Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 803 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07422220Recruiting
Walnuts and brain health: a long-term study
This study tests whether eating walnuts every day for a long time can help keep your brain healthy as you age. It is for middle-aged and older adults who carry extra weight around their belly but are otherwise generally healthy.
Maastricht, LimburgAges 45–75 - NCT07225816RecruitingPhase 1
How fasting affects stomach food with GLP-1 drugs
This study looks at how long fasting and temporarily stopping certain diabetes or weight-loss medications (like semaglutide or liraglutide) affects how much food stays in your stomach. It may help understand how these medications work in people who are overweight.
Cypress, CaliforniaAges 18 years+ - NCT07717333Recruiting
Sarcopenia signs after weight loss surgery
This study looks at muscle changes after bariatric (weight loss) surgery. It may help you understand how your muscles are affected and what you can do to stay strong.
Istanbul, KÜÇÜKÇEKMECEAges 18–65 - NCT07272837Recruiting
How semaglutide affects heart and muscle mass
This study looks at how semaglutide (Ozempic or Wegovy) changes heart muscle and body muscle. It may help people with type 2 diabetes or those taking the drug for weight loss understand if their heart is affected.
Edmonton, AlbertaAges 18–80 - NCT03025074Recruiting
Blood sample bank for liver disease research
This study collects blood samples to build a “biobank” (a stored library of samples) for researchers studying liver diseases like hepatitis, fatty liver disease, and liver cancer. It may help future testing and treatments by allowing scientists to study patterns in people with and without liver conditions.
Buffalo, New YorkAges 7 years+ - NCT03132129Recruiting
Heart imaging study in adults with type 2 diabetes
This study looks for early, “silent” changes in heart function in adults with type 2 diabetes, even if you feel okay. It uses heart scans and looks for factors that may help explain why these changes happen.
LeicesterAges 50–75 - NCT03407079RecruitingPhase 2
Study of sucralose’s effects on digestion of drugs
This study tests whether the sugar substitute sucralose changes how your body absorbs and breaks down certain medicines. You’d take sucralose or a placebo for 4 weeks, visit the clinic, and complete required samples and medicine doses during visits.
Bethesda, MarylandAges 18–60 - NCT03455868Recruiting
Bone health check after bariatric surgery in people with diabetes
This study looks at how bariatric (weight-loss) surgery affects bone health in adults with type 2 diabetes. It may help doctors understand who needs extra bone protection after surgery.
Montreal, QuebecAges 18–60 - NCT03866408RecruitingEarly Phase 1
Testing how insulin affects fat breakdown proteins
This early study looks at how insulin changes the body’s fat breakdown and related proteins. You might join if you’re within a certain body-weight range and can safely take the study medication.
Rochester, MinnesotaAges 18–55 - NCT03981640Recruiting
Study how kidney blood flow changes during exercise
This study looks at how blood flow to the kidneys responds when you exercise. Researchers hope the results can help better understand differences in kidney circulation during activity in African American and White adults.
Boston, MassachusettsAges 18–35 - NCT04248127Recruiting
Honey yogurt to improve gut health and mild inflammation
This study tests whether honey-flavored yogurt can improve gut health and “low-grade” inflammation in middle-aged and older women after menopause. You may be asked to follow a yogurt-focused plan and avoid certain foods or supplements to see the effect.
Davis, CaliforniaAges 45–65 - NCT04326192Recruiting
Spinal cord stimulation to reduce stubborn back and leg pain
This trial tests whether spinal cord stimulation (a treatment where a device sends mild signals to the spinal cord) can improve persistent nerve-type back and leg pain. It is mainly for adults who are already planning to try spinal cord stimulation but have not tried it before.
Portland, OregonAges 21–70 - NCT04352244Recruiting
Study of brown fat activity in healthy adults
This study measures how “brown fat” works in the body using planned medical procedures. It looks at healthy adults to understand brown fat activity and what affects it.
Boston, MassachusettsAges 18–75 - NCT04661449Recruiting
Lifestyle program for babies born larger than expected
This trial looks at whether a structured lifestyle program improves health and development outcomes for babies who were born larger than expected (large-for-gestational-age). If you qualify, the study may guide caregiver and family habits to support your child’s early outcomes.
Shanghai, Shanghai MunicipalityAges 1 day–1 month - NCT04805762Recruiting
Coach program for kids with overweight or obesity
This study tests a lifestyle coaching program delivered through “Your COACH Next Door” for children. It may help with weight and healthy habits by providing support to help kids adopt healthier routines.
Maastricht, LimburgAges Up to 18 years - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04940962Recruiting
Study of fat tissue in obesity and type 2 diabetes
This study looks at a specific receptor (CB1) in abdominal fat tissue to understand how it affects fat-related chemicals in the body. Your participation would involve giving consent and having a tissue sample taken during planned internal (visceral) surgery.
DijonAges 18–80 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT05216042Recruiting
Study of genetics and heart/metabolic health in adults
This study looks at how genetic markers (DNA) relate to heart health and “metabolic” health (how your body manages sugar and fat). You may be asked to provide genetic samples and follow study health checks and protocols to help researchers understand who is at higher risk.
Birmingham, AlabamaAges 18 years+ - NCT05235945Recruiting
Exercise program for people waiting for weight-loss surgery
This trial studies whether an exercise program can help people prepare for bariatric (weight-loss) surgery. It aims to see if exercise is safe and beneficial while you’re waiting for your surgery date.
LondonAges 18 years+ - NCT05289310Recruiting
Home low-oxygen nights to study weight and health
This study looks at whether spending 8 hours each night in a low-oxygen tent for 8 weeks affects weight and related health in people with obesity. It also checks safety by monitoring oxygen levels and screening for breathing and heart-related conditions.
Baton Rouge, LouisianaAges 22–65 - NCT05394363Recruiting
Victoria children birth-cohort study with parent/guardian consent
This study follows children born in a specific 2-year window and their parents or guardians over time. It helps researchers understand how children and families change as they grow, which can guide future health supports in Victoria.
Parkville, VictoriaAges 1 day+ - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT05522075Recruiting
Reducing Blood Pressure in Adults Who Binge Drink
This study looks at ways to lower blood pressure in adults ages 50–64 who drink little, moderate, or binge drink. It may help by testing an approach that supports healthier blood pressure in midlife.
Arlington, TexasAges 50–64
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 803 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.