Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06391073Recruiting
Testing a text program for high blood pressure after the ER
This study tests a text-message program to help people with high blood pressure manage their health after leaving the emergency department. If you qualify, you'll get tips and reminders on your phone to keep your blood pressure under control.
Flint, MichiganAges 18–99 - NCT06373289Recruiting
Blood pressure in lung arteries and oxygen levels in preemies
This study tests whether changing oxygen targets in preterm infants with high blood pressure in the lungs (pulmonary hypertension) helps their heart and lungs work better. It may help doctors find the best oxygen levels for these babies.
Birmingham, AlabamaAges 1 month–5 months - NCT06343298RecruitingPhase 2
Study of manp for hard-to-control high blood pressure
This study tests a new investigational drug called MANP to see if it can lower blood pressure in people whose blood pressure stays high even when they are already taking several medications. If it works, this drug might offer a new option for people with difficult-to-control hypertension.
Little Rock, ArkansasAges 18–80 - NCT06351345RecruitingPhase 2
Xenon imaging study for pulmonary hypertension patients on sotatercept
This trial uses a special imaging technique (xenon MRI) to see how well the lungs are functioning in people with pulmonary arterial hypertension (PAH) who are being treated with the drug sotatercept. It aims to understand if the drug improves lung function.
Durham, North CarolinaAges 18–75 - NCT06335433Recruiting
Handgrip exercise frequency and blood pressure in hypertension
This study tests whether doing handgrip exercises (squeezing a device in your hand) can help lower blood pressure. You can join if your blood pressure is on the higher side, you've been on the same medications (if any) for at least 4 months, and you're generally healthy enough to exercise.
Swansea, WalesAges 18–65 - NCT06336798RecruitingPhase 2
Pioglitazone for pulmonary hypertension from lung disease
This trial tests if pioglitazone, a medicine used for diabetes, can help people with high blood pressure in their lungs caused by chronic lung disease. The goal is to see if it improves how your cells use energy.
Atlanta, GeorgiaAges 18 years+ - NCT06316869Recruiting
Ultrasound test for high blood pressure in cirrhosis
This study tests a new, painless ultrasound method to check for high blood pressure in the liver's main blood vessel. It aims to avoid more invasive tests for people with cirrhosis. It might help doctors tell if you are at risk of bleeding without a catheter procedure.
Wenzhou, ZhejiangAges 18 years+ - NCT06307574Recruiting
Smartphone study to help older adults manage blood pressure medication
This study tests a digital tool called bpMedManage to help adults aged 60 and older remember and manage their blood pressure medications. It's for people who have some memory or thinking challenges and use a smartphone.
Tucson, ArizonaAges 60 years+ - NCT06283758Recruiting
Ultrasound treatment for kidney fat to lower blood pressure
This trial tests a new ultrasound treatment that targets the fat pad around your kidney to lower blood pressure. It might be an option if your blood pressure is still high despite medication and you meet the size requirements for the fat pad.
Nanjing, JiangsuAges 18–65 - NCT06288204Recruiting
Green Propolis and Royal Jelly for Kidney Health
This trial tests whether a supplement made from green propolis (a natural bee product) and royal jelly can help people with high blood pressure and chronic kidney disease. It aims to see if the supplement can improve kidney health and blood pressure control.
Rio de Janeiro, Rio de JaneiroAges 18–75 - NCT06246396RecruitingPhase 4
Minocycline for resistant high blood pressure
This study tests whether minocycline, a common antibiotic, can help lower blood pressure in people whose high blood pressure is not controlled by multiple medications. If you have resistant hypertension, this trial may offer a new option to better manage your condition.
Gainesville, FloridaAges 18–100 - NCT06211413Enrolling by invitation
Tracking heart issues in CLL patients on BTK inhibitors
This study watches for high blood pressure and irregular heartbeats in people with CLL who are starting a type of targeted therapy called a BTK inhibitor (acalabrutinib or zanubrutinib). Researchers will use a smartwatch and blood pressure cuff to monitor your heart health at home.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06220721Recruiting
Preventing long-term high blood pressure after preeclampsia
This trial is testing a medication called nifedipine (a long-acting blood pressure pill) to see if it can help lower the risk of long-term high blood pressure and improve blood vessel health after a pregnancy complication like preeclampsia. It is for women who have just given birth and are still in the hospital.
Chicago, IllinoisAges 18 years+ - NCT06205992Recruiting
Comparing 2D and 3D MRI scans for liver scarring and pressure
This study compares two types of MRI scans (2D and 3D) to see which is better at measuring liver scarring and high blood pressure in the liver's main vein. It is for people with cirrhosis who are already scheduled to have their liver vein pressure measured.
Shenyang, LiaoningAges 18–75 - NCT06081881Recruiting
High blood pressure in lungs after a severe blood clot
This study monitors people who had a severe lung blood clot to see if they develop high blood pressure in the lungs over time. It aims to catch the condition early, so treatment can start sooner.
AsyutAges 18–80 - NCT03312556Recruiting
CPAP for high blood pressure when lying down
This trial looks at whether using CPAP (a breathing device) can help control high blood pressure that happens when you lie down, in people with autonomic failure. It’s designed for safety and effectiveness and may improve symptoms and blood pressure control.
Nashville, TennesseeAges 18–85 - NCT06055452RecruitingPhase 4
SGLT2 Inhibitors for Pre-Heart Failure with Hypertension
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06052072Enrolling by invitation
Heart failure trial testing nerve treatment for lung pressure
This trial tests a new treatment that uses a device to calm overactive nerves in the lung's blood vessels. It is for heart failure patients who also have high blood pressure in their lungs, to see if it can help them breathe easier and feel better.
Chicago, IllinoisAges 22–85 - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT06002165Enrolling by invitation
Testing Ways to Improve Care for High Blood Pressure in Pregnancy
This study tests ways to help clinics follow a set of best practices for managing severe high blood pressure during and after pregnancy. It wants to see if the new approach helps clinics treat high blood pressure faster and more effectively.
Chapel Hill, North CarolinaAges birth–99 years - NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT05546931Recruiting
Mobile health program to help control high blood pressure
This study tests a phone-based (mobile) health program to help people in rural areas better control high blood pressure. It may help you track your readings and follow a plan that supports safer blood pressure over time.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05979168Recruiting
Text message program to help control high blood pressure in Nepal
This study tests whether receiving text messages on your phone can help Nepali adults with high blood pressure better control their condition. The program supports medication use and healthy habits through simple mobile messages.
Kathmandu, BagmatiAges 18–70 - NCT05989581RecruitingPhase 1
High blood pressure in early pregnancy treatment study
This study tests whether treating mild high blood pressure early in pregnancy (before 20 weeks) can improve outcomes for you and your baby. It compares taking medication versus monitoring without medication.
Birmingham, AlabamaAges 14–89
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.