Clinical trials
Non-invasive Ventilation clinical trials
Below are recruiting non-invasive ventilation clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06987461Recruiting
Studying non-invasive ventilation for bronchiectasis
This trial is studying how a mask that helps you breathe (non-invasive ventilation) affects people with bronchiectasis (a condition where airways in the lungs are stretched and scarred). It may help doctors understand if this treatment improves quality of life or slows the disease.
CréteilAges 18 years+ - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years - NCT07047092RecruitingPhase 3
CPAP vs. NIV for sleep apnea in COPD after breathing failure
This trial compares two breathing devices (CPAP and NIV) for people with both COPD and sleep apnea who recently needed breathing help in the hospital. The goal is to see which device works better at preventing future breathing emergencies.
ParisAges 18–84 - NCT06996834Recruiting
Comparing breathing support methods for pneumonia-related breathing failure
This trial tests two noninvasive breathing support methods (NIV and HVNI) for people with pneumonia who are having trouble breathing. The goal is to see which method works better to help you avoid needing a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06989385Recruiting
Studying breathing support failure in respiratory failure
This study looks at why some patients with acute respiratory failure do not improve with non-invasive breathing support like high-flow nasal oxygen (HFNO) or non-invasive ventilation (NIV). It aims to find patterns that might predict when these treatments are not enough.
ModenaAges 18 years+ - NCT04220463Recruiting
Hypnosis during noninvasive breathing support for ICU lung illness
This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.
Rennes, Brittany RegionAges 18 years+ - NCT06735872Recruiting
Non-invasive breathing support for broken ribs and low oxygen
This trial tests if non-invasive breathing support (a mask that helps you breathe) can improve lung healing in people with broken ribs from chest trauma who need extra oxygen. It aims to see if this treatment helps avoid the need for a breathing tube and speeds up recovery.
Lyon, RhôneAges 18 years+ - NCT01571986Recruiting
Improving non-invasive breathing support
This study is looking at ways to improve non-invasive ventilation, which is breathing support given without a breathing tube. You may be invited if you’re already receiving this kind of support and you agree to take part.
MilanAges 18–99 - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT06259565RecruitingPhase 3
Breathing mask sedation trial for agitated adults
This trial tests whether adding a sedative called dexmedetomidine to non-invasive ventilation (a breathing mask) helps adults who are agitated or uncomfortable while on the mask. It aims to improve comfort and avoid the need for a breathing tube.
Surrey, British ColumbiaAges 18 years+ - NCT06436638Recruiting
CPAP mask vs. nasal tube for breathing during molar extraction
This trial compares two ways to help you breathe during deep sedation for a molar extraction: a CPAP mask over your nose or a small tube placed in your nostril. The goal is to see which method keeps your oxygen levels more stable.
KayseriAges 18–60 - NCT06339580RecruitingPhase 2
Volume-targeted ventilation for neuromuscular disease
This trial tests a smarter ventilator setting that automatically adjusts pressure to deliver a steady amount of air. It may help people with slowly worsening muscle weakness who already use a nighttime breathing machine.
London, LondonAges 18–80 - NCT06114667Recruiting
Nasal high flow vs. mask for COPD flare-up
This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.
Montpellier, MontepllierAges 18–85 - NCT06021938Recruiting
Virtual Reality for Breathlessness in ALS
This trial tests if using immersive virtual reality can help reduce ongoing shortness of breath in people with ALS who already use a breathing mask (non-invasive ventilation). It may offer a drug-free way to feel more comfortable.
Paris, FranceAges 18 years+ - NCT05785637Recruiting
Home sleep testing after starting noninvasive breathing support
This study checks breathing/sleep measurements done at home for people who recently started a machine that helps them breathe without an endotracheal tube. It may help the team confirm how well home monitoring works after hospital setup of this breathing support.
GarchesAges 18 years+ - NCT05869825Recruiting
Breathing support after extubation in babies after heart surgery
This trial compares two ways of helping babies breathe after their breathing tube is removed following heart surgery. It may help find which support method works better and is safer for the smallest patients.
Atlanta, GeorgiaAges Up to 1 year - NCT05756387Recruiting
Improving nighttime home breathing support for people with COPD
This study tests different ways to improve chronic noninvasive nighttime breathing support at home for people with COPD. It may help make home treatment easier and more effective, using better tools and setup.
GroningenAges Any age - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05163639RecruitingEarly Phase 1
Noninvasive brain and spinal training for spinal cord injury
This early study tests a noninvasive way of training the nervous system to see how it affects “associative plasticity,” or the brain/spinal cord’s ability to change with practice. It may help researchers learn strategies that could improve function for people with spinal cord injury.
New York, New YorkAges 18–80 - NCT04471129Recruiting
Noninvasive breathing support after heart surgery to protect heart function
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
RouenAges 18 years+ - NCT04427826RecruitingPhase 1/Phase 2
Morphine to prevent early NIV failure in COPD flare-ups
This trial studies whether morphine can help people with a COPD flare-up avoid “non-invasive ventilation” (breathing support through a mask) failing early. The goal is to reduce how often people need escalation of care soon after starting NIV.
Grenoble, Isère, Auvergne-Rhône-AlpesAges 18 years+ - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT02464696Recruiting
Noninvasive breathing support to avoid tube breathing in cancer
This trial studies a mask-based breathing treatment (noninvasive ventilation) for people with cancer and serious breathing trouble, to see if it can prevent the need for intubation (putting a breathing tube in). If you qualify, the goal is to help you breathe better without invasive airway support when possible.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for non-invasive ventilation?
- Yes. Clin2 currently lists 62 recruiting non-invasive ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a non-invasive ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a non-invasive ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Non Muscle Invasive Bladder Cancer
- Non Small Cell Lung Cancer
- Non-squamous Non-small Cell Lung Cancer
- Invasive Mechanical Ventilation
- Non-Muscle Invasive Bladder Urothelial Carcinoma
- Non-Muscle Invasive Bladder Neoplasms
- High Risk Non-muscle Invasive Bladder Cancer
- Metastatic Non-squamous Non Small Cell Lung Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.