Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07394114RecruitingPhase 3
Study of a new medicine for type 2 diabetes not controlled by diet and exercise
This trial tests a new medicine called HDM1005 for people with type 2 diabetes who haven't been helped enough by diet and exercise alone, and who haven't taken any diabetes medication in the last 12 weeks. It aims to see if the medicine can help lower blood sugar levels safely.
BeijingAges 18–75 - NCT07395687RecruitingPhase 2
Study of UBT251 for people with overweight or obesity
This trial tests different doses of UBT251, a new medicine, to see how well it helps people lose weight. It may be an option if you have overweight or obesity and meet certain age and BMI requirements.
Cypress, CaliforniaAges 18–65 - NCT07396337RecruitingPhase 2
Study of QHRD106 injection for acute ischemic stroke
This trial tests an investigational drug, QHRD106, given as an injection for people who have had a moderate-to-severe acute ischemic stroke. It aims to see if the drug can help recovery when given within 24 hours after the stroke starts, and it is for patients who are not receiving standard clot-busting treatment.
Nanjing, JiangsuAges 18–80 - NCT07397468RecruitingPhase 1/Phase 2
Study of JUV-161 for leg immobilization recovery
This trial tests a drug called JUV-161 to see if it can help protect muscle from loss when a leg is immobilized (in a cast or boot). It is for healthy adults who are willing to undergo a leg immobilization period and muscle biopsy.
AucklandAges 45–65 - NCT01785420RecruitingPhase 3
Trastuzumab before breast surgery for HER2-positive cancer
This trial tests whether giving trastuzumab before surgery can improve outcomes for people with HER2-positive early breast cancer. Trastuzumab is a targeted medicine that helps treat HER2-driven cancer before the tumor is removed.
MumbaiAges 18–80 - NCT00409435RecruitingPhase 2
Pyridostigmine trial for postural tachycardia syndrome symptoms
This trial tests whether pyridostigmine helps people with postural tachycardia syndrome (POTS), which causes heart rate to rise when you stand up and can lead to unpleasant symptoms. You would be screened based on your tilt-table heart-rate response and your standing-related symptoms.
Rochester, MinnesotaAges 15–55 - NCT02064673RecruitingPhase 3
Adjuvant curcumin after prostate surgery to prevent cancer return
This Phase 3 trial studies whether taking curcumin (a supplement made from turmeric) after radical prostatectomy can help keep prostate cancer from coming back. Participants are men with low-risk, surgery-only disease and undetectable PSA, and the study checks recurrence-free survival over time.
Dallas, TexasAges 30–80 - NCT01945840Recruiting
Study how gut hormones change after weight-loss surgery
This study looks at how gut hormones and blood sugar control change after Roux-en-Y gastric bypass. It may help researchers understand what supports healthier glucose levels after bariatric surgery.
London, Greater LondonAges 18–70 - NCT01712620RecruitingPhase 2
Spironolactone for pulmonary arterial hypertension in stable patients
This trial studies whether spironolactone can improve pulmonary arterial hypertension, a disease that makes the blood vessels in the lungs work too hard. You may be eligible if your condition is confirmed by specific heart-lung pressure tests and your medication plan has been stable for at least 4 weeks.
Bethesda, MarylandAges 18–100 - NCT00929006RecruitingEarly Phase 1
Testing progesterone effects on hormone timing during sleep in teens
This early-phase study tests whether a progesterone medicine can change when “luteinizing hormone” (a puberty-related hormone) pulses during wake versus sleep. It focuses on pubertal girls with either normal or higher-than-expected testosterone levels to see how their hormone timing responds.
Charlottesville, VirginiaAges 10–17 - NCT02897700RecruitingPhase 1
Testing chemotherapy choices for early breast cancer after surgery
This Phase 1 study tests different chemotherapy approaches in people with breast cancer that has been surgically removed but is early stage. It aims to find a chemotherapy plan that’s safe and works well right after surgery.
Ganzhou, JiangxiAges 18 years+ - NCT02502162Recruiting
Low-dose naltrexone for complex regional pain syndrome
This trial tests whether low-dose naltrexone can reduce symptoms of complex regional pain syndrome (CRPS), a long-lasting pain condition in an arm or leg. It may help by targeting pain signaling, but you must meet specific CRPS diagnosis and medication rules to join.
Palo Alto, CaliforniaAges 18–70 - NCT02455479RecruitingPhase 1
Safety study of a vaccine for cocaine dependence
This early-stage study tests how safe an experimental “cocaine vaccine” is and how the body reacts to it. You must also be in behavioral therapy, and the study aims to see whether the vaccine can be given safely to people with cocaine use disorder.
New York, New YorkAges 21–69 - NCT02889666RecruitingPhase 1
Chemo plus surgery for recurrent lung cancer
This Phase 1 trial tests whether giving chemotherapy along with surgery is safe and tolerable for people with recurrent non-small cell lung cancer. It may help guide future treatment for cancer that has returned, especially if it has not spread to distant sites.
Changchun, JilinAges 18–75 - NCT02781519RecruitingPhase 1
Study how THC affects men and women who have used cannabis before
This Phase 1 study tests how delta-9 THC (the main active ingredient in cannabis) affects healthy adults, and whether the effects differ by gender. It may help researchers understand risks and responses to THC, which could guide safer use and future treatments.
West Haven, ConnecticutAges 18–55 - NCT02423395RecruitingPhase 3
Orphenadrine for muscle cramps in people with cirrhosis
This trial tests whether orphenadrine (a medication used to reduce muscle cramping) can lessen muscle cramps in people who have cirrhosis of the liver. It may help if your cramps happen often, but you must avoid certain medication conflicts and health situations.
TantaAges Any age - NCT02484248RecruitingPhase 3
Ketotifen for kids with stomach pain and duodenal eosinophilia
This study tests whether ketotifen can improve long-lasting stomach pain in children whose biopsies show high levels of a certain immune cell type in the small intestine. It may help if standard stomach-acid medicines and montelukast did not work well enough.
Kansas City, MissouriAges 8–17 - NCT02811510RecruitingPhase 1
Study of THC effects on people with past cannabis use
This Phase 1 study tests how THC (the main active ingredient in cannabis) affects healthy adults, and whether effects differ by gender. It’s designed to learn about short-term body and brain responses to THC.
West Haven, ConnecticutAges 18–55 - NCT02608996RecruitingPhase 1/Phase 2
Nesiritide test for hard-to-control blood pressure
This Phase 1/2 study tests nesiritide, a medicine that affects blood vessels and heart strain, to see if it can improve blood pressure control in people with hypertension. It’s mainly for people whose blood pressure stays high even during the day despite medication.
OsloAges 18–79 - NCT02314988RecruitingPhase 2/Phase 3
Tranexamic acid to reduce bleeding in spine surgery
This trial tests whether tranexamic acid (a medicine that helps blood clot) can reduce blood loss during long spine surgery after an injury. It may help lower the chance of needing transfusions and manage surgical bleeding.
San Francisco, CaliforniaAges 18–80 - NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT02411773RecruitingPhase 1
Test a nerve-blocking medicine in kidney disease
This Phase 1 study tests whether a medicine that reduces nerve signals (“sympatholysis”) is safe and how it affects people with chronic kidney disease. It may help researchers understand new ways to protect the kidneys, but the main goal here is safety.
Decatur, GeorgiaAges 18–75 - NCT02902198Recruiting
Study of taste changes before and after bariatric surgery
This study looks at how your sense of taste works before and after bariatric weight-loss surgery. It may help doctors understand why eating patterns change after surgery.
BaselAges 18–55
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,219 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.