Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 739 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06489483Recruiting
Parkinson's and action regulation study in Dallas
This study looks at how people with Parkinson's disease regulate their actions. It will test your behavior during 'on' periods (when medication is working well) to understand decision-making and movement control.
Dallas, TexasAges 18–80 - NCT06498349Recruiting
DBS for Parkinson's impulse control problems
This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.
CologneAges 18–70 - NCT06542991Recruiting
Transcranial magnetic stimulation for Parkinson's disease
This study tests whether repetitive transcranial magnetic stimulation (rTMS) can help people with Parkinson's disease. You will receive rTMS and be evaluated for changes in movement and thinking.
Hefei, AnhuiAges 40 years+ - NCT06553625Recruiting
RF ablation study for pain or CNS conditions
This study observes how well a Boston Scientific radiofrequency (RF) system works for treating pain or central nervous system (CNS) conditions. It helps researchers understand real-world benefits for patients scheduled for this procedure.
CologneAges Any age - NCT06570824Recruiting
Can repetitive TMS help with levodopa-induced dyskinesia?
This study tests whether a non-invasive brain stimulation technique called repetitive TMS can reduce the involuntary movements (dyskinesia) that some people with Parkinson's disease experience as a side effect of their levodopa medication. If you have Parkinson's and bothersome dyskinesia when your medication is working, this trial may be an option.
HvidovreAges 18–80 - NCT06608875Recruiting
Personalized stimulation to improve walking and balance
This trial tests a way to help people with Parkinson's disease improve their walking and balance by using personalized stimulation. If you have trouble with walking or balance and are already planning rehab at cereneo, you might be able to join.
Zurich, Canton of ZurichAges 18 years+ - NCT06617884Recruiting
Home balance training for movement disorders
This study tests a home-based walking and balance training program for people with cerebellar ataxia or Parkinson's disease. The training is done at home, so you don't need to travel. The goal is to see if this simple exercise program can improve your walking and balance.
Düsseldorf, North Rhine-WestphaliaAges 18–75 - NCT06683365RecruitingPhase 1
Nerve graft trial for Parkinson's or MSA
This trial tests whether grafting a piece of your own leg nerve into a specific part of the brain can improve symptoms of Parkinson's disease or multiple system atrophy (MSA). It aims to help people whose movement problems are moderate but not too severe.
Lexington, KentuckyAges 40–75 - NCT06690931Recruiting
Brain training with electrical stimulation and virtual reality for Parkinson's
This study tests a new type of therapy that combines brain training (neurofeedback), mild electrical stimulation to help with movement, and virtual reality exercises. It aims to improve walking and movement for people with Parkinson's disease.
Schiedlberg, Upper AustriaAges 40–80 - NCT06778135Recruiting
Brain cell study in Parkinson's DBS surgery
This trial studies how brain cells in a specific area (the prefrontal cortex) affect thinking and planning in people with Parkinson's disease who are getting deep brain stimulation (DBS) surgery. The goal is to learn more about brain function to improve future treatments.
Aurora, ColoradoAges 45–85 - NCT06799923Recruiting
MRI-guided laser therapy for hard-to-treat tremor
This trial tests a new, less invasive treatment for severe tremor that hasn't responded to medication. It uses a laser guided by MRI to carefully target and treat the brain area causing tremor, as an alternative to traditional brain surgery.
SalouëlAges 18 years+ - NCT06835595Recruiting
Brain signals as markers of thinking changes in Parkinson's
This study uses a safe, noninvasive brain stimulation method (transcranial magnetic stimulation, or TMS) to look at brain signals related to thinking and memory in people with Parkinson's disease. The goal is to find a better way to measure cognitive changes over time.
Trieste, Friuli Venezia GiuliaAges 18 years+ - NCT06875765Recruiting
Long-term brain imaging study for Parkinson's patients
This study uses brain scans to look at nerve endings in people with Parkinson's disease over time. It may help researchers understand how the disease progresses.
LeuvenAges 30 years+ - NCT06883266Recruiting
Brain stimulation for movement and fatigue in Parkinson's
This study tests whether a gentle brain stimulation technique called tDCS (transcranial direct current stimulation) can help improve movement and reduce fatigue in people with Parkinson's disease. It's an option for those who are not using deep brain stimulation and don't have certain other health conditions.
Fargo, North DakotaAges Any age - NCT06906276Recruiting
Brain activity during walking in atypical Parkinson's
This study looks at brain activity while walking in people with atypical Parkinsonian syndromes like PSP or MSA. It may help understand how these conditions affect walking and balance.
Solna, SolnaAges Any age - NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+ - NCT06942533Recruiting
Using SpiroGym app to help Parkinson's breathing
This trial tests whether using a mobile app that gives visual feedback while doing breathing exercises can improve symptoms in people with Parkinson's disease. It may help you if you are on stable medication.
PragueAges 40–80 - NCT06960096Recruiting
Cognitive decline after deep brain stimulation: an MRI study
This study uses MRI scans to see how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease. It may help researchers understand why some people experience cognitive changes after DBS surgery.
Charleston, South CarolinaAges 18 years+ - NCT06962930Recruiting
Online coaching to help people with Parkinson's stay active
This study tests whether online coaching sessions can help people with Parkinson's disease in Qatar become more physically active. You'll receive coaching from home, so it's convenient and safe.
DohaAges 18 years+ - NCT06994728Recruiting
How DBS affects vision and freezing of gait in Parkinson's
This trial looks at how deep brain stimulation (DBS) affects the way you see and move, and how that relates to freezing of gait (when your feet suddenly feel stuck). If you have Parkinson's disease, already have a DBS device, and experience freezing, this study may help researchers understand your symptoms better.
Charleston, South CarolinaAges 18 years+ - NCT06997484RecruitingPhase 1
Testing safety of HL-400 in healthy adults
This study tests a new drug called HL-400 for the first time in people. It checks how safe the drug is and how the body handles it, to see if it could be developed for future patients.
Baltimore, MarylandAges 18–65 - NCT06998303Recruiting
Brain imaging study for Parkinson's DBS patients
This study uses MRI scans to look at brain activity in people with Parkinson's disease who have a Medtronic Percept DBS device. The goal is to better understand how deep brain stimulation works.
Minneapolis, MinnesotaAges 21 years+ - NCT07038486Recruiting
Testing a digital tool for Parkinson's symptoms
This study tests a digital tool (NMS Assist) to help people with Parkinson's and their caregivers track and manage non-motor symptoms like mood, sleep, and thinking changes. Participation takes place from home using a smartphone or tablet.
Newcastle upon Tyne, Tyne and WearAges 18 years+ - NCT07044973Recruiting
Focused ultrasound for Parkinson's disease tremor
This trial uses focused ultrasound to treat tremor and movement problems in Parkinson's disease. It targets a specific brain area without surgery, and may help if your symptoms are worse on one side and not fully controlled by medication.
Beijing, Beijing MunicipalityAges 22 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 739 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.