Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05516576Recruiting
Weight-loss procedure plus diabetes care for type 2 diabetes
This trial studies whether an endoscopic (camera-guided) stomach tightening/suturing procedure plus standard diabetes care can improve health in people with type 2 diabetes and mild-to-moderate obesity. It compares this procedure to standard care alone to see which approach works better and is safe.
La TroncheAges 18–65 - NCT07302802Recruiting
Semaglutide for weight loss in teens with genetic obesity
This trial studies whether semaglutide (a once-weekly injection) helps adolescents with a specific genetic form of obesity lose weight. It is for teens who are already being prescribed semaglutide as part of their regular care.
ParisAges 12–21 - NCT05977348Recruiting
Preschool nutrition lessons to help prevent future obesity
This trial tests a program to improve food knowledge and healthy eating habits in preschool children. It may help families by teaching practical ways to choose and handle foods earlier to reduce later obesity risk.
University Park, PennsylvaniaAges 3–6 - NCT07293325Recruiting
Semaglutide and Tirzepatide for slowing aging in adults with obesity
This trial tests if two newer weight-loss medications, semaglutide and tirzepatide, can help slow the aging process in adults with obesity. It compares the drugs to each other and to a placebo to see which might offer anti-aging benefits beyond weight loss.
HangzhouAges 18–75 - NCT07296900Recruiting
International genetic obesity registry study
This study is creating a worldwide registry for people with genetic forms of obesity. It aims to learn more about these conditions and may help develop better treatments in the future.
UlmAges Any age - NCT07291232RecruitingPhase 1
Study of an injected drug for adults with obesity
This study tests an injected medication called ABBV-295 for adults with obesity. The goal is to see how safe it is and how the body processes it. You may join if you have a BMI between 30 and 45 and are generally healthy, and you haven't been on other weight loss treatments recently.
Anaheim, CaliforniaAges 18–65 - NCT06254261RecruitingPhase 2
RAY1225 for weight loss in obesity
This study tests an investigational medication called RAY1225 in people with obesity. It's given as an injection and may help with weight loss by targeting hormones that control appetite.
Beijingcun, HebeiAges 18–70 - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT06890169Recruiting
One-stop telehealth program for weight and diabetes
This trial tests a telehealth program that helps people lose weight and manage type 2 diabetes and fatty liver disease at the same time. It's a one-stop remote clinic that combines medical advice, nutrition, and lifestyle support.
SingaporeAges 21–70 - NCT05966727Recruiting
Cholestyramine to lower stored pollutants in obese women
This study tests whether cholestyramine can lower blood levels of certain stored environmental pollutants (“POPs”) in women preparing for weight-loss surgery. If it works, it may help reduce pollutant levels that can build up in the body over time.
Nice, Alpes-MritimesAges 18–45 - NCT05759637Recruiting
Tests treatments for diabetes, weight, and high cortisol levels
This trial studies people who have type 2 diabetes and excess body weight, looking at how high cortisol (a stress hormone) may be involved. If you qualify, you may get a study treatment designed to improve diabetes and weight-related health by targeting cortisol-related pathways.
MilanAges 18–75 - NCT06847373Recruiting
Vitamin D for teens with obesity
This study is testing whether vitamin D supplements can help teens with obesity. It is open to participants aged 10 to 18 who live in Mexico City and have obesity based on their BMI.
MéxicoAges 10–18 - NCT07254065Recruiting
Preventing obesity early with telehealth support
This study tests a telehealth program to help prevent obesity in pregnant women. It offers support and education through video calls to promote healthy habits.
New Hyde Park, New YorkAges 18 years+ - NCT07247084RecruitingPhase 4
Tirzepatide for weight loss in adults with obesity
This trial tests if tirzepatide is more effective than standard obesity treatments for adults who have a BMI between 30 and 35 and one weight-related health condition, but do not have diabetes. The goal is to help you lose weight.
AltrinchamAges 18 years+ - NCT02902198Recruiting
Study of taste changes before and after bariatric surgery
This study looks at how your sense of taste works before and after bariatric weight-loss surgery. It may help doctors understand why eating patterns change after surgery.
BaselAges 18–55 - NCT07236788Recruiting
Iron infusion to prevent anemia and improve life in obese patients
This trial tests whether giving an intravenous iron supplement (ferric derisomaltose) can help prevent anemia and improve quality of life in obese patients who have low iron stores. It aims to see if this treatment can boost energy and reduce fatigue.
BeijingAges 18–65 - NCT07230808Recruiting
Obesity prevention program for parents in home visiting
This trial offers a digital program to help parents prevent childhood obesity. It's designed for families already in a home visiting program and aims to support healthy growth in babies born healthy and on time.
Gainesville, FloridaAges 16–65 - NCT07228741RecruitingPhase 2
Exercise and medicine for heart health in ALL survivors with obesity
This trial tests if combining resistance exercise with the weight-loss medication tirzepatide can improve heart and metabolic health in survivors of childhood acute lymphoblastic leukemia (ALL) who are now adults and have obesity or overweight with related health issues. You may benefit if you finished treatment at least 2 years ago and meet weight and health criteria.
Memphis, TennesseeAges 18 years+ - NCT07229508Recruiting
Weight gain study for children from BIPOC or low-income families
This study looks at how children gain weight over time, especially in families of color or with low income. It helps understand why some kids struggle with weight and what can be done to help.
Buffalo, New YorkAges 8–11 - NCT06710340Recruiting
Study of nuts in women with obesity and diabetes
This study looks at how eating nuts affects blood sugar and other health measures in women with obesity and type 2 diabetes. It may help understand if nuts can be a helpful part of managing diabetes.
Botucatu, São PauloAges 18 years+ - NCT07220772RecruitingPhase 3
A drug for severe obesity caused by leptin gene mutations
This trial tests a new drug called mibavademab for people with severe obesity caused by changes in the leptin (LEP) gene. It aims to see if the drug can help with weight loss in children, teens, and adults who have this rare genetic condition.
UlmAges 2 years+ - NCT07213466RecruitingPhase 4
Personalized weight-loss medication for bipolar disorder
This study wants to see if a personalized approach with FDA-approved weight-loss medications can help people with bipolar disorder who are overweight or have obesity, while staying on their mood stabilizer treatment. It might be a good fit if you have bipolar disorder and struggle with your weight.
Rochester, MinnesotaAges 18–65 - NCT07216820Recruiting
Nerve blocks for shoulder surgery in obesity
This study compares two types of nerve blocks for shoulder surgery in people with obesity. It tests whether a block that spares the phrenic nerve (which helps you breathe) can keep your breathing strength stronger after surgery.
Chapel Hill, North CarolinaAges 18 years+ - NCT07218445RecruitingPhase 4
Tirzepatide for hot flashes in post-menopausal women with obesity
This study tests whether tirzepatide, a weekly injection, can reduce bothersome hot flashes and slow biological aging in post-menopausal women with obesity. It also includes a personalized diet and exercise plan.
Jacksonville, FloridaAges 46–60
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,474 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.