekly injection to lower blood sugar levels against a standard daily injection in people with type 2 diabetes who are at high risk for heart problems. It aims to find out if the new medicine is more effective in managing blood sugar and body weight.
Birmingham, AlabamaAges 45 years+ - NCT07643610Recruiting
Heart Failure Crisis Registry Study
This registry collects information from patients admitted to the hospital with cardiogenic shock—a serious condition where the heart cannot pump enough blood to the body. Doctors will gather data to better understand what happens to these patients and how to improve their care.
Basel, Canton of Basel-CityAges 18 years+ - NCT06706635Recruiting
Better info for aortic stenosis patients before TAVI
This trial tests whether giving extra information before heart valve replacement (TAVI) helps patients feel more informed and improves their reported outcomes. If you have severe aortic stenosis and are planning to get a TAVI, this study may be for you.
Bad OeynhausenAges 18 years+ - NCT07601867Recruiting
Dapagliflozin to improve heart function after bypass surgery
This trial tests whether a diabetes medication called dapagliflozin can help improve how well the right side of your heart works after off-pump coronary artery bypass grafting surgery (a way to reroute blood around blocked heart arteries). The goal is to see if this drug reduces strain on your heart during recovery.
Pyatigorsk, Stavropol KrayAges 18 years+ - NCT07482943RecruitingPhase 4
Dapagliflozin for heart function after Fontan procedure
This trial tests whether dapagliflozin, a diabetes drug that also helps the heart, can improve exercise ability and heart function in people who have had the Fontan procedure for a single ventricle heart defect.
Hong KongAges 12 years+ - NCT07259239Recruiting
Using sonic cracker to treat heart artery calcium buildup
This study tests a new device called a 'sonic cracker' (IVL) to break up hard calcium in your heart arteries during a planned angioplasty (PCI). It aims to see if this approach is safe and works well for people with moderate or heavy calcium buildup.
SingaporeAges 21 years+ - NCT07224685Recruiting
Mayo heart & voice health study with phone and watch
This study uses your iPhone and Apple Watch to collect heart and voice data to learn more about cardiovascular health. It may help improve how doctors monitor heart conditions.
Rochester, MinnesotaAges 18 years+ - NCT07078344RecruitingPhase 2
Omega-3 study for healthy African American and European American adults
This study tests whether taking omega-3 supplements can improve health and reduce diet-related differences between African American and European American adults. You would take daily capsules and visit the clinic regularly for about 6 months.
Tucson, ArizonaAges 18–64 - NCT06753227Enrolling by invitation
Comparing ways to measure valve pressure after TAVI
This trial looks at how well a new method (using echo) compares to the standard invasive method for measuring pressure across the new valve after TAVI. It may help doctors monitor your valve function with less risk.
Munich, BavariaAges 18 years+ - NCT06642272RecruitingPhase 4
Comparing two diabetes drugs in real-world use
This trial compares two common diabetes medications, empagliflozin and dapagliflozin, to see which works better in everyday practice. It aims to find the best treatment option for patients with type 2 diabetes.
CopenhagenAges 18 years+
Hear when a new Heart Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for heart diseases?
- Yes. Clin2 currently lists 734 recruiting heart diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.