Clinical trials
Shock clinical trials
Below are recruiting shock clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07388628Recruiting
Observing ARTICE® treatment in the ICU
This study is collecting real-world data on ARTICE® treatment for adults in the ICU. It helps doctors understand how this treatment works in daily practice.
MagdeburgAges 18 years+ - NCT03401398RecruitingPhase 3
Hydrocortisone for children with septic shock in the ICU
This Phase 3 trial tests whether giving stress-dose hydrocortisone can improve outcomes for children with septic shock in the pediatric intensive care unit (PICU). It is designed for children who are already receiving strong medicines to support blood pressure because of a serious infection.
Tucson, ArizonaAges 1 month–17 years - NCT03547414Recruiting
Urine markers to predict kidney injury worsening in septic shock
This study tests whether two substances in urine (TIMP2 and IGFBP7) can help doctors predict which patients with sepsis-related kidney problems will get worse. If these markers work, doctors could identify high-risk patients earlier and treat them more aggressively.
AmiensAges 18 years+ - NCT03559569Recruiting
Study blood changes in people with circulatory shock
This study looks at how blood vessel and white blood cell aging changes during circulatory shock. Your participation may help doctors better understand what’s happening in the body during shock.
StrasbourgAges 18 years+ - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT04020263RecruitingPhase 3
Levosimendan early treatment vs placebo for cardiogenic shock
This study tests whether giving levosimendan early (a heart-strengthening medicine) improves outcomes compared with placebo, on top of standard inotropic support, in people with cardiogenic shock. It mainly looks at whether patients have fewer serious complications or deaths.
Strasbourg, Bas-RhinAges 18 years+ - NCT04184635Recruiting
ECMO for heart-attack shock in the ICU
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
ParisAges 18 years+ - NCT04419480Recruiting
Monitoring to help prevent complications after cardiogenic shock
This study tests a special monitoring approach (likely using an implanted device) to help prevent serious complications after you survive cardiogenic shock in the hospital. It may help the care team detect problems earlier so treatments can start sooner.
Falls Church, VirginiaAges 18 years+ - NCT04494074Recruiting
Cooling fever in ventilated people with septic shock
This study tests whether external cooling can safely lower very high fever in people who are on a breathing machine for septic shock. It may help improve outcomes by controlling fever while they are treated for the infection causing their illness.
AmiensAges 18 years+ - NCT04513288Recruiting
Immunonutrition with L-citrulline for ICU sepsis patients
This trial tests whether adding L-citrulline to tube feeding (enteral nutrition) can improve outcomes for people in the ICU with sepsis or septic shock. It may help support the body’s immune response while you’re critically ill.
Rennes, Brittany RegionAges 18 years+ - NCT04682483Recruiting
Cardiogenic shock registry to improve care and outcomes
This registry collects information about people who have cardiogenic shock, a serious condition where the heart cannot pump enough blood. Your participation may help doctors learn which treatments and monitoring best improve outcomes.
Weston, FloridaAges 18 years+ - NCT04844801Recruiting
Prevent fast heart rhythms during sepsis shock with rate control drugs
This trial tests whether a heart-rate–controlling medication can better manage a new fast heart rhythm that happens during sepsis shock. It may help reduce heart strain and improve safety compared with standard care.
ParisAges 18 years+ - NCT04855786Recruiting
Drain lymph fluid to reduce inflammation in septic shock
This study tests whether draining fluid from a chest lymph channel can lower inflammation chemicals (cytokines) in people with septic shock. It’s done using a procedure and aims to see if this helps stabilize the body’s inflammatory response.
Philadelphia, PennsylvaniaAges 18–80 - NCT04067674Recruiting
Study immune changes in adults with septic shock
This trial looks at how the immune system changes after septic shock in adults in the ICU. It may help doctors better predict or manage complications by studying blood markers a few days after starting treatment.
LyonAges 18 years+ - NCT05057611Recruiting
Tested blood-pressure rescue strategy using skin refill time
This study looks at a specific resuscitation (rescue) approach for adults in septic shock, using a bedside skin test called capillary refill time. If you qualify, the goal is to see whether this approach better stabilizes your body and improves outcomes.
Santiago, Santiago MetropolitanAges 18 years+ - NCT05093075RecruitingPhase 2
Plasma exchange for ICU patients with severe septic shock
This study tests whether therapeutic plasma exchange (a procedure that removes and replaces blood plasma) can improve outcomes in ICU patients with septic shock that is not responding to standard medicines. It may help some people whose infection-related illness is causing failing organs.
Calgary, AlbertaAges 16 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05168462RecruitingPhase 4
Lower blood pressure goal in heart-attack shock patients
This study compares two blood pressure targets in people with cardiogenic shock after a heart attack. It looks at whether the lower target can improve outcomes and help evaluate treatment costs.
AmsterdamAges 18 years+ - NCT05185492Recruiting
Registry for treatment outcomes in cardiogenic shock
This trial is a registry that collects information about people with cardiogenic shock to better understand outcomes and improve management. It may help by contributing real-world data on what treatments and timing work best for different heart-related shock causes.
Weston, FloridaAges 18 years+ - NCT05267886RecruitingPhase 4
Testing an inotrope medicine versus placebo in shock patients
This trial studies whether an inotrope medicine (a drug that helps the heart pump) works better than a placebo in adults in intensive care with cardiogenic shock. It may help doctors find safer, more effective treatment for this life-threatening condition.
Rochester, MinnesotaAges 18 years+ - NCT05298124Recruiting
Repairing a leaking mitral valve in severe heart shock
This trial tests a catheter-based procedure to repair a leaking mitral valve in people who are in severe heart shock and need medication support. The goal is to reduce the valve leak and see if it helps patients stabilize and recover.
Rochester, MinnesotaAges 18 years+ - NCT05349370Recruiting
Track how lactate levels change in septic shock
This study measures how quickly a blood marker called lactate rises or falls in people with septic shock. It may help doctors understand which patterns are linked to recovery and guide better treatment decisions.
Stockholm, Stockholm CountyAges 18 years+ - NCT05366452Recruiting
Early heart pump implant for shock after a heart attack
This trial studies whether putting in a small heart pump early (through the leg) helps people with a heart attack complicated by severe heart weakness (“cardiogenic shock”) compared with standard treatment. It aims to improve survival and recovery by supporting blood flow sooner.
Marseille, Bouche DU RhoneAges 18–80 - NCT05383963Recruiting
Using ICU routine data to diagnose sepsis sooner
This study checks whether information collected routinely in the ICU can help doctors recognize sepsis or septic shock earlier. If it works, it may improve how quickly diagnosis happens and potentially outcomes for patients.
BerlinAges 18 years+
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Common questions
- Are there clinical trials for shock?
- Yes. Clin2 currently lists 328 recruiting shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.