Clinical trials
Severe Brain Injury clinical trials
Below are recruiting severe brain injury clinical trials, each written for real people, not researchers. We’re tracking 277 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07860840Recruiting
Visual training before robot-assisted walking for stroke survivors
This study tests whether a special visual training program before using a walking robot can improve walking recovery in people who have had a stroke or similar brain injury within the last 6 months and have trouble sensing their affected side. If you join, you might get this extra visual practice to help your brain relearn movement.
Negrar, ItalyAges 18–80 - NCT03502967Enrolling by invitationEarly Phase 1
Hyperpolarized carbon-13 brain scan for recent traumatic brain injury
This early study tests a special brain imaging scan that looks at brain metabolism after a recent concussion/traumatic brain injury (TBI). It may help researchers understand what’s happening in the brain soon after injury.
Dallas, TexasAges 18–60 - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT07834476Enrolling by invitation
Setting treatment targets for severe head injury in children
This study looks at information from children who had a serious head injury. It uses data from special brain monitors to help doctors decide how to best manage these injuries.
Cambridge, CambridgeshireAges 1 month–18 years - NCT07109804Recruiting
Deep brain stimulation to improve walking after spinal cord injury
This study tests whether stimulating a small area deep in the brain (the cuneiform nucleus) with a device called deep brain stimulation (DBS) can help people walk better after a spinal cord injury. The goal is to see if it improves walking speed and stability.
Miami, FloridaAges 22–70 - NCT07858708Enrolling by invitation
Vision problems after brain injury
This study looks at vision problems that can happen after a brain injury, like a stroke, traumatic brain injury, or brain tumor. The researchers want to understand how these vision issues affect daily life, which could help improve care.
Prague, Česká RepublikaAges 18–85 - NCT07463027Enrolling by invitation
Veteran brain injury rehab with integrated care
This trial tests a 3-week rehabilitation program for veterans with traumatic brain injury and other conditions. It aims to improve recovery through team-based care.
Milwaukee, WisconsinAges 18–65 - NCT07135791Recruiting
Tracking daily fatigue in adults with brain injury or cerebral palsy
This study uses a smartphone app to track how fatigue changes throughout the day in adults with cerebral palsy or acquired brain injury. The goal is to better understand fatigue patterns so doctors can offer better support.
Glostrup MunicipalityAges 30–65 - NCT04869059Recruiting
tDCS for mild brain injury memory word finding
This trial tests whether a noninvasive brain stimulation treatment (tDCS) can improve word-retrieval problems after a mild or moderate concussion-like brain injury. It may help if testing shows trouble finding the right words when speaking.
Dallas, TexasAges 18–75 - NCT07073378Recruiting
Brain-computer help for youth with severe disabilities
This study tests if a brain-computer interface (a device that reads brain signals) can help children and teens with severe physical or communication challenges do things at home, like moving a cursor or expressing themselves.
Calgary, AlbertaAges 5–18 - NCT05741411Recruiting
Text-and-phone support after concussion for teens
This study tests whether a phone-based (mHealth) handoff and follow-up can help teens after a concussion, especially those at higher risk of long-lasting symptoms. It uses smartphone check-ins and coordination between emergency and specialty care.
Philadelphia, PennsylvaniaAges 13–18 - NCT07269457RecruitingPhase 2
Vitamin D3 for recovery after mild to moderate brain injury
This trial tests if taking vitamin D3 can help reduce swelling and speed up recovery after a mild to moderate traumatic brain injury. It is for people who have low vitamin D levels.
LagosAges 18–65 - NCT06529380Recruiting
Brain stimulation for severe self-harm in children with autism
This study tests whether deep brain stimulation can reduce severe self-injurious behaviors in children with autism. If standard treatments haven't worked, this approach may offer a new option.
Toronto, OntarioAges 5–17 - NCT07490418Recruiting
Brain injury screening for mild head trauma or neurological symptoms
This trial tests a device (TES HT100) to screen for brain injuries in people with mild head trauma or certain neurological symptoms. It aims to quickly identify who might need imaging or follow-up care.
Castel Volturno, CEAges 18 years+ - NCT07548580Recruiting
Early Movement Therapy for Brain Injury in Hospital ICU
This study looks at how gentle, early physical movement during ICU care affects recovery in patients with serious brain injuries like stroke or head trauma. Researchers will track how patients respond to a structured movement program while they're on a breathing machine.
CopenhagenAges 18 years+ - NCT04602806Enrolling by invitation
Precision medicine study for traumatic brain injury
This study is looking at people with traumatic brain injuries to improve how they are treated. If you join, you will get an MRI and other tests within the first two days after your injury, and the researchers will track your recovery over time.
San Francisco, CaliforniaAges 18–65 - NCT04867317RecruitingPhase 3
Growth hormone treatment for veterans with mild traumatic brain injury and hormone deficiency
This study tests whether giving growth hormone, a natural substance that helps the body grow and repair tissues, can improve symptoms in veterans who have both a mild traumatic brain injury (concussion) and a deficiency in growth hormone. If you qualify, you may receive the treatment or a placebo (inactive shot), and the study will track your quality of life and symptoms over time.
Birmingham, AlabamaAges 21–55 - NCT06188364RecruitingEarly Phase 1
Helping caregivers of traumatic brain injury patients
This trial tests if mobile health support (texts and calls) helps caregivers of people with traumatic brain injury after rehab. You may join as the main caregiver if you supervise daily care and have a smartphone or can get one.
Richmond, VirginiaAges 18 years+ - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT07230002Recruiting
Navigating in virtual worlds after brain injury
This study looks at how people who had a moderate or severe traumatic brain injury at least 3 months ago walk and navigate in complex virtual environments. Participants will use virtual reality to test their movement strategies.
RennesAges 18–55 - NCT07635329Recruiting
Home Vision Therapy Guided by Brain Scans
This study tests whether vision rehabilitation exercises done at home, guided by brain imaging, can help people regain vision after a stroke, brain injury, or tumor. Participants will use brain scans to personalize their therapy.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07749625Recruiting
Robotic arm training for recovery after stroke or injury
This study tests whether a robotic arm trainer can help improve arm movement and function in people with conditions like stroke, spinal cord injury, or brain injury. It may help you regain strength and control in your arm.
DhakaAges 18–60 - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT06065046RecruitingPhase 2
Baricitinib for traumatic brain bleeding
This trial tests if baricitinib, an anti-inflammatory drug, can help people with bleeding in the brain from a head injury. It is for adults with moderate to severe traumatic brain injury who are not immediately having surgery.
Xi'an, ShaanxiAges 18–80
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Common questions
- Are there clinical trials for severe brain injury?
- Yes. Clin2 currently lists 277 recruiting severe brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.