Clinical trials · California
High blood pressure clinical trials in California
We’re tracking 67 recruiting high blood pressure studies with a site in California — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Santa Barbara, CaliforniaAges birth+ - NCT04555161Recruiting
Test of an implanted device for pulmonary arterial hypertension
This trial studies an implanted system (the Aria CV Pulmonary Hypertension System) to treat pulmonary arterial hypertension, a serious lung-blood vessel and heart condition. It aims to see whether the device can improve outcomes for people who are still sick despite existing PH medicines.
Los Angeles, CaliforniaAges 18 years+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
La Jolla, CaliforniaAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Rancho Cordova, CaliforniaAges 18–80 - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Los Angeles, CaliforniaAges 18 years+ - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Los Angeles, CaliforniaAges 14–35 - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Glendale, CaliforniaAges 18 years+ - NCT07090161RecruitingPhase 2
Study of iloperidone for uncontrolled high blood pressure
This trial tests if iloperidone can lower blood pressure in people whose high blood pressure is not controlled by current medications. You may qualify if your blood pressure is still high after weeks of treatment.
Chula Vista, CaliforniaAges 18–65 - NCT07780500Recruiting
Using electronic health records to study people with high blood pressure
This study is not testing a new medicine. Instead, it is using electronic health records to better understand people with high blood pressure, with a focus on those recently diagnosed. If you join, you may help researchers learn more about how to improve care for others with high blood pressure.
Oakland, CaliforniaAges 18 years+ - NCT07218029RecruitingPhase 3
Long-term study of sotatercept for PAH
This study is for people who have already taken part in a clinical trial of sotatercept for pulmonary arterial hypertension and done well enough to continue. It tests the long-term safety and effectiveness of staying on sotatercept, an investigational treatment that helps lower blood pressure in the lungs.
La Jolla, CaliforniaAges 18 years+ - NCT06871462Enrolling by invitation
Texting program to help monitor blood pressure at home
This study tests a program that uses text messages to help people with high blood pressure check and manage their blood pressure at home. It may help you better control your blood pressure and reduce health risks.
San Francisco, CaliforniaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Los Angeles, CaliforniaAges birth–20 years - NCT07481981RecruitingPhase 3
Study of once-daily inhaled TPIP for pulmonary arterial hypertension
This trial tests an inhaled medication (TPIP) that opens blood vessels in the lungs to help you breathe easier and be more active. It is for people with PAH who are already on stable treatment and have moderate symptoms.
Santa Barbara, CaliforniaAges 18–75 - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Beverly Hills, CaliforniaAges 18 years+ - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT07179380RecruitingPhase 3
A study of an inhaled drug for lung disease with high blood pressure
This trial tests an inhaled medicine (TPIP) for people with both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug helps improve exercise ability and symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT06526858Recruiting
Laparoscopic kidney nerve treatment for resistant hypertension
This study tests a new treatment called HyperQure RDN, a laparoscopic (keyhole) surgery that targets nerves near the kidneys to lower blood pressure in people with resistant hypertension. If you have tried multiple medications but your blood pressure is still high, this procedure might offer an alternative approach.
Orange, CaliforniaAges 22–80 - NCT06343298RecruitingPhase 2
Testing MANP for hard-to-control high blood pressure
This trial tests a new drug called MANP for people whose blood pressure stays high despite taking three or more different types of blood pressure medications. The goal is to see if MANP is safe and effective in lowering blood pressure.
Valencia, CaliforniaAges 18–80 - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Garden Grove, CaliforniaAges 18 years+ - NCT07473700RecruitingPhase 2
Study of TX000045 for lung scarring and high blood pressure in the lungs
This trial tests a new medicine called TX000045 for people who have both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug can help improve breathing and daily function.
San Francisco, CaliforniaAges 18–80 - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Valley Village, CaliforniaAges 22 years+ - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Petaluma, CaliforniaAges 18 years+ - NCT05479461Recruiting
Phone-based blood pressure care vs usual care
This trial tests whether a technology-enabled program (using a smartphone) helps lower blood pressure better than standard care. It may help you manage high blood pressure with guided treatment changes.
Palo Alto, CaliforniaAges 30–90 - NCT05530512Recruiting
Acupuncture for mild to moderate high blood pressure
This study tests whether acupuncture can help lower blood pressure in people with mild to moderate hypertension. You may be asked to join because you meet age and blood-pressure ranges and have a normal heart screening ECG.
Orange, CaliforniaAges 45–75
High blood pressure trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting high blood pressure studies listed above.
- University of California, Davis Medical Center · 4 studies
- University of California, Irvine Medical Center / UC Irvine Health · 4 studies
- Stanford University · 3 studies
- University of California, Los Angeles (UCLA) · 3 studies
- Cedars-Sinai Medical Center · 2 studies
- Cottage Health System · 2 studies
- UC San Diego Health · 2 studies
- University of California, San Francisco · 2 studies
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in California?
- Yes. We're currently tracking 67 recruiting high blood pressure studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.