Clinical trials
Persistant Atrial Fibrillation clinical trials
Below are recruiting persistant atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 213 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07267949RecruitingPhase 2
Study of AP31969 for atrial fibrillation rhythm control
This study tests a new medication, AP31969, to control heart rhythm in people with atrial fibrillation. It compares the drug to a placebo to see if it can reduce how often AF episodes happen over time.
Plovdiv, PDAges 18 years+ - NCT05903170Recruiting
Shock energy study for heart rhythm conversion in atrial fibrillation
This trial tests whether using a specific “shock energy” during electrical cardioversion works safely and effectively for people with persistent atrial fibrillation. You might be eligible if your cardioversion is planned (not an emergency) and your doctors determine you can safely take blood thinners.
Wellington, Wellington RegionAges 18 years+ - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT07181590Recruiting
Balloon-based ablation for atrial fibrillation: post-approval study
This trial tests a balloon catheter that uses pulsed field energy to treat atrial fibrillation (AF) in people who have tried medication without success. It aims to see how well it works in real-world use.
LinzAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07156877Recruiting
Balloon Catheter Ablation for Atrial Fibrillation
This study tests a new balloon catheter that uses pulsed electric fields to isolate the veins that carry blood from your lungs to your heart. It may be a treatment option for people with atrial fibrillation who are scheduled for an ablation procedure.
BrugesAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT07122336Recruiting
A better way to treat persistent atrial fibrillation
This trial tests a new method to treat persistent atrial fibrillation (a long-lasting irregular heartbeat) to see if it helps patients who haven't been helped by medication. It focuses on cleaning up the back wall of the heart to restore a normal rhythm.
ShanghaiAges 18–80 - NCT07106970Recruiting
Comparing two ablation approaches for persistent atrial fibrillation
This trial tests whether adding extra ablation lines to the standard pulmonary vein isolation procedure is more effective for people with persistent atrial fibrillation that hasn't been helped by medications. The goal is to improve symptoms like palpitations, fatigue, and shortness of breath.
BeijingAges 18–80 - NCT07100483Enrolling by invitation
Comparing surgery methods for atrial fibrillation
This trial studies different surgical techniques for treating atrial fibrillation during heart surgery. It may help people with a history of AFib who are already scheduled for open-heart surgery.
Grand Rapids, MichiganAges 18–85 - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT02741349Recruiting
Checking stroke and bleeding risks in atrial fibrillation
This study looks at how to better predict both stroke risk and bleeding risk in people with atrial fibrillation. It may help doctors choose safer blood-thinner treatment and follow-up plans.
ParisAges 18 years+ - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT07064616Recruiting
Pulsed field vs. cryoballoon ablation for persistent atrial fibrillation
This trial compares two techniques—pulsed field ablation and cryoballoon ablation—to treat persistent atrial fibrillation (a type of irregular heartbeat that lasts less than a year). The goal is to see which method works better and is safer for patients.
Sagamihara, KanagawaAges 18–85 - NCT05890664RecruitingPhase 3
Colchicine after shock treatment to stop atrial fibrillation
This trial tests whether colchicine given after cardioversion (a procedure that restores normal rhythm) helps keep the heart in normal rhythm afterward. It may help some people have fewer early returns of atrial fibrillation.
Bruderholz, Basel-LandschaftAges 18 years+ - NCT07036965Recruiting
Comparing two types of ablation catheters for atrial fibrillation
This trial tests two different catheters that use pulsed field energy to treat atrial fibrillation (a heart rhythm problem). It aims to find which one works better for people who need blood thinners but have a high risk of bleeding.
HangzhouAges 118 years+ - NCT06988202Enrolling by invitation
Comparing repeat ablation methods for atrial fibrillation
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
Rochester, New YorkAges 18 years+ - NCT06985901Recruiting
Pulsed-field ablation for persistent atrial fibrillation
This trial tests a new type of ablation (pulsed-field) to treat persistent atrial fibrillation (AFib) that lasts more than 7 days. You may qualify if you have symptoms and haven't had other heart ablation procedures except for one specific type.
NiceAges 18 years+ - NCT05266144Recruiting
Catheter ablation for non-valvular atrial fibrillation
This trial studies catheter ablation, a procedure that targets heart rhythm triggers, for people with atrial fibrillation (an irregular heartbeat). It may help improve rhythm control, but you must meet specific heart and testing requirements and avoid certain conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT06973031Recruiting
Testing a new system for treating atrial fibrillation
This trial tests a new device that uses pulsed electric fields to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to see if this approach is safe and effective for people with AF that comes and goes or lasts for a short time.
KaiserslauternAges 18–80 - NCT06960252Recruiting
Cycle length mapping for long-term atrial fibrillation
This study tests a new mapping technique to find chaotic electrical signals in the heart during persistent atrial fibrillation. It may help doctors better target treatment for people whose atrial fibrillation does not stop with medication.
Taipei, Outside USAges 20 years+ - NCT06959121Recruiting
Treating AFib during open-heart surgery with a new device
This trial tests a new device used during open-heart surgery to treat atrial fibrillation (AFib) by delivering tiny, fast electrical pulses to the heart tissue. It is for people who are already having heart surgery and want to also treat their AFib at the same time.
St. Helena, CaliforniaAges 18–85
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Common questions
- Are there clinical trials for persistant atrial fibrillation?
- Yes. Clin2 currently lists 213 recruiting persistant atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a persistant atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a persistant atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.