Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06917404RecruitingPhase 3
Knee osteoarthritis pain study: comparing a new injection to placebo
This phase 3 study tests whether a medicine called pentosan polysulfate sodium (PPS), given as a shot under the skin, reduces pain in people with knee osteoarthritis. It compares PPS to a placebo (a shot with no active medicine) to see if it is safe and effective.
Peoria, ArizonaAges 18 years+ - NCT06928272RecruitingPhase 3
Long COVID drug study for adults 18 to 65
This study tests whether a commonly used drug (repurposed) can help improve Long COVID symptoms like fatigue, breathing problems, or brain fog. It is for adults 18 to 65 who had COVID-19 in the past 4 years and still have symptoms after 3 months.
San Diego, CaliforniaAges 18–65 - NCT06929364Recruiting
Probiotics for endometriosis – a crossover trial
This study tests whether taking a probiotic supplement can help with endometriosis symptoms. It's for women 35 or younger with moderate to severe endometriosis, and involves a crossover design where everyone gets both the probiotic and a placebo at different times.
ZagrebAges Up to 35 years - NCT06945406RecruitingPhase 1
Study of an investigational drug for diabetes
This trial tests a new medicine, LY4057996, in people with type 1 or type 2 diabetes and in healthy volunteers. It aims to see if the drug is safe and how it works in the body.
NeussAges 18 years+ - NCT06947928RecruitingPhase 2/Phase 3
Vaccine plus immunotherapy for Merkel cell cancer
This trial tests an experimental vaccine (IFx-Hu2.0) followed by the immunotherapy drug pembrolizumab in people with advanced Merkel cell carcinoma who have not been treated with checkpoint inhibitors before. The goal is to see if this combination helps shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06953869RecruitingPhase 3
Testing a sleep medicine for children with insomnia
This study tests if the drug tasimelteon helps children with insomnia sleep better compared to a placebo (a pill with no medicine). It is for children aged 2 to 17 who have been diagnosed with insomnia that is not caused by another medicine.
Dothan, AlabamaAges 2–17 - NCT06955728RecruitingPhase 3
RSV vaccine in pregnancy to protect babies
This study tests an approved RSV vaccine given to pregnant women. The goal is to see if it safely protects their babies from severe RSV lung infections during the first months of life.
Kintampo, Bono EastAges 14–55 - NCT06956482RecruitingPhase 3
Longer steroids or N-acetylcysteine for severe alcoholic hepatitis
This trial tests whether giving corticosteroids for a longer time, or adding a medicine called N-acetylcysteine, can help people with severe alcoholic hepatitis. It is for patients who have been drinking heavily and recently developed jaundice.
LilleAges 18–75 - NCT06960369RecruitingPhase 1
Brain stimulation and probiotics for diarrhea-predominant IBS
This trial tests whether combining a type of brain stimulation (repetitive transcranial magnetic stimulation) with a probiotic tablet can help people with diarrhea-predominant irritable bowel syndrome. It aims to improve symptoms by targeting both the brain and the gut.
Suzhou, JiangsuAges 18–70 - NCT06966245RecruitingPhase 3
Oil for severe breast pain in premenopausal women
This trial tests whether an oil applied to the breast can reduce severe breast pain in premenopausal women. If you have had breast pain for at least six months and it is not caused by the chest wall, this study may be a good fit.
GuangzhouAges 18–60 - NCT06979375RecruitingPhase 2
Study of CDR132L for heart failure with reduced pumping ability and thickened heart muscle
This trial tests a new medicine called CDR132L to see if it improves heart structure and function in people with heart failure who have a thickened heart muscle and reduced pumping ability. Participants will be randomly assigned to receive either the study drug or a placebo.
Concord, New South WalesAges 40–84 - NCT06981936RecruitingPhase 4
Do vitamins help prevent deficiencies while on weight-loss injections?
This trial tests if a daily multivitamin and mineral tablet can prevent nutrient shortages in people taking GLP-1 medicines (like Wegovy or Saxenda) for weight loss. You would take either the vitamin tablet or a placebo (a tablet with no active ingredients) for a year, to see which group has better nutrient levels.
AlexandriaAges 18–65 - NCT06982183RecruitingPhase 4
Propranolol and hydrocortisone effects on military performance
This trial studies how two medications—propranolol (a beta blocker often used for anxiety) and hydrocortisone (a steroid)—affect performance on military tasks. It aims to understand if these drugs help or hinder how soldiers perform under stress.
Silver Spring, MarylandAges 18–40 - NCT06982963RecruitingPhase 2
Study of an experimental drug for celiac disease
This study tests an experimental medication for adults with celiac disease to see if it can protect against gluten exposure. You will need to follow a gluten-free diet and undergo a short, planned gluten challenge.
MelbourneAges 18–70 - NCT06983054RecruitingPhase 4
Salt, kidneys, and ertugliflozin in type 2 diabetes
This study tests if changing how much salt you eat affects how the drug ertugliflozin works in people with type 2 diabetes. You would take either the drug or a placebo (a dummy pill) for a short time while following a low- or high-salt diet, to see how your kidneys and blood vessels respond.
Denver, ColoradoAges 18–85 - NCT06992427RecruitingPhase 3
Gabapentin to prevent opioid use for mouth pain during cancer treatment
This trial tests if taking gabapentin during chemoradiation for head and neck cancer can reduce the need for strong painkillers like opioids. It may help manage mouth pain caused by treatment.
Gilbert, ArizonaAges 18 years+ - NCT06998108RecruitingPhase 3
A new drug with fulvestrant for HR+/HER2- advanced breast cancer
This trial tests a new investigational drug called BEBT-209 combined with fulvestrant (a hormone therapy) versus placebo with fulvestrant for people with a type of breast cancer that is hormone receptor-positive and HER2-negative. It is for those whose cancer has worsened after previous hormone therapy and has spread locally or to other parts of the body.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07010107RecruitingPhase 3
Testing anaprazole for moderate to severe reflux esophagitis
This trial tests a new medicine called anaprazole for people with moderate to severe reflux esophagitis (chronic heartburn and damage to the food pipe). It compares anaprazole to a standard treatment to see which works better and is safer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07010432RecruitingPhase 1
Trial of Cagrilintide for bone health in postmenopausal women
This trial tests whether cagrilintide, a medicine similar to a natural hormone called amylin, can affect bone health. It is for postmenopausal women with obesity who do not have bone disease or other conditions affecting bone metabolism.
HerlevAges 50–70 - NCT07011511RecruitingPhase 1
Testing a new malaria drug in healthy volunteers
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
NottinghamAges 18–60 - NCT07016750RecruitingPhase 3
Study of KB803 eye drops for eye scrapes in DEB
This study tests an experimental eye drop (KB803) to see if it can reduce painful scrapes on the surface of the eye in people with dystrophic epidermolysis bullosa. You would be randomly assigned to receive either the study drops or a placebo (an inactive drop) for several months.
Rancho Santa Margarita, CaliforniaAges 6 months+ - NCT07033026RecruitingPhase 2
Study of NGM120 for weight loss in colorectal cancer
This study tests an experimental drug called NGM120 for people with colorectal cancer who are losing weight (a condition called cancer cachexia). It is a placebo-controlled trial, meaning some participants will receive the drug and some will receive a placebo, to see if the drug helps stop or reverse this weight loss.
Los Angeles, CaliforniaAges 18 years+ - NCT07041489Recruiting
Supplement and serum for hair growth in women with thinning hair
This trial tests whether a combination of a dietary supplement and a topical serum can help women with thinning hair grow thicker, fuller hair. It's designed for women who have noticed mild to moderate hair thinning and want a non-invasive approach.
Birmingham, AlabamaAges 28–65 - NCT07044297RecruitingPhase 3
A study of a new long-acting shot to prevent HIV
This study tests an investigational long-acting shot (MK-8527) to prevent HIV. It is for HIV-negative people who are at higher risk through anal sex without condoms, and who have not used other long-acting HIV prevention before.
Birmingham, AlabamaAges 16 years+
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,198 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.