Clinical trials
Scoliosis clinical trials
Below are recruiting scoliosis clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07331298Recruiting
Water movement in spine discs of children
This study uses routine MRI scans to measure water movement in the spine discs of children aged 8–16. It aims to understand normal disc health and how it changes in children with scoliosis (a curve in the spine).
LimogesAges 8–16 - NCT07332780Recruiting
Tonsil and adenoid surgery for kids with mild breathing troubles during sleep
This study looks at whether removing tonsils and adenoids can help improve spine curves in children who have mild sleep-disordered breathing. It may help prevent scoliosis from getting worse.
Wenzhou, ZhejiangAges 6–15 - NCT07261358Recruiting
3D exercises for teens with rounded upper back
This trial tests whether specific three-dimensional exercises (Schroth method) can improve trunk muscle endurance, sleep quality, and quality of life in adolescents with hyperkyphosis (excessive forward curve of the upper spine). If you have a child between 12 and 18 with a Cobb angle of 45° or more in the upper back, this study may help.
IstanbulAges 12–18 - NCT06992622Recruiting
Youth spine and vision health study
This study is following a group of young people with scoliosis to better understand how their spine and vision change over time. It may help you learn more about your condition and contribute to future care.
Wenzhou, ZhejiangAges 6–17 - NCT06935331Enrolling by invitationPhase 4
Opioid-free spinal fusion for teens with scoliosis
This trial tests a way to manage pain after scoliosis surgery without using opioid medications. It aims to see if patients can recover comfortably using only non-opioid pain relievers, which may help avoid opioid side effects and addiction risks.
Charlotte, North CarolinaAges 10–20 - NCT06910228Enrolling by invitation
Brain oxygen changes during spine surgery position shifts
This study measures how your child's brain oxygen levels change when they are repositioned during spine surgery. It may help make surgeries safer for teens and young adults.
Columbus, OhioAges 10–21 - NCT06087510RecruitingPhase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery
This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06626503RecruitingPhase 3
Pain medicine study for children having spine surgery
This study tests a pain medicine (methadone) for children and teens having spine fusion surgery for scoliosis. It aims to see if it helps control pain safely.
Indianapolis, IndianaAges 10–18 - NCT06498232Enrolling by invitation
Video game exercises after scoliosis surgery
This trial compares active video game-based exercises with standard stability training in teens who had surgery for severe scoliosis. It aims to see if fun, interactive games can improve recovery just as well as traditional stability training.
IstanbulAges 10–18 - NCT06357234RecruitingPhase 2
Aprepitant to prevent nausea after child scoliosis surgery
This trial tests if a drug called Aprepitant, given before surgery, can better prevent nausea and vomiting after scoliosis repair in children. It is for children aged 8 to 18 who are having spinal fusion surgery for a certain type of scoliosis.
Halifax, Nova ScotiaAges 8–19 - NCT06315933Recruiting
Anesthesia and brain development in children with congenital scoliosis
This study looks at how anesthesia (medicine used to put children to sleep during surgery) may affect the brain development of children with congenital scoliosis. It will help doctors understand how to make anesthesia safer for children with this condition.
Beijing, Beijing MunicipalityAges 6–16 - NCT06226272Recruiting
Study of Stryker spine device results
This trial is checking how well a Stryker spine device works in people who need spine surgery. Eligibility depends on the specific device and is decided by the study doctors.
Jacksonville, FloridaAges 18 years+ - NCT06067893Enrolling by invitationPhase 2
Low dose sedation medicine for pain after scoliosis surgery
This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.
Kansas City, MissouriAges 10–21 - NCT05866419Recruiting
Study of a port and catheter system for spinal muscular atrophy
This study tests a new device called the ThecaFlex DRx System, which is a small port and catheter placed under the skin to deliver Spinraza directly into spinal fluid—instead of needing repeated spinal taps. The device aims to make receiving medication easier and safer for people with SMA.
Phoenix, ArizonaAges 3 years+ - NCT05830825Recruiting
Follow-up study for The Tether to treat scoliosis
This study tracks how well The Tether™ (a growth-friendly spine treatment) works and how people do after surgery in the UK. It is for teens with progressive scoliosis who couldn’t stick with bracing and where their doctor has already decided The Tether is appropriate.
LondonAges birth–30 years - NCT05146193Recruiting
AI tool that analyzes spine curves from images
This trial is testing an AI computer system that automatically measures scoliosis and related spine curve problems using medical images. If you qualify, you may be asked to have or allow specific imaging so the system can be checked for accuracy and usefulness.
Hong KongAges 10–80 - NCT05051254Recruiting
Breathing muscle testing in children with breathing muscle weakness
This study looks at how hard it is for children to breathe and how their breathing muscles work, using specific breathing-related tests. It may help doctors better understand breathing problems and choose care more effectively.
ParisAges birth–17 years - NCT04885244Recruiting
Minimally invasive surgery for adult spine bending and misalignment
This trial looks at how well minimally invasive back surgery works for adults with long-lasting spine deformities (like bending or uneven alignment). It aims to measure outcomes using questionnaires and spine X-ray measurements after treatment.
Phoenix, ArizonaAges 18 years+ - NCT04914507Recruiting
Tracking long-term results of spine tethering in growing teens
This study follows kids who have a surgery called anterior vertebral body tethering (AVBT) for growing-related, idiopathic scoliosis. It looks at how well the curve stays corrected over time and how the spine grows, which may help improve future care decisions.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT04888104Recruiting
Testing a spine implant to prevent failure near the top
This study looks at whether using a specific attachment system (VersaTie) with pedicle screws can help prevent problems near the top of a long spinal fusion. It compares outcomes in adults who are planning long posterior spine fusion surgery using this approach.
Phoenix, ArizonaAges 18 years+ - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT04194138Recruiting
Surgery planning study for complex adult spine curvatures
This trial focuses on adults with complex spinal deformities and tests how different surgical approaches fit their x-ray measurements and surgical plans. It may help doctors choose safer, better-tailored surgery for severe adult spine bending or imbalance.
La Jolla, CaliforniaAges 18 years+ - NCT03059420Recruiting
Genetic study of strabismus and certain birth eye-movement disorders
This study looks for genetic (inherited DNA) causes of strabismus (eyes that don’t line up) and certain birth conditions that affect eye movement and brainstem/cranial nerves. Your participation may help researchers better understand these conditions and guide future testing and care.
Boston, MassachusettsAges 1 day+ - NCT00411060Recruiting
Orthopaedic data bank study for acute and chronic problems
This study collects information about orthopedic (bone, joint, muscle) problems from people seen in the orthopaedics clinic. It may help improve future care by organizing real-world clinical data.
Gainesville, FloridaAges Any age
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Common questions
- Are there clinical trials for scoliosis?
- Yes. Clin2 currently lists 120 recruiting scoliosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a scoliosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a scoliosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.