Clinical trials · Illinois
High blood pressure clinical trials in Illinois
We’re tracking 46 recruiting high blood pressure studies with a site in Illinois — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Elk Grove Village, IllinoisAges 18 years+ - NCT06899750Recruiting
E3 Hypertension: A team program for blood pressure control
This study tests a team-based program to help African American and Latinx people with uncontrolled high blood pressure. You'll use a smartphone app and get extra support from a doctor team to manage your blood pressure better.
Chicago, IllinoisAges 18 years+ - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Chicago, IllinoisAges 18 years+ - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Chicago, IllinoisAges 14–35 - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Chicago, IllinoisAges 18 years+ - NCT07090161RecruitingPhase 2
Study of iloperidone for uncontrolled high blood pressure
This trial tests if iloperidone can lower blood pressure in people whose high blood pressure is not controlled by current medications. You may qualify if your blood pressure is still high after weeks of treatment.
Oak Brook, IllinoisAges 18–65 - NCT07547345Recruiting
Community blood pressure help for adults
This pilot study aims to improve access to blood pressure management in community settings. If you have elevated blood pressure readings, this trial may help connect you with resources and support to manage your health.
Chicago, IllinoisAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Chicago, IllinoisAges birth–20 years - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Arlington Heights, IllinoisAges 18 years+ - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06343298RecruitingPhase 2
Testing MANP for hard-to-control high blood pressure
This trial tests a new drug called MANP for people whose blood pressure stays high despite taking three or more different types of blood pressure medications. The goal is to see if MANP is safe and effective in lowering blood pressure.
Chicago, IllinoisAges 18–80 - NCT07450222Enrolling by invitation
Improving high blood pressure care
This trial studies a new way to help people with high blood pressure get better control of their numbers. It uses a team approach to support you in managing your blood pressure and lowering your risk for heart problems.
Peoria, IllinoisAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Chicago, IllinoisAges 18 years+ - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Chicago, IllinoisAges 18 years+ - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Chicago, IllinoisAges 22 years+ - NCT06220721Recruiting
Preventing long-term high blood pressure after preeclampsia
This trial is testing a medication called nifedipine (a long-acting blood pressure pill) to see if it can help lower the risk of long-term high blood pressure and improve blood vessel health after a pregnancy complication like preeclampsia. It is for women who have just given birth and are still in the hospital.
Chicago, IllinoisAges 18 years+ - NCT06307574Recruiting
Smartphone study to help older adults manage blood pressure medication
This study tests a digital tool called bpMedManage to help adults aged 60 and older remember and manage their blood pressure medications. It's for people who have some memory or thinking challenges and use a smartphone.
Champaign, IllinoisAges 60 years+ - NCT07332741RecruitingPhase 2
Food as medicine for better blood pressure
This study tests a program that provides healthy food and support to help people with high blood pressure and a BMI of 30 or higher eat better and control their blood pressure. If you join, you'll get guidance on the DASH diet (a heart-healthy eating plan) and text messages to help you stay on track.
Chicago, IllinoisAges Any age - NCT06466161Recruiting
Testing a new blood pressure measurement method in pregnant patients
This study is testing a new way to measure blood pressure on your forearm and upper arm. It aims to see if this method works well for pregnant patients, especially those with high blood pressure conditions.
Chicago, IllinoisAges 18 years+ - NCT06559891Recruiting
Ultrasound treatment for high blood pressure
This trial tests an ultrasound device that targets nerves around the kidney to lower blood pressure. It may help people whose blood pressure is not well controlled with medication.
Elk Grove Village, IllinoisAges 22–75 - NCT07087613Recruiting
Detecting heart and lung pressure problems with a smart stethoscope
This study tests if a digital stethoscope and a simple 3-lead ECG (heart rhythm test) can detect two heart conditions: high blood pressure in the lungs (pulmonary hypertension) and low pumping strength of the heart (low ejection fraction). It's intended for adults who recently had a heart ultrasound or a heart catheterization.
Springfield, IllinoisAges 18 years+ - NCT07397260Enrolling by invitation
Home blood pressure monitoring and feedback for hypertension
This trial tests whether sending your home blood pressure readings to your doctor and getting automatic feedback helps manage high blood pressure. You'll use a blood pressure monitor at home and share results through a patient portal.
Chicago, IllinoisAges 18–84 - NCT06052072Enrolling by invitation
Heart failure trial testing nerve treatment for lung pressure
This trial tests a new treatment that uses a device to calm overactive nerves in the lung's blood vessels. It is for heart failure patients who also have high blood pressure in their lungs, to see if it can help them breathe easier and feel better.
Chicago, IllinoisAges 22–85 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Chicago, IllinoisAges 18 years+
High blood pressure trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting high blood pressure studies listed above.
- Northwestern University · 7 studies
- Cedar Crosse Research Center · 3 studies
- Ascension Alexian Brothers · 2 studies
- Rush University Medical Center · 2 studies
- University of Chicago · 2 studies
- Accellacare - Duly Health and Care
- Accellacare of Duly Health and Care
- Advocate Christ Medical Center
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in Illinois?
- Yes. We're currently tracking 46 recruiting high blood pressure studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.