Clinical trials
Persistent Atrial Fibrillation clinical trials
Below are recruiting persistent atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 213 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06556667Recruiting
Comparing two cardioversion methods for persistent AFib
This trial compares two ways of doing cardioversion (a procedure to restore normal heart rhythm) for people with persistent atrial fibrillation. It aims to see if one approach leads to a better recovery and fewer complications.
Ottawa, OntarioAges 18 years+ - NCT06589700Recruiting
Atrial Fibrillation and Stroke Risk Study
This study looks at the link between the type of atrial fibrillation (an irregular heartbeat that comes and goes) and the risk of having another stroke. It involves people who have had a recent ischemic stroke and have a certain type of AF.
London, OntarioAges 18 years+ - NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT07428564Recruiting
VARIPULSE catheter and TRUPULSE generator for persistent atrial fibrillation
This study tests a new catheter and generator system to treat persistent atrial fibrillation (an irregular heartbeat that lasts more than a week). It may help people whose symptoms haven't been controlled by medication and who need a procedure called ablation to fix the heart's electrical signals.
AalstAges 18–75 - NCT06844227Recruiting
Virtual Visit to Manage Blood Thinners Around Surgery
This study looks at whether a virtual visit can safely manage your blood thinners around the time of a planned surgery. You would stop your medication before the procedure and restart it after, but all instructions and check-ins happen remotely (phone or video).
Evanston, IllinoisAges 18–100 - NCT06935591Recruiting
AI-guided ablation for hard-to-treat atrial fibrillation
This trial uses an artificial intelligence system (vMap) to find and target abnormal electrical signals outside the pulmonary veins that may be driving atrial fibrillation (AF). The goal is to improve ablation results for people with persistent or recurrent AF.
Jonesboro, ArkansasAges 22 years+ - NCT06957366Recruiting
Managing Blood Thinners Before High-Risk Surgery
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Hartford, ConnecticutAges 18 years+ - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07024927Recruiting
Heart rhythm disorder registry
This study observes people with atrial fibrillation or ventricular tachycardia who are having their first catheter ablation procedure. The goal is to collect information to improve future treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07118046Recruiting
X-ray vs. 3D mapping for balloon AFib ablation
This study compares two ways to guide a balloon-based ablation procedure for atrial fibrillation: using only X-ray (fluoroscopy) versus using a 3D mapping system. The goal is to see if one method is safer or more effective.
Madrid, MadridAges 18 years+ - NCT07122947Recruiting
Apple Watch to detect AFib after heart surgery
This study tests if an Apple Watch can help detect when atrial fibrillation (an irregular heartbeat) comes back after heart surgery. You'll wear an Apple Watch and a small skin patch (Zio Patch) to track your heart rhythm.
St Louis, MissouriAges 22 years+ - NCT07129564Recruiting
Stepwise treatment for persistent atrial fibrillation
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
ChongqingAges 18–70 - NCT07250529Recruiting
Comparing two pacemaker pacing methods for heart block
This study compares two types of pacemaker pacing methods in people with heart block and normal heart pumping function. It looks at how often short bursts of fast heart rhythm occur in the upper heart chambers, which may help improve long-term heart health.
PátraiAges 18 years+ - NCT07389434Recruiting
Testing reused catheters for atrial fibrillation treatment
This trial tests whether reusing special catheters to treat atrial fibrillation is safe, effective, and better for costs and the environment. It may help people with atrial fibrillation who need a procedure called pulmonary vein isolation.
ZagrebAges 18 years+ - NCT07421076Recruiting
Grid mapping study for atrial fibrillation ablation
This trial tests a new mapping tool to help doctors find and treat the source of atrial fibrillation (AF) during a standard ablation procedure. It may offer a more precise way to guide treatment for people with AF that comes and goes.
Jinan, ShandongAges 18 years+ - NCT07439016Recruiting
LA function after pulse field ablation for paroxysmal AF
This trial tests how pulse field ablation (a treatment that uses short electrical pulses to correct irregular heartbeats) affects the left atrium's function in people with paroxysmal atrial fibrillation (AFib that comes and goes). It may help if you have paroxysmal AFib and are in normal rhythm at the start of the procedure.
PragueAges 18 years+ - NCT07462910Recruiting
Checking diaphragm nerve function after pulsed field ablation
This study looks at how a new type of catheter ablation (pulsed field ablation) for atrial fibrillation affects the phrenic nerve, which controls the diaphragm. Researchers will use X-rays to see if the treatment causes any temporary diaphragm problems.
MontrealAges 18 years+ - NCT07574697Recruiting
Genetic Study of Atrial Fibrillation and Heart Function Recovery
This study looks at genetic factors in people with atrial fibrillation (an irregular heartbeat) and weak heart function to understand why some people's hearts recover after treatment and others don't. Researchers will collect blood samples and medical information to identify genetic patterns.
LondonAges 18 years+ - NCT07618741Recruiting
Improving AF Ablation Outcomes in Patients with Obesity
This study tests whether special care strategies can help obese patients have better results after a catheter ablation procedure for atrial fibrillation (a heart rhythm problem). Catheter ablation uses heat or cold to fix the irregular heartbeats.
TaipeiAges 20 years+ - NCT07154303Enrolling by invitation
Testing smartphones to detect irregular heart rhythm
This trial tests if smartphones and their accessories can detect a specific type of irregular heart rhythm called atrial fibrillation. If you have a form of atrial fibrillation or a normal heart rhythm, you may help see how well these devices work.
Hong KongAges 22 years+ - NCT06789588Enrolling by invitationPhase 3
Better warfarin therapy for atrial fibrillation
This study tests a better way to manage warfarin (a blood thinner) for people with atrial fibrillation (an irregular heartbeat). The goal is to improve treatment and help prevent stroke.
Recife, PernambucoAges 18 years+
Hear when a new Persistent Atrial Fibrillation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for persistent atrial fibrillation?
- Yes. Clin2 currently lists 213 recruiting persistent atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a persistent atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a persistent atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.