Clinical trials · Ohio
High blood pressure clinical trials in Ohio
We’re tracking 43 recruiting high blood pressure studies with a site in Ohio — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT07511361RecruitingPhase 2
Tonlamarsen for high blood pressure after hospitalization
This study tests an investigational medication (Tonlamarsen) for people who were recently hospitalized for a very severe high blood pressure episode and also have heart or kidney disease. It aims to see if the drug can help control blood pressure after discharge.
Beavercreek, OhioAges 18 years+ - NCT04555161Recruiting
Test of an implanted device for pulmonary arterial hypertension
This trial studies an implanted system (the Aria CV Pulmonary Hypertension System) to treat pulmonary arterial hypertension, a serious lung-blood vessel and heart condition. It aims to see whether the device can improve outcomes for people who are still sick despite existing PH medicines.
Columbus, OhioAges 18 years+ - NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Cincinnati, OhioAges birth+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Cincinnati, OhioAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Columbus, OhioAges 18–80 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Cleveland, OhioAges 18–85 - NCT07090161RecruitingPhase 2
Study of iloperidone for uncontrolled high blood pressure
This trial tests if iloperidone can lower blood pressure in people whose high blood pressure is not controlled by current medications. You may qualify if your blood pressure is still high after weeks of treatment.
Cincinnati, OhioAges 18–65 - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Columbus, OhioAges 14–35 - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Columbus, OhioAges 18 years+ - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Cincinnati, OhioAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Beavercreek, OhioAges 18 years+ - NCT07363343Recruiting
Blood pressure medication study for new mothers after birth
This study tests two different drug combinations to see which works better for new mothers with postpartum high blood pressure that needs more than one medication.
Cleveland, OhioAges 18 years+ - NCT07365332RecruitingPhase 3
IKT-001 for pulmonary arterial hypertension
This study tests a new medicine called IKT-001 for people with pulmonary arterial hypertension (PAH). It aims to see if IKT-001 helps improve exercise ability and other symptoms when added to current PAH therapies.
Cincinnati, OhioAges 18–75 - NCT07318597RecruitingPhase 2
A study of an experimental drug for pulmonary arterial hypertension
This trial tests a new medication called REGN13335 for people with pulmonary arterial hypertension (PAH). It aims to see if the drug can improve symptoms and function compared to standard care alone.
Cincinnati, OhioAges 18 years+ - NCT02249923Recruiting
Children with pulmonary hypertension registry in Spanish or English
This registry study collects information from children and families affected by pulmonary hypertension to better understand the condition. It may help researchers track outcomes over time and improve future care.
Cincinnati, OhioAges 1 day–21 years - NCT07232017Recruiting
Intensive blood pressure management study at Cleveland Clinic
This trial tests a program to help people with high blood pressure get it under better control. If you have high blood pressure that is not well-managed, this study may offer extra support and monitoring.
Cleveland, OhioAges 18–85 - NCT07209254Recruiting
Two smartphone plans to manage high blood pressure after childbirth
This study tests whether two different mobile-health tools can help new mothers keep their blood pressure under control in the first weeks after giving birth. It is designed for women who were diagnosed with a blood pressure condition during pregnancy and need medication after delivery.
Columbus, OhioAges 18 years+ - NCT07179380RecruitingPhase 3
Inhaled treprostinil for pulmonary hypertension related to interstitial lung disease
This study tests an inhaled powder medication called TPIP (treprostinil palmitil inhalation powder) to see if it can improve symptoms and exercise ability in people who have both interstitial lung disease and pulmonary hypertension. The study will compare TPIP against a placebo (a dummy treatment without the active drug) to understand how well it works and if it is safe.
Cincinnati, OhioAges 18 years+ - NCT07142356RecruitingPhase 2
New oral medication for high blood pressure not controlled by current pills
This study tests a new medication, RTN-001, for people whose blood pressure remains high even when taking multiple blood pressure medications. The goal is to see if this drug can lower blood pressure more effectively.
Cincinnati, OhioAges 18–75 - NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT06992440RecruitingPhase 2
Empagliflozin for better right heart function in pulmonary hypertension
This trial tests if a diabetes drug can help people with pulmonary arterial hypertension whose right heart function is reduced. Participants take empagliflozin or a placebo for 24 weeks to see if heart function improves.
Cleveland, OhioAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Cleveland, OhioAges 18 years+ - NCT06632379RecruitingPhase 4
Atorvastatin after pregnancy to lower heart risk
This trial tests if taking atorvastatin, a common cholesterol medication, after delivery can reduce future heart problems in women who had high blood pressure or preeclampsia during pregnancy. It lasts for 6 months and includes participants who are at least 20 years old.
Columbus, OhioAges 20–50 - NCT05587712RecruitingPhase 2
Sotatercept trial for children with pulmonary arterial hypertension
This Phase 2 trial tests sotatercept, a medicine that targets the blood-vessel changes in pulmonary arterial hypertension (PAH), in children. It may help improve how well the heart and lungs work by changing the underlying disease process.
Cincinnati, OhioAges 1–17
High blood pressure trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting high blood pressure studies listed above.
- Cleveland Clinic · 6 studies
- The Ohio State University · 4 studies
- The Ohio State University Wexner Medical Center · 2 studies
- University Hospitals Cleveland Medical Center · 2 studies
- University of Cincinnati · 2 studies
- Cincinnati Children's Hospital
- Cincinnati Children's Hospital Medical Center
- Cincinnati Children's Hospital Medical Center ( Site 1602)
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in Ohio?
- Yes. We're currently tracking 43 recruiting high blood pressure studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.