Clinical trials
Persistant Atrial Fibrillation clinical trials
Below are recruiting persistant atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06988202Enrolling by invitation
Comparing repeat ablation methods for atrial fibrillation
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
Rochester, New YorkAges 18 years+ - NCT04404465Enrolling by invitation
Test blood/heart signals to understand atrial fibrillation changes
This study looks at early changes in the heart related to atrial fibrillation (AF) using health data and biomarkers. It aims to find better ways to predict or understand AF, especially around procedures like ablation or cardioversion.
San Francisco, CaliforniaAges 18 years+ - NCT04148625Enrolling by invitation
Sub-xiphoid hybrid maze for persistent atrial fibrillation after failed ablation
This trial studies a hybrid heart procedure to treat persistent atrial fibrillation in people whose previous catheter ablation did not work. It aims to improve heart rhythm and reduce ongoing symptoms by using a planned combination of techniques and careful follow-up.
Ages 18–80 - NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT05427435Recruiting
Testing alcohol treatment of a heart vein during atrial fibrillation ablation
This study tests whether applying a small amount of alcohol to a specific heart vein (“vein of Marshall”) is safe and feasible during a standard atrial fibrillation (AF) ablation. It may help improve AF treatment, but the goal here is mainly to see if the approach can be done safely in the right patients.
PessacAges 18 years+ - NCT05996159Recruiting
Using very high power for short duration to treat atrial fibrillation
This study tests a new way to perform a common procedure (pulmonary vein isolation) for people with paroxysmal atrial fibrillation. Instead of using the standard amount of energy for a longer time, this method uses a very high amount of energy for a very short time. This might make the procedure faster and just as safe.
SeoulAges 19 years+ - NCT06096246Recruiting
Comparing treatments for persistent atrial fibrillation
This study compares two treatments for persistent atrial fibrillation (AF) that lasts more than 7 days but less than 2 years: electrical cardioversion (a shock to reset your heart rhythm) versus catheter ablation (using radio waves to fix the heart's electrical pathways). It aims to find which option works better for patients like you.
LondonAges 18–85 - NCT06184633RecruitingPhase 4
Weight control in atrial fibrillation study
This study tests if a weight management program helps people with a new type of irregular heartbeat (atrial fibrillation) and obesity. It aims to see if losing weight can improve heart rhythm and reduce the need for further treatment.
Arnhem, GelderlandAges 18 years+ - NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Birmingham, AlabamaAges 18 years+ - NCT06455098Recruiting
Pulsed field ablation for paroxysmal atrial fibrillation
This study tests a new procedure called pulsed field ablation using a special catheter to treat paroxysmal atrial fibrillation (AF), a type of heart rhythm problem that comes and goes. It may be an option for people whose AF hasn't been controlled well with medication.
Phoenix, ArizonaAges 18–80 - NCT06995391Recruiting
Alcohol reduction app for atrial fibrillation
This trial tests if a smartphone app can help people with atrial fibrillation reduce or stop drinking alcohol. The goal is to see if cutting down on alcohol makes AF symptoms less severe or occur less often.
San Francisco, CaliforniaAges 21 years+ - NCT07047235Recruiting
Targeted ablation for persistent atrial fibrillation
This trial is testing a specific approach to catheter ablation for people with persistent atrial fibrillation. It aims to improve how abnormal heart tissue is targeted to help restore a normal rhythm.
LondonAges 18 years+ - NCT07130773Recruiting
Comparing two catheter types for atrial fibrillation ablation
This trial compares two types of special catheters (thin tubes) used during a procedure called ablation to treat atrial fibrillation (irregular heartbeat). It aims to see which catheter works better during the procedure, and may help improve future treatments for people with heart rhythm problems.
Lugano, Canton TicinoAges 18 years+ - NCT07358611Recruiting
Heart mapping-guided ablation for persistent atrial fibrillation
This trial tests whether using a special heart-mapping device during ablation (a procedure to fix irregular heartbeats) can improve outcomes for people with persistent atrial fibrillation and an enlarged left heart chamber.
BarcelonaAges 18 years+ - NCT07630857Recruiting
Heart Mapping to Personalize Atrial Fibrillation Treatment
This trial tests a new way to map the heart's electrical signals to help doctors better target and treat atrial fibrillation (an irregular heartbeat). If you're having a procedure to treat AF, this study may help improve the success of your treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT06200311Recruiting
Atrial fibrillation ablation to prevent heart damage in women and men
This trial tests whether a procedure called AF ablation (which treats irregular heartbeats) can stop further damage to the heart muscle caused by atrial fibrillation. It may help people with both atrial fibrillation and early signs of heart muscle weakening.
GroningenAges 65–80 - NCT06212674RecruitingPhase 4
Stroke prevention: combined heart procedure for atrial fibrillation
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
Katowice, Upper SilesiaAges 18–75 - NCT04685317Recruiting
Sentinel brain-protection device during atrial fibrillation ablation
This trial tests whether a specialized “brain protection” device can improve safety during atrial fibrillation (AF) catheter ablation. It may help reduce the risk of stroke or related complications while treating AF.
Rochester, MinnesotaAges 18 years+ - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+ - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Little Rock, ArkansasAges 18 years+ - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT07139301Recruiting
Timing of blood thinners after stroke clot removal in atrial fibrillation
This study aims to find the best time to start blood thinners after emergency clot removal in people with atrial fibrillation who had a stroke. It may help reduce the risk of another stroke or bleeding.
Ma’anshan, AnhuiAges 18 years+ - NCT06401616RecruitingPhase 4
Stopping blood thinners after heart surgery for atrial fibrillation
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
Copenhagen, Capital RegionAges 18 years+ - NCT06929897Enrolling by invitation
Comparing Two Ablation Methods for Persistent Atrial Fibrillation
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
SeoulAges 20–80
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Common questions
- Are there clinical trials for persistant atrial fibrillation?
- Yes. Clin2 currently lists 216 recruiting persistant atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a persistant atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a persistant atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.