Clinical trials · Pennsylvania
High blood pressure clinical trials in Pennsylvania
We’re tracking 50 recruiting high blood pressure studies with a site in Pennsylvania — including Early Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06642246Recruiting
Sleep Help for Kids with High Blood Pressure
This study tests whether helping teens with high blood pressure get more sleep can lower their blood pressure. It offers a sleep-focused program and checks if it helps within a few months.
Philadelphia, PennsylvaniaAges 13–18 - NCT06950099Recruiting
Advanced Brain Scans for IIH Patients Planning Stenting
This study uses advanced brain scans (MRIs) to look at the veins in your brain to help plan a stenting procedure for patients with Idiopathic Intracranial Hypertension (IIH) that is not improving with standard care.
Philadelphia, PennsylvaniaAges 18–55 - NCT07041281RecruitingPhase 2
Spironolactone to improve postpartum blood pressure after pregnancy hypertension
This study tests whether the medication spironolactone can help manage high blood pressure after delivery in people who had gestational hypertension or preeclampsia. It may help prevent long-term heart problems.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07151768Recruiting
Validating a risk score for lung disease patients with pulmonary hypertension
This study is testing whether a new risk score can better predict outcomes for people who have both chronic lung disease and pulmonary hypertension (high blood pressure in the lungs). If you qualify, the researchers will follow your health over time to see how well the score works.
Philadelphia, PennsylvaniaAges 18–99 - NCT07209254Recruiting
Two smartphone plans to manage high blood pressure after childbirth
This study tests whether two different mobile-health tools can help new mothers keep their blood pressure under control in the first weeks after giving birth. It is designed for women who were diagnosed with a blood pressure condition during pregnancy and need medication after delivery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02249923Recruiting
Children with pulmonary hypertension registry in Spanish or English
This registry study collects information from children and families affected by pulmonary hypertension to better understand the condition. It may help researchers track outcomes over time and improve future care.
Philadelphia, PennsylvaniaAges 1 day–21 years - NCT07298694Enrolling by invitation
Choosing a hypertension medication with helpful defaults
This trial tests whether changing the default options in doctors' ordering systems can help patients get the best medication for high blood pressure. You may be eligible if you are an adult who recently received a prescription for a common blood pressure drug at a participating clinic.
Danville, PennsylvaniaAges 18 years+ - NCT06211413Enrolling by invitation
Tracking heart issues in CLL patients on BTK inhibitors
This study watches for high blood pressure and irregular heartbeats in people with CLL who are starting a type of targeted therapy called a BTK inhibitor (acalabrutinib or zanubrutinib). Researchers will use a smartwatch and blood pressure cuff to monitor your heart health at home.
Philadelphia, PennsylvaniaAges 22 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Beaver, PennsylvaniaAges 18 years+ - NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Allentown, PennsylvaniaAges 18–85 - NCT03630211RecruitingPhase 2
Study of stem cell transplant for systemic sclerosis in youth
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
Pittsburgh, PennsylvaniaAges 8–60 - NCT06297291Recruiting
Long-term safety study for a kidney nerve treatment
This study tests a device that uses ultrasound to calm overactive kidney nerves, which may help lower blood pressure. It is for people with high blood pressure that is hard to control with medication.
Harrisburg, PennsylvaniaAges 18 years+ - NCT03496792Recruiting
Study of blood pressure changes when standing up
This study checks how your blood pressure changes when you go from lying down to standing. It may help researchers understand why some people get “orthostatic hypertension” (higher blood pressure when standing) and how that reflex works.
Hershey, PennsylvaniaAges 18 years+ - NCT06274801RecruitingPhase 3
Long-term study of seralutinib for pulmonary arterial hypertension
This trial is for people with pulmonary arterial hypertension (PAH) who have already completed a previous study of the drug seralutinib. It offers continued access to the treatment so doctors can watch its safety and effects over a longer time.
Philadelphia, PennsylvaniaAges 18–75 - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Bridgeville, PennsylvaniaAges 18 years+ - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Pittsburgh, PennsylvaniaAges 18–100 - NCT04967989RecruitingPhase 3
Laser eye treatment timing for certain glaucoma or eye pressure
This Phase 3 study tests how best to use a laser treatment (SLT) for people with high eye pressure or mild-to-moderate primary open-angle glaucoma. It aims to find the best way to lower eye pressure and protect vision while comparing treatment approaches.
Kingston, PennsylvaniaAges 18 years+ - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT06062394Recruiting
Healthy Heart study for Penn Medicine patients
This trial tests if a combination of medication and lifestyle changes can lower cholesterol and prevent heart problems in people who are at risk or already have heart disease.
Philadelphia, PennsylvaniaAges 35–80 - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Hershey, PennsylvaniaAges 18 years+ - NCT06605807Recruiting
Improving medication decisions for older adults in the hospital
This study examines how doctors prescribe medications for older adults with chronic conditions during their hospital stay. The goal is to learn how to make safer and more effective prescribing choices for patients aged 65 and older who are discharged home.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT07222917RecruitingPhase 2
Dapagliflozin with baxdrostat for kidney disease and high blood pressure
This trial tests if adding dapagliflozin to baxdrostat (a new blood pressure drug) reduces protein in urine better than baxdrostat alone in people with chronic kidney disease and high blood pressure. It aims to find a more effective way to protect kidney health.
Media, PennsylvaniaAges 18 years+
High blood pressure trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting high blood pressure studies listed above.
- University of Pennsylvania · 6 studies
- Allegheny General Hospital · 2 studies
- Children's Hospital of Philadelphia · 2 studies
- Penn State Milton S Hershey Medical Center · 2 studies
- Research Site · 2 studies
- Temple University Hospital · 2 studies
- Thomas Jefferson University Hospital · 2 studies
- Abington Memorial Hospital
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in Pennsylvania?
- Yes. We're currently tracking 50 recruiting high blood pressure studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.