Clinical trials
Mechanical Ventilation Complication clinical trials
Below are recruiting mechanical ventilation complication clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT06719258Recruiting
Trial on heated humidifiers for breathing tubes
This trial studies how heating and adding moisture to the air breathed through a breathing tube (called a heated humidifier) affects patients in intensive care. It focuses on people who need the breathing tube for a longer time or special protective settings.
Québec, QuebecAges 18 years+ - NCT05030337Recruiting
Closed-loop oxygen control for very preterm babies on ventilators
This trial tests a computer-guided (“closed-loop”) oxygen control system for very preterm babies who need breathing support. It aims to keep oxygen levels safer and more consistent than standard care.
LondonAges Any age - NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT05226247Recruiting
Check whether careful weaning prevents lung fluid buildup
This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.
DijonAges 18 years+ - NCT05371886Recruiting
Testing how morphine (with or without midazolam) behaves in NICU babies
This study measures how morphine works in very young babies, and whether adding midazolam changes how the medicines behave and affect the body. It may help doctors better choose and dose pain/sedation medicines for babies in intensive care.
BrestAges 5 months–10 months - NCT05536531Recruiting
NMES therapy to help prevent ICU muscle weakness
This trial tests whether a device that delivers small electrical pulses to muscles can help prevent breathing and muscle weakness in very sick ICU patients. It also looks at changes in blood markers that may relate to muscle weakness and recovery.
Santiago, Santiago MetropolitanAges 18 years+ - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT06184945Recruiting
Study of ICU staffing and support strategies
This study looks at how different staffing and support strategies may help patients who need a breathing machine in the ICU. Researchers want to see if these approaches can improve care and recovery.
Iowa City, IowaAges 19 years+ - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT06826794Recruiting
VentilO study for heart surgery patients on ventilators
This study tests a new way to monitor breathing in patients who are on a ventilator right after heart surgery. It may help doctors adjust settings more accurately.
Québec, QuebecAges 18 years+ - NCT05534243Recruiting
A breathing and brain-signal study for adults on ventilators
This study looks at brain activity during care for adults who are on a breathing machine through a tube in the windpipe. It may help doctors understand how to monitor recovery and guide care after intubation.
Iowa City, IowaAges 18 years+ - NCT07070843Recruiting
Comparing two eye care methods for ICU patients on ventilators
This study compares two different ways of caring for the eyes of intensive care patients on breathing machines. It aims to find which method better prevents eye problems like dryness or infection.
Istanbul, IstanbulAges 3 weeks+ - NCT06168162Recruiting
Personalized breathing support during weight-loss surgery
This trial tests whether a personalized breathing setting during surgery can lower the risk of lung complications after weight-loss surgery. If you have a high risk of lung issues, you may be eligible.
Cairo, Cairo GovernorateAges 16 years+ - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT07610824Recruiting
Lung Pressure and Recovery After Robot-Assisted Prostate Surgery
This study measures breathing pressure during robot-assisted prostate removal surgery and checks lung function after surgery using ultrasound. It aims to understand how surgery affects your lungs and recovery.
Ankara, AnkaraAges 18–80 - NCT04068012Recruiting
Test of a decision support tool for children with PARDS
This trial tests a computer “decision support” tool to help the care team manage treatment for children with PARDS who are just starting a breathing machine. It may help clinicians choose care steps and potentially support safer, more effective breathing management during the first days of ventilation.
Chicago, IllinoisAges 1 month–18 years - NCT06448988Enrolling by invitation
Lung function in two surgical positions
This study measures how well your lungs work while you are lying on your back versus in the side-lying park-bench position during brain or spine surgery. It aims to help doctors understand which position is easier for you to breathe in.
RomeAges 18 years+ - NCT04801589RecruitingPhase 3
Guided sedation for children on a breathing machine
This study tests a “goal-directed” approach to sedation (giving the right amount based on target goals) for children who need a breathing machine in the pediatric ICU. The goal is to reduce brain and recovery side effects while keeping children comfortable and safe.
Nashville, TennesseeAges 10 months–11 years - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT06367218Recruiting
Opioid-free anesthesia with spontaneous breathing for VATS lung nodule surgery
This trial tests a way to do VATS lung nodule surgery without using strong painkillers (opioids) and while you keep breathing on your own. It may help you recover faster with fewer side effects.
Wuhan, HubeiAges 18–70 - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT07239557Enrolling by invitation
Best timing for lung expansion moves during surgery
This trial tests different time intervals for a lung-opening technique (alveolar recruitment) during planned abdominal surgery, aiming to restore 90% of lung volume. It may help lower the risk of lung complications after surgery.
Guangzhou, GuangdongAges 65–80 - NCT07024420Recruiting
Sigh breathing during heart surgery with heart-lung machine
This study tests if adding occasional deep breaths (sighs) during heart surgery helps patients recover better after using the heart-lung machine. It is for people having planned (not emergency) heart surgery.
Nanjing, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilation complication?
- Yes. Clin2 currently lists 50 recruiting mechanical ventilation complication studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation complication trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation complication trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.