Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05999851Recruiting
Maternal blood vessel health in pregnancy
This study looks at how well your blood vessels work during pregnancy to help predict high blood pressure disorders. If you join, you will have extra monitoring and blood tests.
BolognaAges 18–65 - NCT05942859Enrolling by invitation
AI study using heart ECGs to spot pulmonary hypertension
This study looks at patterns on a 12-lead ECG (a common heart tracing) to help diagnose pulmonary hypertension, using results from a right heart catheter test. It may help doctors use ECGs better in the future, without changing your current care.
BathAges 18 years+ - NCT05935605Recruiting
Study pulmonary hypertension in heart failure and valve disease
This study looks at pulmonary hypertension—high blood pressure in the lung arteries—in people with certain heart conditions (heart failure with preserved or reduced pumping function, or significant valve disease). It may help doctors better understand how lung blood pressure changes in these heart problems and guide care.
Rochester, MinnesotaAges 18 years+ - NCT05340023Recruiting
Test using lung scan patterns to diagnose a heart-lung condition
This study looks at patterns from specialized lung scan tests to help diagnose chronic thromboembolic pulmonary hypertension (a long-term problem with blood flow in the lungs after blood clots). If your results suggest this condition and you need a procedure to check heart pressure, you may be asked to join so the researchers can improve diagnosis.
Saint-EtienneAges 18 years+ - NCT05873387Recruiting
Stethoscope tool to detect pulmonary hypertension
This study tests a computer “listening” algorithm that uses an electronic stethoscope to help detect pulmonary hypertension. It may help spot this condition earlier by turning routine heart-lung exams into more informative screenings.
Providence, Rhode IslandAges 18 years+ - NCT05856591Recruiting
Food help and cooking skills for adults with high blood pressure
This study tests whether giving food resources plus hands-on kitchen skills can help adults who have food insecurity and high blood pressure. It may support healthier eating and routines that help manage blood pressure.
Indianapolis, IndianaAges 35–75 - NCT05834803Recruiting
Stenting narrowed kidney artery to help high-risk patients
This trial studies whether placing a small stent in a severely narrowed kidney artery can improve outcomes for people with high-risk, artery-hardening kidney blood-flow problems. It focuses on people whose high blood pressure or kidney function has been getting worse despite multiple medications.
Aarhus NAges 18 years+ - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT05835596Enrolling by invitation
App-based support to protect heart health after pregnancy
This trial tests whether a smartphone app (“MumCare”) can help improve or support cardiovascular (heart and blood vessel) health in people after certain pregnancy complications. It’s for new or recent moms who had pregnancy-related high blood pressure and/or gestational diabetes.
Oslo, OsloAges 18–50 - NCT05782556Recruiting
Freiburg TIPS Registry for portal hypertension patients
This is a registry study that collects information from people who need a procedure called TIPS for portal hypertension. It may help doctors better understand outcomes and care for both cirrhotic and non-cirrhotic causes of portal hypertension.
Freiburg im BreisgauAges 18–100 - NCT05780710Recruiting
Smartphone blood pressure monitor tested for people with high BP
This study compares an optical blood pressure monitor (used like a home device with a smartphone) against standard home blood pressure readings. It’s meant to see if the new device gives accurate results for people with high blood pressure who are not currently on blood pressure medicines.
Geneva, Canton of GenevaAges 21–85 - NCT05760898Recruiting
Helping control blood pressure in people with rheumatoid arthritis
This study aims to improve blood pressure control in adults who have both uncontrolled high blood pressure and rheumatoid arthritis. It may help by testing ways to better coordinate care between primary care and rheumatology.
Durham, North CarolinaAges 18 years+ - NCT05732727RecruitingPhase 3
Stronger BP lowering using diuretics in kidney disease
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
AngersAges 18 years+ - NCT05372263Recruiting
Tracking safety of pulmonary hypertension medicines by computer follow-up
This study checks how safe pulmonary hypertension–targeted medicines (and some calcium-blocking medicines) are over time. It uses a computer system to follow you after diagnosis, looking at outcomes and side effects.
Beijing, Beijing MunicipalityAges 3 months–85 years - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT05676476Recruiting
Tested extra blood-pressure control to extend pregnancy in preeclampsia
This trial studies whether using specific blood-pressure medicines can help people with non-severe preeclampsia stay pregnant longer. It aims to improve outcomes by treating blood pressure early while monitoring you and the baby closely.
Birmingham, AlabamaAges 14–49 - NCT05671406Recruiting
Digital game to help people manage high blood pressure
This study tests whether a sensor-controlled phone/tablet digital game can help people with high blood pressure better take care of their health at home. It may be helpful if you live in a Native American community and are willing to use the technology.
Chapel Hill, North CarolinaAges 18 years+ - NCT05593055RecruitingPhase 4
Test a heart and blood-pressure therapy in people with hypertension
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Boston, MassachusettsAges 18–75 - NCT05551104RecruitingPhase 3
Best blood pressure medicine after pregnancy
This study compares two common blood pressure medicines (nifedipine and labetalol) to see which is safest and works best for high blood pressure after childbirth. If you have postpartum hypertension, the trial may offer close monitoring and help doctors choose the safest option for you.
Loma Linda, CaliforniaAges 18 years+ - NCT05587712RecruitingPhase 2
Sotatercept trial for children with pulmonary arterial hypertension
This Phase 2 trial tests sotatercept, a medicine that targets the blood-vessel changes in pulmonary arterial hypertension (PAH), in children. It may help improve how well the heart and lungs work by changing the underlying disease process.
Los Angeles, CaliforniaAges 1–17 - NCT05508633Enrolling by invitationPhase 2
Alverine test to lower high pressure in the liver
This trial studies alverine to lower portal hypertension, which is high blood pressure in the liver that can happen with cirrhosis. If it works safely, it may reduce pressure-related complications in people with confirmed liver scarring.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05470205RecruitingPhase 3
Noninvasive blood-pressure measurement to estimate liver portal pressure
This Phase 3 study tests a noninvasive ultrasound-based method to estimate portal hypertension, which is high blood pressure in the liver’s blood vessels. It aims to help doctors measure how severe the liver circulation problem is without needing invasive pressure testing.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05464095Recruiting
Mobile health support for pulmonary arterial hypertension
This study tests whether using a mobile health tool can help people with pulmonary arterial hypertension (PAH) manage their condition in daily life. It’s aimed at adults who are stable on their PAH medicines and can track activity using a wearable device.
Nashville, TennesseeAges 18 years+ - NCT05489575Recruiting
CPAP machine for high blood pressure when lying down at night
This study tests whether using a CPAP breathing machine at night can lower high blood pressure that happens while you sleep. It targets people with nervous-system problems that affect blood pressure changes when standing.
Nashville, TennesseeAges 40–80
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.